PIPA578249

Phospho-ULK1 (Ser555) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA578249-Each-of-1 In Stock ₹ 47,015.22

PIPA578249 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

Phospho-ULK1 (Ser555)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ULK1

Gene Alias

APG1; ATG 1; ATG1; ATG1 autophagy related 1 homolog; ATG1A; AU041434; Autophagy-related protein 1 homolog; C. elegans; EC:2.7.11.1; FLJ38455; hATG1; KIAA0722; mKIAA0722; Serine/threonine-protein kinase ULK1; serine/threonine-protein kinase Unc51.1; ULK 1; Ulk1; UNC 51; UNC51; unc-51 like autophagy activating kinase 1; unc-51 like kinase 1; Unc51.1; unc-51-like kinase 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8408

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.13 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

O75385

Gene Symbols

ULK1

Immunogen

Recombinant protein encompassing a sequence within the center region of human ULK1 (phospho Ser555). The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Control: MCF-7, MCF-7 (100 μM CCCP treatment for 2 hr) Predicted Reactivity: Mouse (100%), Rat (100%) Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • ULK1 is a serine/threonine protein kinase that plays critical role during initial stages of autophagy which is a vital response to nutrient starvation
  • The conserved C-terminal domain (CTD) of ULK1 controls the regulatory function and localization of the protein
  • Knockdown of ULK1 inhibits the autophagic response as well as inhibiting rapamycin-induced autophagy consistent with a role downstream of mTOR
  • ULK1 forms a complex with FIP200 and ATG13 and this complex is essential for starvation-induced autophagy
  • Both FIP200 and ATG13 are critical for correct localization of ULK1 to the pre-autophagosome and stability of ULK1 protein
  • ULK1 is phosphorylated by the mTOR pathway in a nutrient starvation-regulated manner.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA578249

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Antigen:
Phospho-ULK1 (Ser555)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ULK1

Gene Alias:
APG1; ATG 1; ATG1; ATG1 autophagy related 1 homolog; ATG1A; AU041434; Autophagy-related protein 1 homolog; C. elegans; EC:2.7.11.1; FLJ38455; hATG1; KIAA0722; mKIAA0722; Serine/threonine-protein kinase ULK1; serine/threonine-protein kinase Unc51.1; ULK 1; Ulk1; UNC 51; UNC51; unc-51 like autophagy activating kinase 1; unc-51 like kinase 1; Unc51.1; unc-51-like kinase 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8408

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
O75385

Gene Symbols:
ULK1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human ULK1 (phospho Ser555). The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578252

--


Antigen:
Cullin 4B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CUL4B

Gene Alias:
2700050M05Rik; AA409770; CUL4B; CUL-4B; cullin 4B; cullin-4B; EGK_20888; KIAA0695; mKIAA0695; MRXHF2; MRXS15; MRXSC; RGD1564494; SFM2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
302502, 72584, 8450

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
A2A432, Q13620

Gene Symbols:
CUL4B

Immunogen:
Recombinant protein encompassing a sequence within the center region of human Cullin 4b. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578253

--


Antigen:
SMARCA5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMARCA5

Gene Alias:
4933427E24Rik; D030040M08Rik; D330027N15Rik; hISWI; hSNF2H; ISWI; MommeD4; mSnf2h; SMARCA5; SNF2H; sucrose nonfermenting protein 2 homolog; sucrose nonfermenting-like 5; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5; WCRF135

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
307766, 8467

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.28 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
O60264

Gene Symbols:
SMARCA5

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human SNF2H. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA578254

--


Antigen:
LMO4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LMO4

Gene Alias:
A730077C12Rik; Breast tumor autoantigen; Crp3; ethanol induced 4; Etohi4; LIM domain only 4; LIM domain only protein 4; LIM domain transcription factor LMO4; LIM-only 4 protein; LMO4; LMO-4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8543

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P61968

Gene Symbols:
LMO4

Immunogen:
Full length human LMO4 Recombinant protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG