PIPA583451
LATS2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA583451-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA583451 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
LATS2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LATS2
Gene Alias
4932411G09Rik, AV277261, AW228608, h-warts, Kinase phosphorylated during mitosis protein, KPM, large tumor suppressor 2, large tumor suppressor homolog 2, large tumor suppressor kinase 2, large tumor suppressor, homolog 2, LATS (large tumor suppressor, Drosophila) homolog 2, LATS, large tumor suppressor, homolog 2, LATS2, serine/threonine kinase KPM, serine/threonine-protein kinase kpm, Serine/threonine-protein kinase LATS2, si:ch211-173o4.2, Warts-like kinase
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26524
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.20 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
Q9NRM7
Gene Symbols
LATS2
Immunogen
Recombinant protein corresponding to Human LATS2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: HLLLRSKSEQ YDLDSLCAGM EQSLRAGPNE PEGGDKSRKS AKGDKGGKDK KQIQTSPVPV RKNSRDEEKR LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family
- LATS2 interacts with a negative regulator of p53 and function in a positive feedback loop with p53 that responds to cytoskeleton damage and this interaction provokes centrosome/mitotic apparatus dysfunction
- LATS2 plays an essential role in the maintenance of mitotic fidelity and genomic integrity
- LATS2 plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
- The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
- Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration
- It negatively regulates G1/S transition by down-regulating cyclin E/CDK2 kinase activity.
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Antigen: LATS2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LATS2
Gene Alias: 4932411G09Rik, AV277261, AW228608, h-warts, Kinase phosphorylated during mitosis protein, KPM, large tumor suppressor 2, large tumor suppressor homolog 2, large tumor suppressor kinase 2, large tumor suppressor, homolog 2, LATS (large tumor suppressor, Drosophila) homolog 2, LATS, large tumor suppressor, homolog 2, LATS2, serine/threonine kinase KPM, serine/threonine-protein kinase kpm, Serine/threonine-protein kinase LATS2, si:ch211-173o4.2, Warts-like kinase
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26524
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.20 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q9NRM7
Gene Symbols: LATS2
Immunogen: Recombinant protein corresponding to Human LATS2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
LATS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LATS2
Gene Alias:
4932411G09Rik, AV277261, AW228608, h-warts, Kinase phosphorylated during mitosis protein, KPM, large tumor suppressor 2, large tumor suppressor homolog 2, large tumor suppressor kinase 2, large tumor suppressor, homolog 2, LATS (large tumor suppressor, Drosophila) homolog 2, LATS, large tumor suppressor, homolog 2, LATS2, serine/threonine kinase KPM, serine/threonine-protein kinase kpm, Serine/threonine-protein kinase LATS2, si:ch211-173o4.2, Warts-like kinase
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26524
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.20 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q9NRM7
Gene Symbols:
LATS2
Immunogen:
Recombinant protein corresponding to Human LATS2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: HEF1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NEDD9
Gene Alias: Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4739
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q14511
Gene Symbols: NEDD9
Immunogen: Recombinant protein corresponding to Human NEDD9
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HEF1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NEDD9
Gene Alias:
Cas scaffolding protein family member 2; CAS2; CASL; CAS-L; cas-like docking; CASS2; Crk-associated substrate lymphocyte-specific protein; Crk-associated substrate related protein Cas-L; CRK-associated substrate-related protein; dJ49G10.2; dJ761I2.1; Enhancer of filamentation 1; Enhancer of filamentation 1 p55; HEF1; mEF1; Nedd9; NEDD-9; Neural precursor cell expressed developmentally down-regulated protein 9; neural precursor cell expressed, developmentally down-regulated 9; neural precursor cell expressed, developmentally down-regulated gene 9; p105; p130Cas-related protein; renal carcinoma antigen NY-REN-12
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4739
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q14511
Gene Symbols:
NEDD9
Immunogen:
Recombinant protein corresponding to Human NEDD9
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: STIP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STIP1
Gene Alias: epididymis secretory sperm binding protein Li 94n, HEL-S-94n, HOP, hsc70/Hsp90-organizing protein, Hsp70/Hsp90 organizing protein, Hsp70/Hsp90-organizing protein, IEF SSP 3521, IEF-SSP-3521, mSTI1, NY-REN-11 antigen, P60, Renal carcinoma antigen NY-REN-11, STI1, STI1L, Stip1, stress induced phosphoprotein 1, stress-induced phosphoprotein 1, stress-induced-phosphoprotein 1, stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein), stress-inducible protein, transformation-sensitive protein IEF SSP 3521
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10963
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P31948
Gene Symbols: STIP1
Immunogen: Recombinant protein corresponding to Human STIP1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
STIP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STIP1
Gene Alias:
epididymis secretory sperm binding protein Li 94n, HEL-S-94n, HOP, hsc70/Hsp90-organizing protein, Hsp70/Hsp90 organizing protein, Hsp70/Hsp90-organizing protein, IEF SSP 3521, IEF-SSP-3521, mSTI1, NY-REN-11 antigen, P60, Renal carcinoma antigen NY-REN-11, STI1, STI1L, Stip1, stress induced phosphoprotein 1, stress-induced phosphoprotein 1, stress-induced-phosphoprotein 1, stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing protein), stress-inducible protein, transformation-sensitive protein IEF SSP 3521
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10963
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P31948
Gene Symbols:
STIP1
Immunogen:
Recombinant protein corresponding to Human STIP1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: DNM1L
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DNM1L
Gene Alias: 6330417M19Rik, AI450666, C-terminal region, Dlp1, dnm1l, Dnm1p/Vps1p-like protein, Dnml1, Dnmlp1, Drp1, DVLP, DYMPLE, dynamin 1 like, dynamin 1-like, dynamin family member proline-rich carboxyl-terminal domain less, Dynamin-1-like protein, Dynamin-1-like protein-like protein, Dynamin-like protein, dynamin-like protein 1, dynamin-like protein 4, Dynamin-like protein IV, dynamin-related protein 1, DYNIV 11, DYNIV-11, EC 3.6.5.5, EGK_03514, EMPF, FLJ41912, HDYNIV, N-terminal region, python, similar to dynamin 1-like, VPS1, zgc:66163
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10059
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: O00429
Gene Symbols: DNM1L
Immunogen: Recombinant protein corresponding to Human DNM1L
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
DNM1L
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DNM1L
Gene Alias:
6330417M19Rik, AI450666, C-terminal region, Dlp1, dnm1l, Dnm1p/Vps1p-like protein, Dnml1, Dnmlp1, Drp1, DVLP, DYMPLE, dynamin 1 like, dynamin 1-like, dynamin family member proline-rich carboxyl-terminal domain less, Dynamin-1-like protein, Dynamin-1-like protein-like protein, Dynamin-like protein, dynamin-like protein 1, dynamin-like protein 4, Dynamin-like protein IV, dynamin-related protein 1, DYNIV 11, DYNIV-11, EC 3.6.5.5, EGK_03514, EMPF, FLJ41912, HDYNIV, N-terminal region, python, similar to dynamin 1-like, VPS1, zgc:66163
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10059
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
O00429
Gene Symbols:
DNM1L
Immunogen:
Recombinant protein corresponding to Human DNM1L
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG