PIPA585209

HLA-DRB3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585209-Each-of-1 In Stock ₹ 44,705.10

PIPA585209 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

HLA-DRB3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HLA-DRB3

Gene Alias

DR7, DRB1, DRw10, HLA class II histocompatibility antigen, DR beta 3 chain, HLA class II histocompatibility antigen, DRB1-7 beta chain, HLA DR3B, HLA-DR1B, HLA-DR3B, HLA-DRB, HLA-DRB3, human leucocyte antigen DRB3, major histocompatibility complex, class II, DR beta 3, MGC117330, MHC Class II antigen, MHC class II antigen DR beta 3 chain, MHC class II antigen DRB3, MHC class II HLA-DR beta 3 chain, SS1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3125

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunofluorescence

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.

P79483

Gene Symbols

HLA-DRB3

Immunogen

Recombinant protein encompassing a sequence within the center region of human HLA-DRB3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Keep as concentrated solution
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Major histocompatibility complex (MHC) class II molecules destined for presentation to CD4+ helper T cells is determined by two key events
  • These events include the dissociation of class II-associated invariant chain peptides (CLIP) from an antigen binding groove in mhc ii-a/b dimers through the activity of MHC molecules HLA-DM and -DO, and subsequent peptide antigen binding
  • Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM, -DO molecules regulate the dissociation of CLIP and the subsequent binding of exogenous peptides to HLA class II molecules (HLA-DR, -DQ and -DP) by sustaining a conformation that favors peptide exchange
  • RFLP analysis of HLA-DM genes from rheumatoid arthritis (RA) patients suggests that certain polymorphisms are genetic factors for RA susceptibility
  • HLA-B belongs to the HLA class I heavy chain paralogs
  • Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen
  • HLA-B and -C can form heterodimers consisting of a membrane anchored heavy chain and a light chain ( beta-2-Microglobulin)
  • Polymorphisms yield hundreds of HLA-B and -C alleles
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA585209

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Antigen:
HLA-DRB3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLA-DRB3

Gene Alias:
DR7, DRB1, DRw10, HLA class II histocompatibility antigen, DR beta 3 chain, HLA class II histocompatibility antigen, DRB1-7 beta chain, HLA DR3B, HLA-DR1B, HLA-DR3B, HLA-DRB, HLA-DRB3, human leucocyte antigen DRB3, major histocompatibility complex, class II, DR beta 3, MGC117330, MHC Class II antigen, MHC class II antigen DR beta 3 chain, MHC class II antigen DRB3, MHC class II HLA-DR beta 3 chain, SS1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3125

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
P79483

Gene Symbols:
HLA-DRB3

Immunogen:
Recombinant protein encompassing a sequence within the center region of human HLA-DRB3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA585210

--


Antigen:
LOXL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LOXL2

Gene Alias:
1110004B06Rik, 4930526G11Rik, 9430067E15Rik, LOR2, Loxl2, Lysyl oxidase homolog 2, lysyl oxidase homolog 2, LOW QUALITY PROTEIN: lysyl oxidase homolog 2, lysyl oxidase like 2, lysyl oxidase related 2, lysyl oxidase-like 2, lysyl oxidase-like 2 delta e13, lysyl oxidase-like 2 protein, lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, lysyl oxidase-related protein WS9-14, WS9-14

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4017, 94352

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot

Concentration:
0.7 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
P58022, Q9Y4K0

Gene Symbols:
LOXL2

Immunogen:
Recombinant protein encompassing a sequence within the center region of human LOXL2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA585211

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Antigen:
ADAMTS4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADAMTS4

Gene Alias:
3830423K05, a disintegrin and metallopeptidase with thrombospondin motifs 4, a disintegrin and metalloproteinase, A disintegrin and metalloproteinase with thrombospondin motifs 4, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4, ADAM, ADAM metallopeptidase with thrombospondin type 1 motif 4, ADAM metallopeptidase with thrombospondin type 1 motif, 4, ADAMs, ADAM-TS 4, ADAMTS family member, ADAMTS-2, Adamts4, ADAM-TS4, ADAMTS-4, ADMP-1, Aggrecanase, Aggrecanase 1, aggrecanase-1, disintegrin and metalloproteinase with thrombospondin motifs 2, KIAA0688, metalloendopeptidases, metalloproteinase, mKIAA0688, UNQ769/PRO1563

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
240913, 9507

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.33 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
O75173, Q8BNJ2

Gene Symbols:
ADAMTS4

Immunogen:
Recombinant protein encompassing a sequence within the center region of human ADAMTS4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA585213

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Antigen:
PLCL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLCL1

Gene Alias:
130kDa-Ins(1,4,5)P3 binding protein; C230017K02Rik; inactive phospholipase C-like protein 1; p130; phospholipase C like 1; phospholipase C related, but catalytically inactive protein; phospholipase C, epsilon; phospholipase C, eta 2 pseudogene; phospholipase C-deleted in lung carcinoma; phospholipase C-like 1; phospholipase C-related but catalytically inactive protein; PLCE; PLCL; PLC-L; PLCL1; PLC-L1; PLDL1; PPP1R127; PRIP; PRIP1; PRIP-1; protein phosphatase 1, regulatory subunit 127

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
227120, 5334

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.92 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q15111, Q3USB7

Gene Symbols:
PLCL1

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human PLCL1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG