PIPA579698
Mesothelin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA579698-Each-of-1 | In Stock | ₹ 40,469.88 |
PIPA579698 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,469.88
GST (18%): ₹ 7,284.578
Total Price: ₹ 47,754.458
Antigen
Mesothelin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MSLN
Gene Alias
CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
56047
Content And Storage
-20°C
Form
Lyophilized
Applications
Immunohistochemistry (Paraffin)
Concentration
500 μg/mL
Formulation
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.
Q61468
Gene Symbols
MSLN
Immunogen
E.coli-derived mouse Mesothelin recombinant protein (Position: K308-L576).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- Originally identified as a differentiation antigen of mesotheliomas, ovarian cystadenocarcinomas, and pancreatic adenocarcinomas, Mesothelin is a glycosylphosphatidylinositol (GPI)-anchored, cell-surface glycoprotein predominantly secreted by cells of the mesothelium
- Although Mesothelin is expressed at restricted levels by normal mesothelial cells of the pleural,pericardial, and peritoneal membranes, aberrant expression has been documented in the aforementioned cancers, as well as in endometriod uterine adenocarcinomas and squamous cell carcinomas of the esophagus, stomach, lung, and cervix
- Proteolytic cleavage of Mesothelin yields a soluble, polypeptide fragment designated megakaryocyte potentiating factor (MPF) based on its ability to stimulate megakaryocyte colony-forming activity of murine interleukin-3 in murine bone marrow cell cultures
- Originally isolated from the HPC-Y5 pancreatic cell line, MPF has been suggested to play a role in the proliferation and differentiation of megakaryoctyes, and the regulation of resultant platelet production
- While the biological functions of both Mesothelin and MPF remain speculative, high-levels of expression in cancerous tissues compared to limited distribution in normal tissues strongly suggests their involvement in tumorigenesis
- Both have been demonstrated to promote tumor cell proliferation, migration,anchorage-independent growth, and tumor progression; demonstrating their involvement in heterotypic cell adhesion and the metastatic spread of cancer.
Compare Similar Items
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Antigen: Mesothelin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MSLN
Gene Alias: CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 56047
Content And Storage: -20°C
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin)
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: Q61468
Gene Symbols: MSLN
Immunogen: E.coli-derived mouse Mesothelin recombinant protein (Position: K308-L576).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Mesothelin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MSLN
Gene Alias:
CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; MPF; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
56047
Content And Storage:
-20°C
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin)
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
Q61468
Gene Symbols:
MSLN
Immunogen:
E.coli-derived mouse Mesothelin recombinant protein (Position: K308-L576).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: MTA1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MTA1
Gene Alias: metastasis associated 1; metastasis associated gene 1 protein; metastasis-associated protein MTA1; MTA1; Zg29
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116870, 64520, 9112
Content And Storage: -20°C
Form: Lyophilized
Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.: Q13330, Q62599, Q8K4B0
Gene Symbols: MTA1
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MTA1 (676-696aa ETKRAARRPYKPIALRQSQAL).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MTA1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MTA1
Gene Alias:
metastasis associated 1; metastasis associated gene 1 protein; metastasis-associated protein MTA1; MTA1; Zg29
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116870, 64520, 9112
Content And Storage:
-20°C
Form:
Lyophilized
Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.:
Q13330, Q62599, Q8K4B0
Gene Symbols:
MTA1
Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human MTA1 (676-696aa ETKRAARRPYKPIALRQSQAL).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MTCO1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: mt-Co1
Gene Alias: Co1; coi; cox1; coxi; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase I; mtco1; mt-co1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17708, 26195
Content And Storage: -20°C
Form: Lyophilized
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.: P00397, P05503
Gene Symbols: mt-Co1
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse MTCO1 (501-514aa PYHTFEEPTYVKVK).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MTCO1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
mt-Co1
Gene Alias:
Co1; coi; cox1; coxi; Cytochrome c oxidase polypeptide I; Cytochrome c oxidase subunit 1; cytochrome c oxidase subunit I; mitochondrially encoded cytochrome c oxidase I; mtco1; mt-co1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17708, 26195
Content And Storage:
-20°C
Form:
Lyophilized
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.:
P00397, P05503
Gene Symbols:
mt-Co1
Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse MTCO1 (501-514aa PYHTFEEPTYVKVK).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MUC4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MUC4
Gene Alias: 4933405I11Rik; Ascites sialoglycoprotein; Ascites sialoglycoprotein 1; Ascites sialoglycoprotein 2; ASGP; ASGP1; ASGP-1; ASGP-2; HSA276359; MUC4; MUC-4; mucin 4; mucin 4, ASGP; mucin 4, cell surface associated; mucin 4, tracheobronchial; Mucin4; mucin-4; Mucin-4 alpha chain; Mucin-4 beta chain; Pancreatic adenocarcinoma mucin; pre-sialomucin complex; Psmc; sialomucin ascites sialoglycoprotein-1; sialomucin complex; testis mucin; Tracheobronchial mucin
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 303887, 4585
Content And Storage: -20°C
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: Q63661, Q99102
Gene Symbols: MUC4
Immunogen: E.coli-derived human MUC4 recombinant protein (Position: M1249-D1444).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MUC4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MUC4
Gene Alias:
4933405I11Rik; Ascites sialoglycoprotein; Ascites sialoglycoprotein 1; Ascites sialoglycoprotein 2; ASGP; ASGP1; ASGP-1; ASGP-2; HSA276359; MUC4; MUC-4; mucin 4; mucin 4, ASGP; mucin 4, cell surface associated; mucin 4, tracheobronchial; Mucin4; mucin-4; Mucin-4 alpha chain; Mucin-4 beta chain; Pancreatic adenocarcinoma mucin; pre-sialomucin complex; Psmc; sialomucin ascites sialoglycoprotein-1; sialomucin complex; testis mucin; Tracheobronchial mucin
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
303887, 4585
Content And Storage:
-20°C
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
Q63661, Q99102
Gene Symbols:
MUC4
Immunogen:
E.coli-derived human MUC4 recombinant protein (Position: M1249-D1444).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG