PIPA580475

Chk1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA580475-Each-of-1 In Stock ₹ 30,801.60

PIPA580475 - Each of 1

₹ 30,801.60

In Stock

Quantity

1

Base Price: ₹ 30,801.60

GST (18%): ₹ 5,544.288

Total Price: ₹ 36,345.888

Antigen

Chk1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Chek1

Gene Alias

C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1111

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

1.05 mg/mL

Formulation

PBS with no preservative; pH 7

Gene Accession No.

O14757

Gene Symbols

Chek1

Immunogen

Recombinant Human Chk1 Protein (Met1-Thr476)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Human Chk1
  • CHEK1 (CHK1) is a serine/threonine protein kinase involved in preventing replication when DNA integrity is compromised
  • CHK1 is a key mediator in the DNA damage-induced checkpoint network
  • CHK1 is an evolutionarily conserved protein kinase that functions to ensure genomic integrity upon genotoxic stress
  • When the G2 or S checkpoint is abrogated by the inhibition of CHK1, p53-deficient cancer cells undergo mitotic catastrophe and eventually apoptosis, whereas normal cells are still arrested in the G1 phase
  • Thus, CHK1 inhibitors can preferentially potentiate the efficacy of DNA damaging agents in cancer cells, and Chk1 is an attractive therapeutic target for cancer treatment, especially since approximately 50% of all human cancers are p53-deficient.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA580475

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Antigen:
Chk1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chek1

Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1111

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
1.05 mg/mL

Formulation:
PBS with no preservative; pH 7

Gene Accession No.:
O14757

Gene Symbols:
Chek1

Immunogen:
Recombinant Human Chk1 Protein (Met1-Thr476)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA580476

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Antigen:
Creatine Kinase BB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CKB

Gene Alias:
Bck; B-CK; brain creatine kinase; Ck3; Ck-3; CKB; Ckbb; Ckbr; CPK-B; creatine kinase B; creatine kinase B chain; creatine kinase brain; creatine kinase brain-type; Creatine kinase B-type; creatine kinase, brain; creatine kinase-B; Creatine phosphokinase B-type; Creatine phosphokinase M-type; epididymis luminal protein 211; epididymis secretory protein Li 29; HEL-211; HEL-S-29

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1152

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P12277

Gene Symbols:
CKB

Immunogen:
Recombinant Human CKB/Creatine kinase B type protein (Pro2-Lys381)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA580477

--


Antigen:
CIDEA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CIDEA

Gene Alias:
AW212747; cell death activator CIDE-A; Cell death-inducing DFFA-like effector A; cell death-inducing DNA fragmentation factor, alpha subunit-like effector A; cide a; Cidea; CIDE-A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1149

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O60543

Gene Symbols:
CIDEA

Immunogen:
A synthetic peptide corresponding to the C-terminus of the Human CIDEA

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA580478

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Antigen:
Creatine Kinase MB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ckb

Gene Alias:
Bck; B-CK; Brain creatine kinase; CK MB; Ck3; Ck-3; CKB; Ckbb; Ckbr; Ckm; CKMM; CPK-B; CPK-M; creatine kinase B; creatine kinase B chain; creatine kinase brain; creatine kinase brain-type; Creatine kinase B-type; creatine kinase M chain; Creatine kinase M-type; creatine kinase, brain; creatine kinase, M-type; creatine kinase, muscle; creatine kinase-B; creatine kinase-M; Creatine phosphokinase B-type; Creatine phosphokinase M-type; epididymis luminal protein 211; epididymis secretory protein Li 29; HEL-211; HEL-S-29; MCK; M-CK

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1152, 1158

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P06732, P12277

Gene Symbols:
Ckb, CKM

Immunogen:
Recombinant Human CKM/CK-MM Protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG