PIPA579716

MYLK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA579716-Each-of-1 In Stock ₹ 41,411.04

PIPA579716 - Each of 1

₹ 41,411.04

In Stock

Quantity

1

Base Price: ₹ 41,411.04

GST (18%): ₹ 7,453.987

Total Price: ₹ 48,865.027

Antigen

MYLK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MYLK

Gene Alias

155 kda myosin light chain kinase homolog; 9530072E15Rik; A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA; The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene.; A930019C19Rik; AAT7; AW489456; kinase related protein; kinase-related protein; KRP; KRP/Telokin; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; mylk; MYLK1; myosin light chain kinase; myosin light chain kinase, smooth muscle; Myosin light chain kinase, smooth muscle, deglutamylated form; myosin, light polypeptide kinase; nmMlck; smMLCK; smooth muscle myosin light chain kinase; smooth muscle myosin light chain kinase (61-kDa active fragment); smooth muscle myosin light chain kinase precursor (EC 2.7.2.37); telokin; unnamed protein product

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

107589, 288057, 4638

Content And Storage

-20°C

Form

Lyophilized

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and no preservative

Gene Accession No.

Q15746, Q6PDN3

Gene Symbols

MYLK

Immunogen

E. coli-derived human MYLK recombinant protein (Position: D1441-D1709).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • MYLK (MLCK) is a serine/threonine kinase that phosphorylates myosin regulatory light chains to assist in the production of contractile activity (myosin-actin interaction)
  • MLCK is responsible for smooth muscle contraction via phosphorylation of a specific serine in the N-terminus of myosin light chains (MLC), an event that facilitates myosin interaction with actin filaments
  • It is a central determinant in the development of vascular permeability and tissue edema formation
  • In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells
  • MLCK acts as a critical participant in signaling sequences that result in fibroblast apoptosis
  • Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific
  • Non-muscle isoform 2 is the dominant splice variant expressed in various tissues
  • The Telokin isoform, which binds calmodulin, has been found in a wide variety of adult and fetal tissues
  • MLCK is probably down-regulated by phosphorylation
  • The protein contains 1 fibronectin type III domain and 9 immunoglobulin-like C2-type domains.

Compare Similar Items

Show Difference

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PIPA579716

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Antigen:
MYLK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYLK

Gene Alias:
155 kda myosin light chain kinase homolog; 9530072E15Rik; A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA; The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene.; A930019C19Rik; AAT7; AW489456; kinase related protein; kinase-related protein; KRP; KRP/Telokin; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; mylk; MYLK1; myosin light chain kinase; myosin light chain kinase, smooth muscle; Myosin light chain kinase, smooth muscle, deglutamylated form; myosin, light polypeptide kinase; nmMlck; smMLCK; smooth muscle myosin light chain kinase; smooth muscle myosin light chain kinase (61-kDa active fragment); smooth muscle myosin light chain kinase precursor (EC 2.7.2.37); telokin; unnamed protein product

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107589, 288057, 4638

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
Q15746, Q6PDN3

Gene Symbols:
MYLK

Immunogen:
E. coli-derived human MYLK recombinant protein (Position: D1441-D1709).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA579718

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Antigen:
Neurocan

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ncan

Gene Alias:
245 kDa early postnatal core glycoprotein; C230035B04; Chondroitin sulfate proteoglycan 3; chondroitin sulfate proteoglycan 3 (neurocan); chondroitin sulfate proteoglycan 3, related sequence; Cspg3; Cspg3-rs; NCAN; NEUR; neurocan; neurocan core protein; neurocan proteoglycan; TGFbeta-induced transcript, brain; Tgfbit

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13004, 1463, 58982

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
O14594, P55066, P55067

Gene Symbols:
Ncan

Immunogen:
A synthetic peptide corresponding to a sequence of human Neurocan (HENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFA).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA579720

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Antigen:
NKp46 (CD335)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NCR1

Gene Alias:
1-Mar; activating receptor 1; Ar1; CD335; hNKp46; Kilr1; KILR-1; LY94; Ly-94; lymphocyte antigen 94; Lymphocyte antigen 94 homolog; lymphocyte antigen 94 homolog (activating NK-receptor; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); mAR-1; MAR1 (mouse activating receptor 1); mNKp46; natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; natural killer cell receptor; Ncr1; NK cell-activating receptor; NK receptor KILR-1; NKACTR; Nkp46; NK-p46; NK-p46); rAR-1; rat-activating receptor 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117547, 17086, 9437

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
O76036, Q8C567, Q9Z0H5

Gene Symbols:
NCR1

Immunogen:
E. coli-derived human NCR1 recombinant protein (Position: Q22-R258).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA579721

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Antigen:
NDRG2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NDRG2

Gene Alias:
AI182517; antidepressant-related protein ADRG123; AU040374; cytoplasmic protein Ndr1; DKFZp781G1938; FLJ25522; Kiaa1248; NDR1-related protein NDR2; Ndr2; NDRG family member 2; NDRG1-related protein; NDRG2; NDRG2var; N-myc downstream regulated 2; N-Myc downstream regulated gene 2; N-myc downstream regulator 2; N-myc downstream-regulated gene 2; N-myc downstream-regulated gene 2 protein; Protein Ndr2; protein NDRG2; Protein Syld709613; SYLD; syld709613 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57447

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
Q9UN36

Gene Symbols:
NDRG2

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human NDRG2 (212-230aa ELIQKYRNIITHAPNLDNI).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG