PIPA585185

c-Myc Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA585185-Each-of-1 In Stock ₹ 44,533.98

PIPA585185 - Each of 1

₹ 44,533.98

In Stock

Quantity

1

Base Price: ₹ 44,533.98

GST (18%): ₹ 8,016.116

Total Price: ₹ 52,550.096

Antigen

c-Myc

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MYC

Gene Alias

AU016757, Avian myelocytomatosis viral (v-myc) oncogene homolog, avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, class E basic helix-loop-helix protein 39, cmyc, c-Myc, c-myc epitope tag, c-myc proto-oncogene, mMyc, MRTL, Myc, Myc protein, Myc proto-oncogene protein, MYC proto-oncogene, bHLH transcription factor, Myc2, MYCC, myc-related translation/localization regulatory factor, myelocytomatosis oncogene, myelocytomatosis viral oncogene homolog, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene-like protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17869, 4609

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

0.29 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.

P01106, P01108

Gene Symbols

MYC

Immunogen

Recombinant protein encompassing a sequence within the center region of human c-Myc.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Keep as concentrated solution
  • Predicted reactivity: Mouse (89%), Rat (86%), Dog (93%), Cat (91%), Pig (94%), Rabbit (93%), Sheep (92%), Rhesus Monkey (98%), Chimpanzee (99%), Bovine (92%)
  • Positive Control: 293T, NIH-3T3, Raw264.7, HeLa, HeLa nuclear extract
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • The c-Myc protein is a 62 kDa transcription factor that is encoded by the c-Myc gene on human chromosome 8q24
  • c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression
  • The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation
  • Studies have shown that c-Myc is essential for vasculogenesis and angiogenesis in tumor development, which distributes blood throughout the cells
  • The c-myc oncogene (p62 c-myc) is involved in the control of normal cellular proliferation and differentiation, and the deregulated expression of c-Myc induces apoptosis in different cell types
  • Antibodies against c-myc epitopes recognize overexpressed proteins containing Myc epitope tag fused to either amino- or carboxy-termini of targeted proteins
  • c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease
  • Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas
  • Translocation of the c-myc locus on chromosome 8 to the immunoglobulin loci on chromosome 14 (heavy chain); 2 (delta light chain); or 22 (light chain) is described in Burkitts lymphoma and other B-cell lymphoproliferative conditions
  • An aberrant expression of the c-myc gene occurs in tumors of different origins such as colorectal, gastric, gallbladder, hepatic, mammary, ovarian, endometrial, head and neck, pulmonary, prostatic, thyroidal, oral, ocular, nasopharyngeal, endocrine, as well as hematopoietic neoplasms.

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Img

Thermo Scientific

PIPA585185

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Antigen:
c-Myc

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYC

Gene Alias:
AU016757, Avian myelocytomatosis viral (v-myc) oncogene homolog, avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, class E basic helix-loop-helix protein 39, cmyc, c-Myc, c-myc epitope tag, c-myc proto-oncogene, mMyc, MRTL, Myc, Myc protein, Myc proto-oncogene protein, MYC proto-oncogene, bHLH transcription factor, Myc2, MYCC, myc-related translation/localization regulatory factor, myelocytomatosis oncogene, myelocytomatosis viral oncogene homolog, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene-like protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17869, 4609

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.29 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
P01106, P01108

Gene Symbols:
MYC

Immunogen:
Recombinant protein encompassing a sequence within the center region of human c-Myc.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585186

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Antigen:
tPA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLAT

Gene Alias:
3.4.21.68; Alteplase; AU020998; AW212668; D8Ertd2e; PATISS; plasminogen activator, tissue; plasminogen activator, tissue type; plasminogen/activator kringle; PLAT; Reteplase; serine protease; t plasminogen activator; tissue plasminogen activator; tissue-type plasminogen activator; Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B; TPA; t-PA; t-plasminogen activator

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18791, 25692, 5327

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.15 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P00750, P11214, P19637

Gene Symbols:
PLAT

Immunogen:
Recombinant protein encompassing a sequence within the center region of human tPA.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585187

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Antigen:
Desmin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DES

Gene Alias:
CMD1I; CSM1; CSM2; DES; Desmin; desmin-like protein; FLJ12025; FLJ39719; FLJ41013; FLJ41793; I79_018932; intermediate filament protein; LGMD2R; MFM1; muscle-specific intermediate filament desmin; muscle-specific intermediate filament protein; mutant desmin p.K241E; SCPNK; similar to desmin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13346, 1674, 395906, 64362

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.06 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
P02542, P17661, P31001, P48675

Gene Symbols:
DES

Immunogen:
Recombinant protein encompassing a sequence within the center region of human Desmin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Chicken, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585190

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Antigen:
HIF-2 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPAS1

Gene Alias:
basic-helix-loop-helix-PAS protein MOP2, bHLHe73, Class E basic helix-loop-helix protein 73, ECYT4, endothelial PAS domain protein 1, endothelial PAS domain protein 1b, endothelial PAS domain-containing protein 1, endothelial PAS domain-containing protein 1b, EPAS, Epas1, EPAS-1, epas1b, Hif like protein, HIF1 alpha-like factor, HIF-1-alpha-like factor, HIF-1alpha-like factor, HIF1alpha-like factor, HIF2 alpha, HIF-2 alpha, HIF2A, hif-2a, hif-2ab, HIF-2alpha, HIF-2-alpha, HIF2-alpha, HIF-related factor, HLF, HLF (HIF1alpha-like factor), HRF, hypoxia inducible factor 2 alpha, hypoxia inducible factor 2, alpha subunit, hypoxia inducible factor 2a, hypoxia inducible transcription factor 2alpha, hypoxia-inducible factor 2 alpha, hypoxia-inducible factor 2-alpha, Member of PAS protein 2, mHLF, MOP2, PAS domain-containing protein 2, PASD2, wu:fq36f01

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2034, 555192

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
Q99814

Gene Symbols:
EPAS1, epas1b

Immunogen:
Recombinant protein encompassing a sequence within the center region of human HIF2 alpha.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Zebrafish

Product Type:
Antibody

Isotype:
IgG