PIPA578058

MEKK3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA578058-Each-of-1 In Stock ₹ 47,357.46

PIPA578058 - Each of 1

₹ 47,357.46

In Stock

Quantity

1

Base Price: ₹ 47,357.46

GST (18%): ₹ 8,524.343

Total Price: ₹ 55,881.803

Antigen

MEKK3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Map3k3

Gene Alias

AW548911; MAP/ERK kinase kinase 3; MAP3K3; MAPK/ERK kinase kinase 3; MAPKKK3; MEK kinase 3; MEKK 3; Mekk3; mitogen activated protein kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase 3; mKIAA4031

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26406, 4215

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.71 mg/mL

Formulation

0.1M tris glycine with 0.1M glycine, 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

Q61084, Q99759

Gene Symbols

Map3k3

Immunogen

Recombinant protein encompassing a sequence within the center region of human MEKK3. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Control: 3xFlag-human MAP3K3-transfected 293T Predicted Reactivity: Rat (98%), Rhesus Monkey (100%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • MAP3K3 (MEKK3) directly regulates MAPK8 and extracellular signal-regulated protein kinase (ERK) pathways by phosphorylating multiple MAP2Ks
  • Northern blot analysis revealed a 4
  • 6-kb transcript that appears to be ubiquitously expressed
  • This protein directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively; it does not regulate the p38 pathway
  • In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway
  • Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA578058

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Antigen:
MEKK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Map3k3

Gene Alias:
AW548911; MAP/ERK kinase kinase 3; MAP3K3; MAPK/ERK kinase kinase 3; MAPKKK3; MEK kinase 3; MEKK 3; Mekk3; mitogen activated protein kinase kinase kinase 3; mitogen-activated protein kinase kinase kinase 3; mKIAA4031

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26406, 4215

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.71 mg/mL

Formulation:
0.1M tris glycine with 0.1M glycine, 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q61084, Q99759

Gene Symbols:
Map3k3

Immunogen:
Recombinant protein encompassing a sequence within the center region of human MEKK3. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578059

--


Antigen:
MGMT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MGMT

Gene Alias:
0-6-methylguanine-DNA methyltransferase; 6-O-methylguanine-DNA methyltransferase; Agat; AGT; AI267024; methylated DNA protein cysteine methyltransferase; methylated-DNA--protein-cysteine methyltransferase; methylguanine-DNA methyltransferase; MGMT; O(6)-alkylguanine-DNA alkyltransferase; O-6-alkylguanine-DNA alkyltransferase; O6-alkylguanine-DNA alkyltransferase; O-6-methylguan; O6-methylguanine-DNA methyltranferase; O-6-methylguanine-DNA methyltransferase; O6-methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4255

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 0.1M glycine, 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P16455

Gene Symbols:
MGMT

Immunogen:
Recombinant protein encompassing a sequence within the center region of human MGMT. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578060

--


Antigen:
MGST1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MGST1

Gene Alias:
1500002K10Rik; glutathione S-transferase; glutathione S-transferase 12; Gst; GST12; MGC14525; MGST; mGST1; MGST-I; Microsomal glutathione S-transferase 1; microsomal glutathione S-transferase 1-like protein; microsomal glutathione-S-transferase; microsomal GST-1; Microsomal GST-I

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171341, 4257, 56615

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.41 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P08011, P10620, Q91VS7

Gene Symbols:
MGST1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human MGST1. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578062

--


Antigen:
MLH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mlh1

Gene Alias:
1110035C23Rik; AI317206; AI325952; AI561766; COCA2; colon cancer, nonpolyposis type 2; DNA mismatch repair protein Mlh1; DNA mismatch repair protein Mlh1-like protein; FCC2; hMLH1; HNPCC; HNPCC2; I79_014127; MGC5172; mismatch repair protein 1; MLH1; MLH-1; mutL homolog 1; mutL homolog 1 (E. coli); mutL homolog 1, colon cancer, nonpolyposis type 2; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); mutL protein homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4292

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.83 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P40692

Gene Symbols:
Mlh1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human MLH1. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG