PIPA580036
SMAD1/SMAD5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA580036-Each-of-1 | In Stock | ₹ 39,015.36 |
PIPA580036 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,015.36
GST (18%): ₹ 7,022.765
Total Price: ₹ 46,038.125
Antigen
SMAD1/SMAD5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SMAD1
Gene Alias
1110051M15Rik; AI451355; AI528653; BSP1; BSP-1; dwarfin-A; Dwarfin-C; dwf-A; DWFC; Dwf-C; hSMAD1; hSmad5; JV41; JV4-1; JV5-1; MAD (mothers against decapentaplegic, Drosophila) homolog 1; MAD homolog 1; MAD homolog 5; MAD homolog1 (mothers against decapentaplegic, Drosophila); MAD, mothers against decapentaplegic homolog 1; MAD, mothers against decapentaplegic homolog 5; Madh1; Madh5; Madr1; mad-related protein 1; Mlp1; mMad1; mothers against decapentaplegic homolog 1; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; mothers against DPP homolog 1; mothers against DPP homolog 5; mothers-against-DPP-related 1; Msmad5; MusMLP; OTTHUMP00000223331; SMA- and MAD-related protein 5; SMAD; Smad 1; SMAD 5; SMAD family member 1; SMAD family member 5; SMAD, mothers against DPP homolog 1; SMAD, mothers against DPP homolog 5; SMAD1; SMAD5; TGF-beta signaling protein 1; transforming growth factor-beta signaling protein 1; Transforming growth factor-beta-signaling protein 1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17125, 17129, 25671, 4086, 4090, 59328
Content And Storage
-20°C
Form
Lyophilized
Applications
Western Blot
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.
P70340, P97454, P97588, Q15797, Q99717, Q9R1V3
Gene Symbols
SMAD1, Smad5
Immunogen
A synthetic peptide corresponding to a sequence of human SMAD1/SMAD5 (KRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEK).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- The Smad family of proteins are functioning in the transmission of extracellular signals in the TGF-beta signaling pathway
- Binding of a TGF-beta superfamily ligands to extracellular receptors triggers phosphorylation of Smad2 at a Serine-Serine-Methionine-Serine (SSMS) motif at its C-terminus
- Phosphorylated Smad2 is then able to form a complex with Smad4
- These complexes accumulate in the cell nucleus, where they are directly participating in the regulation of gene expression
- In mammals, eight Smad proteins have been identified to date
- The Smad family of proteins can be divided into three functional groups: the receptor-activated Smads (R-Smads), common mediator Smads (Co-Smads), and the inhibitory Smads (I-Smads)
- The R-Smads are directly phosphorylated by the activated type I receptors on their C-terminal Ser-Ser-X-Ser (SSXS) motif and include Smad1, Smad2, Smad3, Smad5, and Smad8
- Smad2 and Smad3 are phosphorylated in response to TGF-beta and activin, whereas Smad1, Smad5, and Smad8 are phosphorylated in response to BMP (Bone Morphogenetic Protein)
- This C-terminal phosphorylation allows R-Smad binding to Co-Smad, Smad4, and translocation to the nucleus where they regulate TGF-beta target genes
- Smad6 and Smad7 belong to the I-Smad which bind to the type I receptor or Smad4 and block their interaction with R-Smads.
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Antigen: SMAD1/SMAD5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMAD1
Gene Alias: 1110051M15Rik; AI451355; AI528653; BSP1; BSP-1; dwarfin-A; Dwarfin-C; dwf-A; DWFC; Dwf-C; hSMAD1; hSmad5; JV41; JV4-1; JV5-1; MAD (mothers against decapentaplegic, Drosophila) homolog 1; MAD homolog 1; MAD homolog 5; MAD homolog1 (mothers against decapentaplegic, Drosophila); MAD, mothers against decapentaplegic homolog 1; MAD, mothers against decapentaplegic homolog 5; Madh1; Madh5; Madr1; mad-related protein 1; Mlp1; mMad1; mothers against decapentaplegic homolog 1; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; mothers against DPP homolog 1; mothers against DPP homolog 5; mothers-against-DPP-related 1; Msmad5; MusMLP; OTTHUMP00000223331; SMA- and MAD-related protein 5; SMAD; Smad 1; SMAD 5; SMAD family member 1; SMAD family member 5; SMAD, mothers against DPP homolog 1; SMAD, mothers against DPP homolog 5; SMAD1; SMAD5; TGF-beta signaling protein 1; transforming growth factor-beta signaling protein 1; Transforming growth factor-beta-signaling protein 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17125, 17129, 25671, 4086, 4090, 59328
Content And Storage: -20°C
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: P70340, P97454, P97588, Q15797, Q99717, Q9R1V3
Gene Symbols: SMAD1, Smad5
Immunogen: A synthetic peptide corresponding to a sequence of human SMAD1/SMAD5 (KRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEK).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SMAD1/SMAD5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMAD1
Gene Alias:
1110051M15Rik; AI451355; AI528653; BSP1; BSP-1; dwarfin-A; Dwarfin-C; dwf-A; DWFC; Dwf-C; hSMAD1; hSmad5; JV41; JV4-1; JV5-1; MAD (mothers against decapentaplegic, Drosophila) homolog 1; MAD homolog 1; MAD homolog 5; MAD homolog1 (mothers against decapentaplegic, Drosophila); MAD, mothers against decapentaplegic homolog 1; MAD, mothers against decapentaplegic homolog 5; Madh1; Madh5; Madr1; mad-related protein 1; Mlp1; mMad1; mothers against decapentaplegic homolog 1; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; mothers against DPP homolog 1; mothers against DPP homolog 5; mothers-against-DPP-related 1; Msmad5; MusMLP; OTTHUMP00000223331; SMA- and MAD-related protein 5; SMAD; Smad 1; SMAD 5; SMAD family member 1; SMAD family member 5; SMAD, mothers against DPP homolog 1; SMAD, mothers against DPP homolog 5; SMAD1; SMAD5; TGF-beta signaling protein 1; transforming growth factor-beta signaling protein 1; Transforming growth factor-beta-signaling protein 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17125, 17129, 25671, 4086, 4090, 59328
Content And Storage:
-20°C
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
P70340, P97454, P97588, Q15797, Q99717, Q9R1V3
Gene Symbols:
SMAD1, Smad5
Immunogen:
A synthetic peptide corresponding to a sequence of human SMAD1/SMAD5 (KRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEK).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SMAD5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMAD5
Gene Alias: 1110051M15Rik; AI451355; DKFZp781C1895; DKFZp781O1323; dwarfin-C; DWFC; Dwf-C; hSmad5; JV5-1; MAD homolog 5; MAD, mothers against decapentaplegic homolog 5; Madh5; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; mothers against DPP homolog 5; mSmad5; MusMLP; OTTHUMP00000223331; SMA- and MAD-related protein 5; SMAD; SMAD 5; SMAD family member 5; SMAD, mothers against DPP homolog 5; SMAD5
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17129, 4090, 59328
Content And Storage: -20°C
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.: P97454, Q99717, Q9R1V3
Gene Symbols: SMAD5
Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SMAD5 (248-267aa IPQIMPSISSRDVQPVAYEE).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SMAD5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMAD5
Gene Alias:
1110051M15Rik; AI451355; DKFZp781C1895; DKFZp781O1323; dwarfin-C; DWFC; Dwf-C; hSmad5; JV5-1; MAD homolog 5; MAD, mothers against decapentaplegic homolog 5; Madh5; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; mothers against DPP homolog 5; mSmad5; MusMLP; OTTHUMP00000223331; SMA- and MAD-related protein 5; SMAD; SMAD 5; SMAD family member 5; SMAD, mothers against DPP homolog 5; SMAD5
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17129, 4090, 59328
Content And Storage:
-20°C
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal
Gene Accession No.:
P97454, Q99717, Q9R1V3
Gene Symbols:
SMAD5
Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human SMAD5 (248-267aa IPQIMPSISSRDVQPVAYEE).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SMC3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMC3
Gene Alias: Bam; Bamacan; basement membrane chondroitin sulfate proteoglycan; basement membrane-associated chondroitin proteoglycan; BMH; CDLS3; chondroitin sulfate proteoglycan 6; chondroitin sulfate proteoglycan 6 (bamacan); chromosome segregation protein SmcD; Chromosome-associated polypeptide; cspg6; HCAP; im:7142991; mad member-interacting protein 1; Mmip1; SMC protein 3; Smc3; SMC-3; SMC3 protein; SMC3L1; SmcD; structural maintenace of chromosomes 3; structural maintenance of chromosomes 3; structural maintenance of chromosomes protein 3; structural maintenance of chromosomes protein 3-like protein; wu:fb22e01; wu:fc30d07
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13006, 29486, 9126
Content And Storage: -20°C
Form: Lyophilized
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: P97690, Q9CW03, Q9UQE7
Gene Symbols: SMC3
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SMC3 (1178-1216aa ELLESADKFYGVKFRNKVSHIDVITAEMAKDFVEDDTTH).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SMC3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMC3
Gene Alias:
Bam; Bamacan; basement membrane chondroitin sulfate proteoglycan; basement membrane-associated chondroitin proteoglycan; BMH; CDLS3; chondroitin sulfate proteoglycan 6; chondroitin sulfate proteoglycan 6 (bamacan); chromosome segregation protein SmcD; Chromosome-associated polypeptide; cspg6; HCAP; im:7142991; mad member-interacting protein 1; Mmip1; SMC protein 3; Smc3; SMC-3; SMC3 protein; SMC3L1; SmcD; structural maintenace of chromosomes 3; structural maintenance of chromosomes 3; structural maintenance of chromosomes protein 3; structural maintenance of chromosomes protein 3-like protein; wu:fb22e01; wu:fc30d07
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13006, 29486, 9126
Content And Storage:
-20°C
Form:
Lyophilized
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
P97690, Q9CW03, Q9UQE7
Gene Symbols:
SMC3
Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human SMC3 (1178-1216aa ELLESADKFYGVKFRNKVSHIDVITAEMAKDFVEDDTTH).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SMC6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMC6
Gene Alias: 2810489L22Rik; 3830418C19Rik; AA990493; AU018782; AW742439; hSMC6; Kiaa4103; mKIAA4103; mSMC6; SMC protein 6; Smc6; SMC-6; SMC6 structural maintenance of chromosomes 6-like 1; SMC6L1; structural maintenance of chromosomes 6; structural maintenance of chromosomes protein 6; Structural maintenance of chromosomes protein 6-like protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 313961, 67241, 79677
Content And Storage: -20°C
Form: Lyophilized
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: Q924W5, Q96SB8
Gene Symbols: SMC6
Immunogen: E. coli-derived human SMC6L1 recombinant protein (Position: D205-E443).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SMC6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMC6
Gene Alias:
2810489L22Rik; 3830418C19Rik; AA990493; AU018782; AW742439; hSMC6; Kiaa4103; mKIAA4103; mSMC6; SMC protein 6; Smc6; SMC-6; SMC6 structural maintenance of chromosomes 6-like 1; SMC6L1; structural maintenance of chromosomes 6; structural maintenance of chromosomes protein 6; Structural maintenance of chromosomes protein 6-like protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
313961, 67241, 79677
Content And Storage:
-20°C
Form:
Lyophilized
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
Q924W5, Q96SB8
Gene Symbols:
SMC6
Immunogen:
E. coli-derived human SMC6L1 recombinant protein (Position: D205-E443).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG