PIPA576801

TET2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA576801-Each-of-1 In Stock ₹ 47,528.58

PIPA576801 - Each of 1

₹ 47,528.58

In Stock

Quantity

1

Base Price: ₹ 47,528.58

GST (18%): ₹ 8,555.144

Total Price: ₹ 56,083.724

Antigen

TET2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TET2

Gene Alias

Ayu17-449; E130014J05Rik; FLJ20032; KIAA1546; MDS; methylcytosine dioxygenase TET2; MGC125715; mKIAA1546; Nbla00191; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Protein Ayu17-449; RGD1311625; Tet 2; tet methylcytosine dioxygenase 2; tet oncogene 2; tet oncogene family member 2; TET2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

214133, 310859, 54790

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.

Q4JK59, Q6N021

Gene Symbols

TET2

Immunogen

Recombinant full length Human TET2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • TET2 is a dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydromethylcytosine (5hmC) and plays a key role in active DNA demethylation
  • TET2 has a preference for 5-hydroxymethylcytosine in CpG motifs
  • It mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC) and conversion of 5fC to 5-carboyxlcytosine (5caC)
  • Conversion of 5mC into 5hmC, 5fC, and 5caC probably constitutes the first step in cytonsine demethylation
  • In addition to TET2’s role in DNA demethylation, it is also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT
  • Mutations in the genes can result in Polycythemia vera and Myelodysplastic syndrome.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA576801

--


Antigen:
TET2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TET2

Gene Alias:
Ayu17-449; E130014J05Rik; FLJ20032; KIAA1546; MDS; methylcytosine dioxygenase TET2; MGC125715; mKIAA1546; Nbla00191; OTTHUMP00000161869; probable methylcytosine dioxygenase TET2; Protein Ayu17 449; Protein Ayu17-449; RGD1311625; Tet 2; tet methylcytosine dioxygenase 2; tet oncogene 2; tet oncogene family member 2; TET2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
214133, 310859, 54790

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
Q4JK59, Q6N021

Gene Symbols:
TET2

Immunogen:
Recombinant full length Human TET2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA576802

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Antigen:
GRB7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRB7

Gene Alias:
B47; Epidermal growth factor receptor GRB-7; Grb7; GRB7 adapter protein; growth factor receptor binding protein GRB7; growth factor receptor bound protein 7; growth factor receptor-bound protein 7; Growth factor receptor-bound protein 7 (GRB7 adapter protein) (Epidermal growth factor receptor GRB-7); mKIAA4028; OTTHUMP00000164352

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14786, 2886

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q03160, Q14451

Gene Symbols:
GRB7

Immunogen:
Recombinant full length Human GRB7.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA576804

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Antigen:
EEF1B2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EEF1B2

Gene Alias:
2810017J07Rik; EEF1B; EEF1B1; EEF1B2; EF1B; EF-1-beta; Elongation factor 1-beta; eukaryotic translation elongation factor 1 beta 1; eukaryotic translation elongation factor 1 beta 2; eukaryotic translation elongation factor 1-beta homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1933, 363241, 55949

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O70251, P24534

Gene Symbols:
EEF1B2

Immunogen:
Recombinant full length Human EEF1B2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA576805

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Antigen:
CRX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Crx

Gene Alias:
Cone rod homeobox; cone-rod homeobox; cone-rod homeobox containing; cone-rod homeobox protein; CORD 2; CORD2; CRD; CRX; Crx1; LCA 7; LCA7; orthodenticle homeobox 3; OTX; OTX 3; OTX3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12951, 1406, 60446

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.2

Gene Accession No.:
O43186, O54751

Gene Symbols:
Crx

Immunogen:
Recombinant full length Human CRX.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG