PIPA581304

CD45 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA581304-Each-of-1 In Stock ₹ 30,801.60

PIPA581304 - Each of 1

₹ 30,801.60

In Stock

Quantity

1

Base Price: ₹ 30,801.60

GST (18%): ₹ 5,544.288

Total Price: ₹ 36,345.888

Antigen

CD45

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PTPRC

Gene Alias

B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5788

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P08575

Gene Symbols

PTPRC

Immunogen

A synthetic peptide corresponding to the C-terminus of the Human CD45/PTPRC

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This product is preservative free
  • It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%)
  • This antibody has specificity for Human CD45
  • CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) ubiquitously expressed in all nucleated hematopoietic cells, comprising approximately 10% of all surface proteins in lymphocytes
  • CD45 is absent on non-hematopoietic cell lines, normal and malignant, non-hematopoietic tissues
  • CD45 glycoprotein is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases
  • CD45 protein exists as multiple isoforms as a result of alternative splicing, differ in their extracellular domains but share identical transmembrane and cytoplasmic domains
  • CD45RA is an isoform of the CD45 complex and has restricted expression between different subtypes of lymphoid cells
  • CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell
  • CD45 has been shown to be an essential regulator of T- and B-cell antigen receptor signaling and suppresses JAK kinases to regulate cytokine receptor signaling
  • CD45 is also important in promoting cell survival by modulating integrin-mediated signal transduction pathway, DNA fragmentation during apoptosis and inhibition or upregulation of various immunological functions.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA581304

--


Antigen:
CD45

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPRC

Gene Alias:
B220; cd45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; Lca; L-CA; leucocyte common antigen; leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; leukocyte common antigen, CD45; loc; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase lambda; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; Ptprc; Receptor-type tyrosine-protein phosphatase C; RT7; T200; T200 glycoprotein; T200 leukocyte common antigen; T220 and B220

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Immunogen:
A synthetic peptide corresponding to the C-terminus of the Human CD45/PTPRC

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA581305

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Antigen:
UBE4A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ube4a

Gene Alias:
4732444G18Rik; 9930123J21Rik; Ab2-232; E4; KIAA0126; RING-type E3 ubiquitin transferase E4 A; UBE4A; Ubiquitin conjugation factor E4 A; ubiquitination factor E4A; ubiquitination factor E4A (UFD2 homolog, yeast); ubiquitination factor E4A, UFD2 homolog; UBOX2; UFD2; UFD2b

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9354

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q14139

Gene Symbols:
Ube4a

Immunogen:
A synthetic peptide corresponding to the N-terminus of the Human UBE4A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA581306

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Antigen:
GFR alpha-3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gfra3

Gene Alias:
GDNF family receptor alpha 3; GDNF family receptor alpha-3; GDNF receptor alpha-3; GDNF-family receptor alpha 3; GDNFR3; GDNFR-alpha-3; GFR alpha-3; GFRA3; GFRalpha3; GFR-alpha-3; glial cell line derived neurotrophic factor family receptor alpha 3; glial cell line-derived neurotrophic factor receptor alpha-3; GPI-linked receptor; UNQ339/PRO538/PRO3664; Y15110

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
14587

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
O35118

Gene Symbols:
Gfra3

Immunogen:
A synthetic peptide corresponding to the center region of the Mouse GFRA3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA581307

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Antigen:
HNF6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ONECUT1

Gene Alias:
D9Ertd423e; hepatic nuclear factor 6; hepatocyte nuclear factor 6; hepatocyte nuclear factor 6 alpha; hepatocyte nuclear factor 6, alpha; Hfh12; HNF-3/forkhead homolog 12; hnf6; HNF-6; Hnf6a; HNF-6a; Hnf6b; Oc1; OC-1; One cut domain family member 1; one cut domain, family member 1; one cut domain, family member 1, like; one cut homeobox 1; Onecut1; onecut-1 isoform a; onecut-1 isoform b; onecut1 protein; onecut1l; transcription factor; hepatocyte nuclear factor 6; hnf-6; zgc:65904; zgc:77450

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3175

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
Q9UBC0

Gene Symbols:
ONECUT1

Immunogen:
A synthetic peptide corresponding to the C-terminus of the Human ONECUT1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG