PIPA580598

IRE1 alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA580598-Each-of-1 In Stock ₹ 30,801.60

PIPA580598 - Each of 1

₹ 30,801.60

In Stock

Quantity

1

Base Price: ₹ 30,801.60

GST (18%): ₹ 5,544.288

Total Price: ₹ 36,345.888

Antigen

IRE1 alpha

Classification

Polyclonal

Formulation

PBS with no preservative

Gene Accession No.

O75460

Gene Symbols

ERN1

Immunogen

Recombinant Human ERN1/IRE1 Protein (Pro465-Leu977)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Gene

ERN1

Gene Alias

9030414B18Rik; AI225830; C85377; endoplasmic reticulum (ER) to nucleus signalling 1; endoplasmic reticulum to nucleus signaling 1; endoplasmic reticulum to nucleus signalling 1; endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signalling 1; ERN1; FLJ30999; hIRE1p; inositol-requiring 1; inositol-requiring 1 alpha; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; IRE1a antibody; Ire1alpha; Ire1-alpha; Ire1p; IRE1p antibody; MGC163277; MGC163279; protein kinase/endoribonuclease; RGD1559716; Serine/threonine-protein kinase; Serine/threonine-protein kinase/endoribonuclease IRE1; serine/threonine-protein kinase/endoribonuclease IRE1-like

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

2081

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Human ERN1/IRE1
  • ERN1 serine/threonine kinase or endoplasmic reticulum to nucleus signaling 1 is the ER to nucleus signaling 1 protein, a human homologue of the yeast Ire1 gene product which possesses intrinsic kinase activity and an endoribonuclease activity and it is important in endoplasmic reticulum-based stress signals
  • ERN1 controls IRE1 proteolysis in mammalian cells
  • ERN1 has a critical function in extraembryonic cells that is essential for fetal viability
  • Specifically, IRE1 acts as the sensor of unfolded proteins in the ER that initiates transmittance of the unfolded protein signal from the ER to the nucleus by splicing XBP1 mRNA converting it into a potent unfolded-protein response transcriptional activator
  • Null mutants are viable, but IRE1 is essential for viability under stress conditions that cause unfolded proteins to accumulate in the ER
  • Depletion of IRE1p through the expression of a dominant negative form of IRE1p has no effect on transfected cells, but cell death via apoptosis occurs under stress conditions that cause unfolded proteins to accumulate in the ER.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA580598

--


Antigen:
IRE1 alpha

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
O75460

Gene Symbols:
ERN1

Immunogen:
Recombinant Human ERN1/IRE1 Protein (Pro465-Leu977)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Gene:
ERN1

Gene Alias:
9030414B18Rik; AI225830; C85377; endoplasmic reticulum (ER) to nucleus signalling 1; endoplasmic reticulum to nucleus signaling 1; endoplasmic reticulum to nucleus signalling 1; endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signalling 1; ERN1; FLJ30999; hIRE1p; inositol-requiring 1; inositol-requiring 1 alpha; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; IRE1a antibody; Ire1alpha; Ire1-alpha; Ire1p; IRE1p antibody; MGC163277; MGC163279; protein kinase/endoribonuclease; RGD1559716; Serine/threonine-protein kinase; Serine/threonine-protein kinase/endoribonuclease IRE1; serine/threonine-protein kinase/endoribonuclease IRE1-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2081

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PIPA580600

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Antigen:
ESAM

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
Q96AP7

Gene Symbols:
ESAM

Immunogen:
Recombinant Human ESAM protein (Met1-Ala248)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Gene:
ESAM

Gene Alias:
2310008D05Rik; endothelial cell adhesion molecule; endothelial cell-selective adhesion molecule; endothelial cell-specific adhesion molecule; Esam; Esam1; HUEL (C4orf1)-interacting protein; LP4791 protein; UNQ220/PRO246; W117m

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
90952

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PIPA580602

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Antigen:
ETV5

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P41161

Gene Symbols:
ETV5

Immunogen:
A synthetic peptide corresponding to the center region of the Human ETV5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Gene:
ETV5

Gene Alias:
1110005E01Rik; 8430401F14Rik; ERM; ETS translocation variant 5; ets variant 5; ets variant gene 5; ets variant gene 5 (ets-related molecule); ets-related molecule; ets-related protein ERM; ETV5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2119

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Antigen:
Ezrin

Classification:
Polyclonal

Formulation:
PBS with no preservative

Gene Accession No.:
P15311

Gene Symbols:
Ezr

Immunogen:
Recombinant Human Ezrin/villin 2 protein (Pro2-Leu586)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
Ezr

Gene Alias:
AW146364; CVIL; CVL; Cytovillin; cytovillin 2; DKFZp762H157; epididymis secretory protein Li 105; ezr; ezr.L; ezr.S; EZRI; Ezrin; ezrin L homeolog; ezrin L homeolog; ezrin S homeolog; FLJ26216; HEL-S-105; MGC1584; p81; R75297; VIL2; villin 2; villin 2 (ezrin); villin-2; XELAEV_18027043mg

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7430

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid