PIPA579997

SHH Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA579997-Each-of-1 In Stock ₹ 39,870.96

PIPA579997 - Each of 1

₹ 39,870.96

In Stock

Quantity

1

Base Price: ₹ 39,870.96

GST (18%): ₹ 7,176.773

Total Price: ₹ 47,047.733

Antigen

SHH

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Shh

Gene Alias

9530036O11Rik; Dsh; fc83d08; hedgehog; hemimelic extra toes; Hhg1; HHG-1; HLP3; HPE3; Hx; Hxl3; M100081; MCOPCB5; morphogen; shh; Shh N-terminal processed signaling domains; Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; shh.L; shha; ShhN; ShhNC; ShhNp; short digits; SMMCI; sonic hedgehog; sonic hedgehog a; sonic hedgehog homolog; sonic hedgehog L homeolog; sonic hedgehog protein; Sonic hedgehog protein 19 kDa product; Sonic hedgehog protein A; Sonic hedgehog protein A N-product; Sonic hedgehog protein N-product; sonic hedgehog signaling molecule; sonic hedgehog signaling molecule a; sonic-you; syu; TPT; TPTPS; vhh1; vhh-1; wu:fc83d08; XELAEV_18030676mg; Xhh; xshh; X-SHH

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20423, 29499, 6469

Content And Storage

-20°C

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.

Q15465, Q62226, Q63673

Gene Symbols

Shh

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Sonic Hedgehog (203-218aa ATVHLEQGGTKLVKDL).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Sonic Hedgehog (SHH), which is expressed only during embryogenesis, is instrumental in patterning the early embryo
  • It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites
  • Of three human proteins showing sequence and functional similarity to the Sonic Hedgehog protein of Drosophila, this protein is the most similar
  • The protein is made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing
  • More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo
  • Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres
  • HPE is manifested by facial deformities
  • In addition, it is thought that mutations in this gene or in its signalling pathway may be responsible for VACTERL syndrome, which is characterized by vertebral defects, anal atresia, tracheoesophageal fistula with esophageal atresia, radial and renal dysplasia, cardiac anomalies, and limb abnormalities.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA579997

--


Antigen:
SHH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Shh

Gene Alias:
9530036O11Rik; Dsh; fc83d08; hedgehog; hemimelic extra toes; Hhg1; HHG-1; HLP3; HPE3; Hx; Hxl3; M100081; MCOPCB5; morphogen; shh; Shh N-terminal processed signaling domains; Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; shh.L; shha; ShhN; ShhNC; ShhNp; short digits; SMMCI; sonic hedgehog; sonic hedgehog a; sonic hedgehog homolog; sonic hedgehog L homeolog; sonic hedgehog protein; Sonic hedgehog protein 19 kDa product; Sonic hedgehog protein A; Sonic hedgehog protein A N-product; Sonic hedgehog protein N-product; sonic hedgehog signaling molecule; sonic hedgehog signaling molecule a; sonic-you; syu; TPT; TPTPS; vhh1; vhh-1; wu:fc83d08; XELAEV_18030676mg; Xhh; xshh; X-SHH

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20423, 29499, 6469

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
Q15465, Q62226, Q63673

Gene Symbols:
Shh

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human Sonic Hedgehog (203-218aa ATVHLEQGGTKLVKDL).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA579998

--


Antigen:
SIDT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIDT1

Gene Alias:
AW045928; B830021E24Rik; SID1; SID-1; SID1 transmembrane family member 1; SID1 transmembrane family, member 1; SIDT1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54847

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
Q9NXL6

Gene Symbols:
SIDT1

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human SIDT1 (36-52aa RRDPFDAARGADFDHVY).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA579999

--


Antigen:
SIRT7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIRT7

Gene Alias:
MGC126840; MGC126842; NAD-dependent deacetylase sirtuin-7; NAD-dependent protein deacetylase sirtuin-7; NAD-dependent protein deacylase sirtuin-7; regulatory protein SIR2 homolog 7; silent mating type information regulation 2, S.cerevisiae, homolog 7; Sir2l7; SIR2-like protein 7; sir2-related protein type 7; Sirt7; sirtuin 7; sirtuin type 7; Unknown (protein for MGC:142712)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
209011, 303745, 51547

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
B2RZ55, Q8BKJ9, Q9NRC8

Gene Symbols:
SIRT7

Immunogen:
E.coli-derived human SIRT7 recombinant protein (Position: R8-G350).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA580000

--


Antigen:
NTCP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLC10A1

Gene Alias:
bile acid cotransporting polypeptide; cell growth-inhibiting gene 29 protein; GIG29; growth-inhibiting protein 29; hepatic sodium-dependent bile acid transporter; LOW QUALITY PROTEIN: sodium/bile acid cotransporter; MGC128766 protein; Na(+)/bile acid cotransporter; Na(+)/taurocholate transport protein; Na/taurocholate cotransporting polypeptide; NA-dependent cholate transporting protein; Ntcp; Ntcp1; SBACT; Slc10a1; sodium bile acid cotransporting polypeptide; sodium/bile acid cotransporter; sodium/tauro; sodium/taurocholate cotransporter; sodium/taurocholate cotransporting polypeptide; sodium-dependent bile acid cotransporter; sodium-dependent taurocholate cotransporting polypeptide; sodium-taurocholate cotransporting polypeptide; solute carrier family 10 (sodium/bile acid cotransporter family), member 1; solute carrier family 10 (sodium/bile acid cotransporter), member 1; solute carrier family 10 member 1; solute carrier family 10, member 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20493, 24777, 6554

Content And Storage:
-20°C

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.01MG sodium azide

Gene Accession No.:
O08705, P26435, Q14973

Gene Symbols:
SLC10A1

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human SLC10A1 (141-154aa YSRGIYDGDLKDKV).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG