PIPA581203

CD18 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA581203-Each-of-1 In Stock ₹ 30,801.60

PIPA581203 - Each of 1

₹ 30,801.60

In Stock

Quantity

1

Base Price: ₹ 30,801.60

GST (18%): ₹ 5,544.288

Total Price: ₹ 36,345.888

Antigen

CD18

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ITGB2

Gene Alias

2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B,

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

16414

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P11835

Gene Symbols

ITGB2

Immunogen

A synthetic peptide corresponding to the N-terminus of the Human CD18/Integrin beta 2/ITGB2

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Mouse CD18
  • CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leucocytes
  • CD18 can combine with integrin molecules CD11a-c to form heterodimers at the cell surface, and these heterodimers are known to participate in the process of cell adhesion as well as cell-surface mediated signaling
  • CD18 forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18)
  • In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits, and these integrins are essential for proper leukocyte migration, mediating intercellular contacts
  • Absence of CD18 leads to leukocyte adhesion deficiency-1, severe reduction of CD18 expression leads to the development of a psoriasiform skin disease
  • CD18 is also a target of Mannheimia (Pasteurella) haemolytica leukotoxin and is sufficient to mediate leukotoxin-mediated cytolysis
  • Defects in the CD18 gene are the cause of leukocyte adhesion deficiency type I (LAD1)
  • Two transcript variants encoding the CD18 protein have been identified.

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Show Difference

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PIPA581203

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Antigen:
CD18

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITGB2

Gene Alias:
2E6; AI528527; antigen CD18; B-2 integrin; CD18; CD18 leukocyte adhesion molecule; CD18 subunit; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; integrin beta 2; integrin beta chain, beta 2; integrin beta-2; integrin subunit beta 2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGB2; LAD; LCAMB; Leu-CAM receptor; leukocyte cell adhesion molecule CD18; leukocyte surface protein; leukocyte-associated antigens CD18/11A, CD18/11B,

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16414

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P11835

Gene Symbols:
ITGB2

Immunogen:
A synthetic peptide corresponding to the N-terminus of the Human CD18/Integrin beta 2/ITGB2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA581204

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Antigen:
CD104

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITGB4

Gene Alias:
AA407042; C230078O20; CD antigen CD104; CD104; CD104 antigen; GP150; integrin beta 4; integrin beta-4; integrin subunit beta 4; integrin, beta 4; Itgb4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3691

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P16144

Gene Symbols:
ITGB4

Immunogen:
A synthetic peptide corresponding to the N-terminus of the Human Integrin beta 4/CD104

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA581208

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Antigen:
Cytokeratin 6A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KRT6A

Gene Alias:
2310016L08Rik, 60-kDa keratin, CK6A, CK-6A, CK6C, CK-6C, CK6D, CK-6D, CK-6E, cytokeratin 6A, cytokeratin 6C, cytokeratin 6D, cytokeratin-6A, cytokeratin-6C, Cytokeratin-6D, cytokeratin-6E, Hom s 5, K6A, K6a keratin, K6C, K6D, kamp-keratin derived antimicrobial peptide, KDAMP, Ker2, keratin 6A, keratin 6A, , type II, keratin 6A, type II, keratin complex 2, basic, gene 6a, keratin complex 2, basic, gene 6c, keratin complex 2, gene 6a, keratin K6, keratin K6h, keratin, epidermal type II, K6A, keratin, type II cytoskeletal 6A, keratin, type II cytoskeletal 6C, Keratin-6A, keratin-6-alpha, keratin-6C, Krt2-6, Krt2-6a, Krt2-6c, Krt6, KRT6A, KRT6C, KRT6D, LOC683313, mK6[a], MK6a, mK6-alpha, PC3, similar to keratin complex 2, basic, gene 6a, type-II keratin Kb12, type-II keratin Kb6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3853

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
P02538

Gene Symbols:
KRT6A

Immunogen:
A synthetic peptide corresponding to the center region of the Human KRT6A/Cytokeratin6A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA581209

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Antigen:
KRT79

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KRT79

Gene Alias:
BC031593; CK-79; cytokeratin-79; K6L; K79; KB38; keratin 6L; keratin 79; keratin 79, type II; keratin, type II cytoskeletal 79; Keratin-6L; Keratin-6-like; keratin-79; KRT6L; KRT79; Type-II keratin Kb38

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
338785

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.03% ProClin 300; pH 7

Gene Accession No.:
Q5XKE5

Gene Symbols:
KRT79

Immunogen:
A synthetic peptide corresponding to the center region of the Human KRT6L/KRT79

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG