PIPA583857
TMP21 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA583857-Each-of-1 | In Stock | ₹ 50,309.28 |
PIPA583857 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,309.28
GST (18%): ₹ 9,055.67
Total Price: ₹ 59,364.95
Antigen
TMP21
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TMED10
Gene Alias
1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; hypothetical protein; integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; tmed10; tmed10.L; TMP21; Tmp-21-I; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; transmembrane protein; transmembrane protein tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10972
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P49755
Gene Symbols
TMED10
Immunogen
Recombinant protein corresponding to Human TMED10
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MFEVCFESKG TGRIPDQLVI LDMKHGVEAK NYEEIAKVEK LKPLEVELRR LEDLSESIVN DFAYMKKREE EMRDTNESTN TMP21 is a ubiquitously expressed protein that is involved in vesicular targeting and protein transport
- More recent experiments have shown that it is also a component in the presenilin complex and modulates the -gamma-secretase but not the epsilon-secretase cleavage activity of the amyloid precursor protein
- The presenilin complex is composed of the proteins APH1, nicastrin, and PEN2 in addition to presenilin-1
- Together, these proteins cleave the amyloid precursor protein at what is known as the -gamma- and epsilon-sites and can lead to the accumulation of the Abeta cleavage product that is associated with Alzheimer's disease
- Co-immunoprecipitation experiments using antibodies against these proteins also yielded TMP21 indicating that TMP21 may play a role in the regulation of this complex
- Suppression of TMP21 expression by siRNA in transfected cells caused increased -gamma-secretase activity but not epsilon-secretase activity, and increased Abeta production, demonstrating that TMP21 can modulate -gamma-secretase activity.
Compare Similar Items
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Antigen: TMP21
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMED10
Gene Alias: 1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; hypothetical protein; integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; tmed10; tmed10.L; TMP21; Tmp-21-I; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; transmembrane protein; transmembrane protein tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10972
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P49755
Gene Symbols: TMED10
Immunogen: Recombinant protein corresponding to Human TMED10
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TMP21
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMED10
Gene Alias:
1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; hypothetical protein; integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; tmed10; tmed10.L; TMP21; Tmp-21-I; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; transmembrane protein; transmembrane protein tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10972
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P49755
Gene Symbols:
TMED10
Immunogen:
Recombinant protein corresponding to Human TMED10
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: LAP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TOR1AIP1
Gene Alias: lamina-associated polypeptide 1B; Lamina-associated polypeptide 1C; Lamin-associated protein 1B; LAP1; LAP1B; Lap1c; Tor1aip1; torsin 1A interacting protein 1; torsin A interacting protein 1; torsin-1A-interacting protein 1
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26092
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.8 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q5JTV8
Gene Symbols: TOR1AIP1
Immunogen: Recombinant protein corresponding to Human TOR1AIP1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
LAP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TOR1AIP1
Gene Alias:
lamina-associated polypeptide 1B; Lamina-associated polypeptide 1C; Lamin-associated protein 1B; LAP1; LAP1B; Lap1c; Tor1aip1; torsin 1A interacting protein 1; torsin A interacting protein 1; torsin-1A-interacting protein 1
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26092
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.8 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q5JTV8
Gene Symbols:
TOR1AIP1
Immunogen:
Recombinant protein corresponding to Human TOR1AIP1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Calcineurin B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPP3R1
Gene Alias: ALNB1; calcineurin B, type I (19kDa); calcineurin subunit B type 1; CALNB1; CaNB1; Cna2; Cnb; Cnb1; MCIP1; PP2B beta 1; PPP3R1; protein phospatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I); protein phospatase 3, regulatory subunit B, alpha isoform,type 1; protein phosphatase 2B regulatory subunit 1; protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform; protein phosphatase 3 regulatory subunit B alpha; Protein phosphatase 3 regulatory subunit B alpha isoform 1; protein phosphatase 3 regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5534
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P63098
Gene Symbols: PPP3R1
Immunogen: Recombinant protein corresponding to Human PPP3R1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Calcineurin B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PPP3R1
Gene Alias:
ALNB1; calcineurin B, type I (19kDa); calcineurin subunit B type 1; CALNB1; CaNB1; Cna2; Cnb; Cnb1; MCIP1; PP2B beta 1; PPP3R1; protein phospatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I); protein phospatase 3, regulatory subunit B, alpha isoform,type 1; protein phosphatase 2B regulatory subunit 1; protein phosphatase 2B regulatory subunit B alpha; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, alpha isoform (calcineurin B, type I); protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform; protein phosphatase 3 regulatory subunit B alpha; Protein phosphatase 3 regulatory subunit B alpha isoform 1; protein phosphatase 3 regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha; protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I)
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5534
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P63098
Gene Symbols:
PPP3R1
Immunogen:
Recombinant protein corresponding to Human PPP3R1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NUP50
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NUP50
Gene Alias: 1700030K07Rik, 50 kDa nucleoporin, AI413123, CTA-268H5.7, DKFZP564A043, MGC39961, Npap60, NPAP60L, nuclear pore associated protein, nuclear pore associated protein 60 kDa, nuclear pore complex protein Nup50, nuclear pore complex protein Nup50, LOW QUALITY PROTEIN: nuclear pore complex protein Nup50, nuclear pore complex protein nup50-like protein, Nuclear pore-associated protein 60 kDa-like, nuclear pore-associated protein 60L, nucleoporin 50, nucleoporin 50 kDa, Nucleoporin 50 kDa-like protein, nucleoporin 50kD, nucleoporin 50kDa, nucleoporin Nup50, nucleoprotein 50, Nucleoprotein 50kD, Nup50, NUP50 protein, OTTHUMP00000199530, PRO1146, Rtp60, Unknown (protein for MGC:134469)
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10762
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q9UKX7
Gene Symbols: NUP50
Immunogen: Recombinant protein corresponding to Human NUP50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NUP50
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NUP50
Gene Alias:
1700030K07Rik, 50 kDa nucleoporin, AI413123, CTA-268H5.7, DKFZP564A043, MGC39961, Npap60, NPAP60L, nuclear pore associated protein, nuclear pore associated protein 60 kDa, nuclear pore complex protein Nup50, nuclear pore complex protein Nup50, LOW QUALITY PROTEIN: nuclear pore complex protein Nup50, nuclear pore complex protein nup50-like protein, Nuclear pore-associated protein 60 kDa-like, nuclear pore-associated protein 60L, nucleoporin 50, nucleoporin 50 kDa, Nucleoporin 50 kDa-like protein, nucleoporin 50kD, nucleoporin 50kDa, nucleoporin Nup50, nucleoprotein 50, Nucleoprotein 50kD, Nup50, NUP50 protein, OTTHUMP00000199530, PRO1146, Rtp60, Unknown (protein for MGC:134469)
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10762
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q9UKX7
Gene Symbols:
NUP50
Immunogen:
Recombinant protein corresponding to Human NUP50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG