PIPA582487

HLA-DQB1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA582487-Each-of-1 In Stock ₹ 47,015.22

PIPA582487 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

HLA-DQB1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HLA-DQB1

Gene Alias

CELIAC1; DQ beta 1; HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1; lymphocyte antigen; major histocompatibility complex, class II, DQ beta 1; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta

Host Species

Rabbit

Purification Method

Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3119

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.05 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

P01920

Gene Symbols

HLA-DQB1

Immunogen

Recombinant protein corresponding to Human HLA-DQB1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: RPDAEYWNSQ KEVLEGTRAE LDTVCRHNYE VAFRGILQRR VEPTVTISPS RTEALNHHNL LVCSVT HLA-DRB1 belongs to the HLA class II beta chain paralogs
  • The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane
  • It plays a central role in the immune system by presenting peptides derived from extracellular proteins
  • Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages)
  • The beta chain is approximately 26-28 kDa
  • It is encoded by 6 exons
  • Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail
  • Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities
  • Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
  • DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5
  • DRB1 is present in all individuals
  • Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5
  • There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA582487

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Antigen:
HLA-DQB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLA-DQB1

Gene Alias:
CELIAC1; DQ beta 1; HLA class II antigen; HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-DQB; HLA-DQB1; HLA-DRB1; IDDM1; lymphocyte antigen; major histocompatibility complex, class II, DQ beta 1; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II HLA-DQ beta glycoprotein; MHC class2 antigen; MHC DQ beta

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3119

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P01920

Gene Symbols:
HLA-DQB1

Immunogen:
Recombinant protein corresponding to Human HLA-DQB1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA582488

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Antigen:
SLITRK5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SLITRK5

Gene Alias:
2610019D03Rik; bA364G4.2; KIAA0918; leucine rich repeat containing 11; leucine-rich repeat-containing protein 11; LRRC11; SLIT and NTRK like family member 5; SLIT and NTRK-like family, member 5; SLIT and NTRK-like protein 5; slit and trk like gene 5; Slitrk5

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26050

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O94991

Gene Symbols:
SLITRK5

Immunogen:
Recombinant protein corresponding to Human SLITRK5

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA582489

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Antigen:
CMTM3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CMTM3

Gene Alias:
9430096L06Rik; AI413895; BNAS2; chemokine-like factor super family 3; chemokine-like factor superfamily member 3; CKLF like MARVEL transmembrane domain containing 3; CKLF-like MARVEL transmembrane domain containing 3; CKLF-like MARVEL transmembrane domain-containing protein 3; CKLFSF3; CMTM3

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
123920

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96MX0

Gene Symbols:
CMTM3

Immunogen:
Recombinant protein corresponding to Human CMTM3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA582490

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Antigen:
CD223

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LAG3

Gene Alias:
Activation-induced cytidine deaminase-linked autoimmunity protein; Aida; CD223; FDC; LAG3; LAG-3; Ly66; lymphocyte activating 3; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Secreted lymphocyte activation gene 3 protein; sLAG 3; sLAG3; sLAG-3; soluble LAG 3lymphocyte activating 3; soluble LAG3

Host Species:
Rabbit

Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3902

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P18627

Gene Symbols:
LAG3

Immunogen:
Recombinant protein corresponding to Human LAG3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG