PIPA579367

HLA-C Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA579367-Each-of-1 In Stock ₹ 39,956.52

PIPA579367 - Each of 1

₹ 39,956.52

In Stock

Quantity

1

Base Price: ₹ 39,956.52

GST (18%): ₹ 7,192.174

Total Price: ₹ 47,148.694

Antigen

HLA-C

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HLA-C

Gene Alias

alpha chain of MHC class II; D6S204; HLA C; HLA class I histocompatibility antigen C alpha chain; HLA class I histocompatibility antigen Cw-1 alpha chain; HLA class I histocompatibility antigen, C alpha chain; HLA class I histocompatibility antigen, Cw-1 alpha chain; HLA class I histocompatibility antigen, Cw-15 alpha chain; HLA class I histocompatibility antigen, Cw-18 alpha chain; HLAC; HLA-C; HLA-C alpha chain; HLA-C alpha chain (HLA-Cw*15v); HLA-C alpha chain for Cw*18GB; HLA-C alpha-chain; HLA-C antigen; HLA-Cw; HLA-Cw*04GB; HLA-Cw*1702; HLA-Cw*18GB; HLA-Cw-1503; HLA-JY3; HLC-C; Human leukocyte antigen C; human leukocyte antigen-C alpha chain; leukocyte antigen C; major histocompatibility antigen HLA-C; major histocompatibility complex, class I, C; MHC; MHC clas I antigen; MHC class 1 antigen; MHC Class I antigen; MHC class I antigen Cw*15; MHC class I antigen Cw*18; MHC class I antigen heavy chain HLA-C; MHC class I histocompatibility antigen; MHC class I molecule; MHC class II antigen; PSORS1; surface antigen; truncated MHC class I antigen

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3107

Content And Storage

-20°C

Form

Lyophilized

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.

P10321

Gene Symbols

HLA-C

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human HLA-C (82-106aa EYWDRETQKYKRQAQADRVNLRKLR).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • HLA-C belongs to the HLA class I heavy chain paralogues
  • This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin)
  • The heavy chain is anchored in the membrane
  • Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen
  • They are expressed in nearly all cells
  • The heavy chain is approximately 45 kDa and its gene contains 8 exons
  • Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail
  • Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule
  • Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
  • Over one hundred HLA-C alleles have been described
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA579367

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Antigen:
HLA-C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLA-C

Gene Alias:
alpha chain of MHC class II; D6S204; HLA C; HLA class I histocompatibility antigen C alpha chain; HLA class I histocompatibility antigen Cw-1 alpha chain; HLA class I histocompatibility antigen, C alpha chain; HLA class I histocompatibility antigen, Cw-1 alpha chain; HLA class I histocompatibility antigen, Cw-15 alpha chain; HLA class I histocompatibility antigen, Cw-18 alpha chain; HLAC; HLA-C; HLA-C alpha chain; HLA-C alpha chain (HLA-Cw*15v); HLA-C alpha chain for Cw*18GB; HLA-C alpha-chain; HLA-C antigen; HLA-Cw; HLA-Cw*04GB; HLA-Cw*1702; HLA-Cw*18GB; HLA-Cw-1503; HLA-JY3; HLC-C; Human leukocyte antigen C; human leukocyte antigen-C alpha chain; leukocyte antigen C; major histocompatibility antigen HLA-C; major histocompatibility complex, class I, C; MHC; MHC clas I antigen; MHC class 1 antigen; MHC Class I antigen; MHC class I antigen Cw*15; MHC class I antigen Cw*18; MHC class I antigen heavy chain HLA-C; MHC class I histocompatibility antigen; MHC class I molecule; MHC class II antigen; PSORS1; surface antigen; truncated MHC class I antigen

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3107

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P10321

Gene Symbols:
HLA-C

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human HLA-C (82-106aa EYWDRETQKYKRQAQADRVNLRKLR).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA579368

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Antigen:
HLA-DMB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLA-DMB

Gene Alias:
class II histocompatibility antigen, M beta chain; D6S221E; DAAP-27A1.4; DMB; HLA class II histocompatibility antigen, DM beta chain; HLA-DMB; major histocompatibility complex, class II, DM beta; MHC class II antigen DMB; MHC class II antigen HLA-DM beta chain; MHC class II HLA-DMB; really interesting new gene 7 protein; RING7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3109

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
P28068

Gene Symbols:
HLA-DMB

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human HLA DMB (81-100aa NQKDTLMQRLRNGLQNCATH).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA579370

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Antigen:
HLA-DQB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLA-DQB1

Gene Alias:
CELIAC1; DQ beta 1; HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1; lymphocyte antigen; major histocompatibility complex, class II, DQ beta 1; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3119

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunocytochemistry, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P01920

Gene Symbols:
HLA-DQB1

Immunogen:
A synthetic peptide corresponding to a sequence of human HLA-DQB1 (DAEYWNSQKEVLERTRAELDTVCRHNYQLELRTTLQRR).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA579372

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Antigen:
HMBS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hmbs

Gene Alias:
alternative name: porphobilinogen deaminase; HEM3; hemC; HMBS; Hydroxymethylbilane synthase; PBG D; PBGD; PBG-D; PORC; Porphobilinogen deaminase; porphyria, acute; Chester type; pre-uroporphyrinogen synthase; similar to Porphobilinogen deaminase (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) (PBG-D); T25658; Ups; uroporphyrinogen I synthase; uroporphyrinogen I synthetase; URO-S; Uros1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15288, 25709, 3145

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P08397, P19356, P22907

Gene Symbols:
Hmbs

Immunogen:
E. coli-derived human HMBS recombinant protein (Position: N6-H361).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG