CD8 alpha Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA583385-Each-of-1 | In Stock | ₹ 51,336.00 |
PIPA583385 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,336.00
GST (18%): ₹ 9,240.48
Total Price: ₹ 60,576.48
Antigen
CD8 alpha
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CD8B
Gene Alias
BB154331, CD8, CD8 alpha, CD8 alpha chain, CD8 alpha chain precursor, CD8 antigen, CD8 antigen 32 kDa chain, CD8 antigen 37 kDa chain, CD8 antigen alpha polypeptide, CD8 antigen alpha protein, CD8 antigen alpha protein precursor, CD8 antigen alpha-chain, CD8 antigen beta polypeptide, CD8 antigen beta polypeptide precursor, CD8 antigen beta-chain, CD8 antigen, alpha chain, CD8 antigen, alpha polypeptide, CD8 antigen, alpha polypeptide (p32), CD8 antigen, alpha-chain, CD8 antigen, beta chain, CD8 antigen, beta chain 1, CD8 antigen, beta polypeptide, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta-chain, CD8 beta, CD8 beta chain, CD8 beta-2, CD8a, CD8A antigen alpha, CD8a molecule, CD8A, T-cell surface glycoprotein, CD8alpha, CD8B, CD8b antigen, CD8b molecule, CD8b molecule pseudogene, Cd8b1, CD8beta, CD8BP, fCD8, LEU2, Leu-2, Leu2 T-lymphocyte antigen, leu-2a, Ly-2, LY3, Ly-3, Ly-35, Ly-B, Ly-C, Lymphocyte antigen 3, Lyt2, Lyt-2, Lyt-2.1 lymphocyte differentiation antigen (AA at 100), Lyt3, Lyt-3, MAL, membrane glycoprotein, membrane protein, OKT8 T-cell antigen, OX-8 membrane antigen, p32, P37, RHACD8-4, T cell co-receptor, T lymphocyte surface glycoprotein beta chain, T8 T-cell antigen, T-cell antigen Leu2, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein Lyt-2, T-cell surface glycoprotein Lyt-3, T-cell surface molecule, T-lymphocyte differentiation antigen T8/Leu-2, type I transmembrane glycoprotein
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
925, 926
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.30 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P01732, P10966
Gene Symbols
Cd8a, CD8B
Immunogen
Recombinant protein corresponding to Human CD8A
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: AASPTFLLYL SQNKPKAAEG LDTQRFSGKR LGDTFVLTLS DFRRENEGYY FCSALSNSIM YFSHFVPVFL PAKPTTTPAP RPPT Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation
- CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules
- CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I
- CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha
- Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation
- Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells
- Differentiation of naive CD8+ T cells into CTLs is strongly enhanced by IL-2, IL-12 and TGF-beta1.
Compare Similar Items
Show Difference
Antigen: CD8 alpha
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CD8B
Gene Alias: BB154331, CD8, CD8 alpha, CD8 alpha chain, CD8 alpha chain precursor, CD8 antigen, CD8 antigen 32 kDa chain, CD8 antigen 37 kDa chain, CD8 antigen alpha polypeptide, CD8 antigen alpha protein, CD8 antigen alpha protein precursor, CD8 antigen alpha-chain, CD8 antigen beta polypeptide, CD8 antigen beta polypeptide precursor, CD8 antigen beta-chain, CD8 antigen, alpha chain, CD8 antigen, alpha polypeptide, CD8 antigen, alpha polypeptide (p32), CD8 antigen, alpha-chain, CD8 antigen, beta chain, CD8 antigen, beta chain 1, CD8 antigen, beta polypeptide, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta-chain, CD8 beta, CD8 beta chain, CD8 beta-2, CD8a, CD8A antigen alpha, CD8a molecule, CD8A, T-cell surface glycoprotein, CD8alpha, CD8B, CD8b antigen, CD8b molecule, CD8b molecule pseudogene, Cd8b1, CD8beta, CD8BP, fCD8, LEU2, Leu-2, Leu2 T-lymphocyte antigen, leu-2a, Ly-2, LY3, Ly-3, Ly-35, Ly-B, Ly-C, Lymphocyte antigen 3, Lyt2, Lyt-2, Lyt-2.1 lymphocyte differentiation antigen (AA at 100), Lyt3, Lyt-3, MAL, membrane glycoprotein, membrane protein, OKT8 T-cell antigen, OX-8 membrane antigen, p32, P37, RHACD8-4, T cell co-receptor, T lymphocyte surface glycoprotein beta chain, T8 T-cell antigen, T-cell antigen Leu2, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein Lyt-2, T-cell surface glycoprotein Lyt-3, T-cell surface molecule, T-lymphocyte differentiation antigen T8/Leu-2, type I transmembrane glycoprotein
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 925, 926
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.30 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P01732, P10966
Gene Symbols: Cd8a, CD8B
Immunogen: Recombinant protein corresponding to Human CD8A
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen: DDX4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DDX4
Gene Alias: ATP-dependent RNA helicase DDX4, AV206478, Cvh, Ddx4, D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 4, DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 4, DEAD (Asp-Glu-Ala-Asp) box polypeptide 4, DEAD box polypeptide 4, DEAD box protein 4, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4, DEAD-box helicase 4, MGC111074, Mvh, mvh / m'vasa, probable ATP-dependent RNA helicase DDX4, putative ATP-dependent RNA helicase DDX4, RVLG, VASA, Vasa homolog, vasa-like gene protein
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54514
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q9NQI0
Gene Symbols: DDX4
Immunogen: Recombinant protein corresponding to Human DDX4
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen: DDX4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DDX4
Gene Alias: ATP-dependent RNA helicase DDX4; AV206478; Cvh; Ddx4; D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 4; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 4; DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; DEAD box polypeptide 4; DEAD box protein 4; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4; DEAD-box helicase 4; MGC111074; Mvh; mvh / m'vasa; probable ATP-dependent RNA helicase DDX4; putative ATP-dependent RNA helicase DDX4; RVLG; VASA; Vasa homolog; vasa-like gene protein
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54514
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9NQI0
Gene Symbols: DDX4
Immunogen: Recombinant protein corresponding to Human DDX4
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
