PIPA584012
TMP21 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA584012-Each-of-1 | In Stock | ₹ 50,309.28 |
PIPA584012 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,309.28
GST (18%): ₹ 9,055.67
Total Price: ₹ 59,364.95
Antigen
TMP21
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TMED10
Gene Alias
1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; hypothetical protein; integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; tmed10; tmed10.L; TMP21; Tmp-21-I; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; transmembrane protein; transmembrane protein tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2
Host Species
Rabbit
Purification Method
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10972
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P49755
Gene Symbols
TMED10
Immunogen
Recombinant protein corresponding to Human TMED10
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: SFHLPINSRK CLREEIHKDL LVTGAYEISD QSGGAGGLRS HLKITDSAGH ILYSKEDATK GKFAFTTEDY D TMP21 is a ubiquitously expressed protein that is involved in vesicular targeting and protein transport
- More recent experiments have shown that it is also a component in the presenilin complex and modulates the -gamma-secretase but not the epsilon-secretase cleavage activity of the amyloid precursor protein
- The presenilin complex is composed of the proteins APH1, nicastrin, and PEN2 in addition to presenilin-1
- Together, these proteins cleave the amyloid precursor protein at what is known as the -gamma- and epsilon-sites and can lead to the accumulation of the Abeta cleavage product that is associated with Alzheimer's disease
- Co-immunoprecipitation experiments using antibodies against these proteins also yielded TMP21 indicating that TMP21 may play a role in the regulation of this complex
- Suppression of TMP21 expression by siRNA in transfected cells caused increased -gamma-secretase activity but not epsilon-secretase activity, and increased Abeta production, demonstrating that TMP21 can modulate -gamma-secretase activity.
Compare Similar Items
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Antigen: TMP21
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMED10
Gene Alias: 1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; hypothetical protein; integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; tmed10; tmed10.L; TMP21; Tmp-21-I; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; transmembrane protein; transmembrane protein tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10972
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P49755
Gene Symbols: TMED10
Immunogen: Recombinant protein corresponding to Human TMED10
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TMP21
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMED10
Gene Alias:
1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; hypothetical protein; integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; tmed10; tmed10.L; TMP21; Tmp-21-I; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; transmembrane protein; transmembrane protein tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10972
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P49755
Gene Symbols:
TMED10
Immunogen:
Recombinant protein corresponding to Human TMED10
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: LAP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TOR1AIP1
Gene Alias: lamina-associated polypeptide 1B, Lamina-associated polypeptide 1C, Lamin-associated protein 1B, LAP1, LAP1B, Lap1c, Tor1aip1, torsin 1A interacting protein 1, torsin A interacting protein 1, torsin-1A-interacting protein 1
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26092
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration: 0.3 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q5JTV8
Gene Symbols: TOR1AIP1
Immunogen: Recombinant protein corresponding to Human TOR1AIP1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
LAP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TOR1AIP1
Gene Alias:
lamina-associated polypeptide 1B, Lamina-associated polypeptide 1C, Lamin-associated protein 1B, LAP1, LAP1B, Lap1c, Tor1aip1, torsin 1A interacting protein 1, torsin A interacting protein 1, torsin-1A-interacting protein 1
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26092
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration:
0.3 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q5JTV8
Gene Symbols:
TOR1AIP1
Immunogen:
Recombinant protein corresponding to Human TOR1AIP1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ZBTB10
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZBTB10
Gene Alias: 4832414A18; AU021107; RINZF; RINZFC; ZBTB10; zinc finger and BTB domain containing 10; zinc finger and BTB domain-containing protein 10; Zinc finger protein RIN ZF; zinc finger protein RINZF
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 65986
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.4 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q96DT7
Gene Symbols: ZBTB10
Immunogen: Recombinant protein corresponding to Human ZBTB10
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ZBTB10
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZBTB10
Gene Alias:
4832414A18; AU021107; RINZF; RINZFC; ZBTB10; zinc finger and BTB domain containing 10; zinc finger and BTB domain-containing protein 10; Zinc finger protein RIN ZF; zinc finger protein RINZF
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
65986
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.4 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q96DT7
Gene Symbols:
ZBTB10
Immunogen:
Recombinant protein corresponding to Human ZBTB10
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: C10orf46
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CACUL1
Gene Alias: 2700078E11Rik; 2810417M16Rik; 9830127L17Rik; AI450346; C10orf46; CAC1; CACUL1; CDK2 associated cullin domain 1; CDK2 associated, cullin domain 1; CDK2-associated and cullin domain-containing protein 1; CDK2-associated, cullin domain 1; Cdk-associated cullin1; cullin; D130033C15Rik; RGD1308127
Host Species: Rabbit
Purification Method: Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 143384
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.2 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q86Y37
Gene Symbols: CACUL1
Immunogen: Recombinant protein corresponding to Human CACUL1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
C10orf46
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CACUL1
Gene Alias:
2700078E11Rik; 2810417M16Rik; 9830127L17Rik; AI450346; C10orf46; CAC1; CACUL1; CDK2 associated cullin domain 1; CDK2 associated, cullin domain 1; CDK2-associated and cullin domain-containing protein 1; CDK2-associated, cullin domain 1; Cdk-associated cullin1; cullin; D130033C15Rik; RGD1308127
Host Species:
Rabbit
Purification Method:
Anitgen affinity chromatography, Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
143384
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.2 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q86Y37
Gene Symbols:
CACUL1
Immunogen:
Recombinant protein corresponding to Human CACUL1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG