PIPA577044

NPHP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA577044-Each-of-1 In Stock ₹ 47,614.14

PIPA577044 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

NPHP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NPHP1

Gene Alias

JBTS4; juvenile nephronophthisis 1 protein; nephrocystin 1; Nephrocystin1; nephrocystin-1; nephronophthisis 1 (juvenile); nephronophthisis 1 (juvenile) homolog; nephronophthisis 1 (juvenile) homolog (human); NPH1; NPHP1; SLSN1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

296136, 4867, 53885

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O15259, Q9QY53

Gene Symbols

NPHP1

Immunogen

Recombinant full length Human NPHP1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
  • Juvenile nephronophthisis type 1 is caused by mutations of NPHP1, the gene encoding for nephrocystin
  • Nephrocystin interacts with p130Cas (BCAR1), proline-rich tyrosine kinase-2 (PTK2B or Pyk2), and tensin in embryonic kidney and testis, indicating that these proteins participate in a common signaling pathway
  • Nephrocystin and p130Cas interact in mammalian cells and both proteins prominently localize at or near sites of cell-cell contact in polarized Madin-Darby canine kidney epithelial cells
  • Expression of nephrocystin results in phosphorylation of Pyk2 on Tyrosine 402 as well as activation of downstream mitogen-activated protein kinases, such as ERK1 and ERK2
  • Nephrocystin contains a src-homology 3 (SH3) domain, which is highly conserved throughout evolution.

Compare Similar Items

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Thermo Scientific

PIPA577044

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Antigen:
NPHP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPHP1

Gene Alias:
JBTS4; juvenile nephronophthisis 1 protein; nephrocystin 1; Nephrocystin1; nephrocystin-1; nephronophthisis 1 (juvenile); nephronophthisis 1 (juvenile) homolog; nephronophthisis 1 (juvenile) homolog (human); NPH1; NPHP1; SLSN1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
296136, 4867, 53885

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O15259, Q9QY53

Gene Symbols:
NPHP1

Immunogen:
Recombinant full length Human NPHP1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA577045

--


Antigen:
PLSCR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLSCR1

Gene Alias:
ca(2+)-dependent phospholipid scramblase 1; Erythrocyte phospholipid scramblase; MmTRA1a; MmTRA1b; NOR1; Phospholipid scramblase 1; phospholipid scramblase 2; PL scramblase 1; Plscr1; Tra1; Tra1a; Tra1b; transplantability-associated protein 1; Tras1; Tras2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5359

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O15162

Gene Symbols:
PLSCR1

Immunogen:
Recombinant full length Human PLSCR1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA577047

--


Antigen:
ASM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Smpd1

Gene Alias:
Acid sphingomyelinase; ASM; aSMase; A-SMase; NPD; Smpd1; Sphingomyelin phosphodiesterase; sphingomyelin phosphodiesterase 1; sphingomyelin phosphodiesterase 1, acid lysosomal; Zn-SMase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20597, 308909, 6609

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P17405, Q04519

Gene Symbols:
Smpd1

Immunogen:
Recombinant full length Human ASM.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA577049

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Antigen:
ALOX15

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Alox15

Gene Alias:
12/15-lipoxygenase; 12/15-LO; 12/15-LOX; 12-LO; 12-LOX; 15-lipooxygenase-1; 15-LOX; 15-LOX-1; 15LOX-1; 15-LOX2; Alox12; Alox12l; Alox15; Arachidonate 12-lipoxygenase, leukocyte-type; arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase; L-12LO; LOG15

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11687, 246, 81639

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P16050, P39654, Q02759

Gene Symbols:
Alox15

Immunogen:
Recombinant full length Human ALOX15.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG