PIPA576932
PTPRN Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA576932-Each-of-1 | In Stock | ₹ 48,041.94 |
PIPA576932 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,041.94
GST (18%): ₹ 8,647.549
Total Price: ₹ 56,689.489
Antigen
PTPRN
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTPRN
Gene Alias
105 kDa islet cell antigen; BEM-3; brain-enriched membrane-associated protein tyrosine phosphatase; IA2; IA-2; IA-2/PTP; ICA 512; ICA105; ICA3; ICA512; ICA512-CCF; ICA512-cleaved cytosolic fragment; ICA512-N-terminal fragment; ICA512-NTF; ICA512-TMF; ICA512-transmembrane fragment; islet cell antigen 2; islet cell antigen 512; Islet cell autoantigen 3; mIA-A; mKIAA4064; protein tyrosine phosphatase, receptor type N; protein tyrosine phosphatase, receptor type, N; protein tyrosine phosphatase, receptor-type, N; protein tyrosine phosphatase-like N; PTP IA-2; PTPLP; Ptprn; receptor-type tyrosine-protein phosphatase-like N; R-PTP-N
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116660, 19275, 5798
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
Q16849, Q60673, Q63259
Gene Symbols
PTPRN
Immunogen
Recombinant full length Human PTPRN.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
- IA-2 (insulinoma-associated protein 2, ICA512, PTPRN) is a member of the transmembrane protein tyrosine phosphatase (PTP) family located in secretory granules of neuroendocrine cells
- The IA-2 protein is 979 amino acids in length and consists of a luminal domain, transmembrane domain, and cytoplasmic domain
- Although a member of the PTP family, IA-2 lacks phosphatase activity with known substrates due to amino acid substitutions at critical sites in its PTP domain
- Two paralog RPTPs, IA-2 and IA-2beta were identified as major autoantigens in type-1 diabetes mellitus
- On granule exocytosis, the IA-2 cytoplasmic domain is cleaved and the resulting cytosolic fragment moves into the nucleus where it enhances the levels of phosphorylated STAT5 and STAT3, thereby inducing insulin gene transcription and granule biogenesis
- IA-2 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs.
Compare Similar Items
Show Difference
Antigen: PTPRN
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTPRN
Gene Alias: 105 kDa islet cell antigen; BEM-3; brain-enriched membrane-associated protein tyrosine phosphatase; IA2; IA-2; IA-2/PTP; ICA 512; ICA105; ICA3; ICA512; ICA512-CCF; ICA512-cleaved cytosolic fragment; ICA512-N-terminal fragment; ICA512-NTF; ICA512-TMF; ICA512-transmembrane fragment; islet cell antigen 2; islet cell antigen 512; Islet cell autoantigen 3; mIA-A; mKIAA4064; protein tyrosine phosphatase, receptor type N; protein tyrosine phosphatase, receptor type, N; protein tyrosine phosphatase, receptor-type, N; protein tyrosine phosphatase-like N; PTP IA-2; PTPLP; Ptprn; receptor-type tyrosine-protein phosphatase-like N; R-PTP-N
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116660, 19275, 5798
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q16849, Q60673, Q63259
Gene Symbols: PTPRN
Immunogen: Recombinant full length Human PTPRN.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PTPRN
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTPRN
Gene Alias:
105 kDa islet cell antigen; BEM-3; brain-enriched membrane-associated protein tyrosine phosphatase; IA2; IA-2; IA-2/PTP; ICA 512; ICA105; ICA3; ICA512; ICA512-CCF; ICA512-cleaved cytosolic fragment; ICA512-N-terminal fragment; ICA512-NTF; ICA512-TMF; ICA512-transmembrane fragment; islet cell antigen 2; islet cell antigen 512; Islet cell autoantigen 3; mIA-A; mKIAA4064; protein tyrosine phosphatase, receptor type N; protein tyrosine phosphatase, receptor type, N; protein tyrosine phosphatase, receptor-type, N; protein tyrosine phosphatase-like N; PTP IA-2; PTPLP; Ptprn; receptor-type tyrosine-protein phosphatase-like N; R-PTP-N
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116660, 19275, 5798
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q16849, Q60673, Q63259
Gene Symbols:
PTPRN
Immunogen:
Recombinant full length Human PTPRN.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RBP3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RBP3
Gene Alias: D10S64; D10S65; D10S66; interphotoreceptor retinoid binding protein; interphotoreceptor retinoid-binding protein; interphotoreceptor retinol- binding protein; interstitial retinol binding protein 3; interstitial retinol-binding protein; interstitial retinol-binding protein 3; IRBP; RBP3; Rbp-3; RBPI; retinol binding protein 3; retinol binding protein 3, interstitial; retinol-binding protein 3; RP66
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19661, 24711, 5949
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P10745, P49194
Gene Symbols: RBP3
Immunogen: Recombinant full length Human RBP3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RBP3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RBP3
Gene Alias:
D10S64; D10S65; D10S66; interphotoreceptor retinoid binding protein; interphotoreceptor retinoid-binding protein; interphotoreceptor retinol- binding protein; interstitial retinol binding protein 3; interstitial retinol-binding protein; interstitial retinol-binding protein 3; IRBP; RBP3; Rbp-3; RBPI; retinol binding protein 3; retinol binding protein 3, interstitial; retinol-binding protein 3; RP66
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19661, 24711, 5949
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P10745, P49194
Gene Symbols:
RBP3
Immunogen:
Recombinant full length Human RBP3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TRIM27
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TRIM27
Gene Alias: AW538890; Gm19403; ret finger protein; ret finger protein 1; RFP; RFP transforming protein; Rfp1; RING finger protein 76; RING-type E3 ubiquitin transferase TRIM27; RNF76; Trim27; tripartite motif containing 27; tripartite motif protein 27; tripartite motif protein TRIM27; tripartite motif-containing 27; tripartite motif-containing protein 27; Zinc finger protein RFP
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19720, 291171, 5987
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P14373, Q62158
Gene Symbols: TRIM27
Immunogen: Recombinant full length Human TRIM27.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TRIM27
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TRIM27
Gene Alias:
AW538890; Gm19403; ret finger protein; ret finger protein 1; RFP; RFP transforming protein; Rfp1; RING finger protein 76; RING-type E3 ubiquitin transferase TRIM27; RNF76; Trim27; tripartite motif containing 27; tripartite motif protein 27; tripartite motif protein TRIM27; tripartite motif-containing 27; tripartite motif-containing protein 27; Zinc finger protein RFP
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19720, 291171, 5987
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P14373, Q62158
Gene Symbols:
TRIM27
Immunogen:
Recombinant full length Human TRIM27.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SFRP4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SFRP4
Gene Alias: Ddc4; DDC-4 protein; Frizzled protein, human endometrium; frizzled related protein; frizzled-related protein; frizzled-related protein 4; FRP; FRP-4; FRPHE; MGC26498; secreted frizzled related protein 4; secreted frizzled-related protein 4; secreted frizzled-related protein 4; secreted frizzled-related protein 4; secreted frizzled-related sequence protein 4; Sfrp4; sFRP-4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20379, 6424, 89803
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q6FHJ7, Q9JLS4, Q9Z1N6
Gene Symbols: SFRP4
Immunogen: Recombinant full length Human SFRP4.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SFRP4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SFRP4
Gene Alias:
Ddc4; DDC-4 protein; Frizzled protein, human endometrium; frizzled related protein; frizzled-related protein; frizzled-related protein 4; FRP; FRP-4; FRPHE; MGC26498; secreted frizzled related protein 4; secreted frizzled-related protein 4; secreted frizzled-related protein 4; secreted frizzled-related protein 4; secreted frizzled-related sequence protein 4; Sfrp4; sFRP-4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20379, 6424, 89803
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q6FHJ7, Q9JLS4, Q9Z1N6
Gene Symbols:
SFRP4
Immunogen:
Recombinant full length Human SFRP4.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG