PIPA587621
HLA-DRB4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587621-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA587621 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
HLA-DRB4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HLA-DRB4
Gene Alias
DR4, DR-4, DRB1 transplantation antigen, DRB4, HLA class II histocompatibility antigen, DR beta 4 chain, HLA-DR4B, HLA-DRB4, human leucocyte antigen DRB4, leukocyte antigen, major histocompatibility complex, class II, DR beta 4, MHC class II antigen DRB4, MHC class II antigen HLA-DR-beta, MHC class2 antigen, MHC HLA DR-beta chain
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3126
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.49 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P13762
Gene Symbols
HLA-DRB4
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 30-227 of human HLA-DRB4 (NP_0688184)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: GDTQPRFLEQ AKCECHFLNG TERVWNLIRY IYNQEEYARY NSDLGEYQAV TELGRPDAEY WNSQKDLLER RRAEVDTYCR YNYGVVESFT VQRRVQPKVT VYPSKTQPLQ HHNLLVCSVN GFYPGSIEVR WFRNGQEEKA GVVSTGLIQN GDWTFQTLVM LETVPRSGEV YTCQVEHPSM MSPLTVQWSA RSESAQSK; Positive Samples: Raji, Mouse brain; Cellular Location: Cell membrane, Endoplasmic reticulum membrane, Endosome membrane, Golgi apparatus, Late endosome membrane, Lysosome membrane, Single-pass type I membrane protein, trans-Golgi network membrane HLA-DRB4 belongs to the HLA class II beta chain paralogues
- This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane
- It plays a central role in the immune system by presenting peptides derived from extracellular proteins
- Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages)
- The beta chain is approximately 26-28 kDa and its gene contains 6 exons
- Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail
- Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities
- Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
- DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5
- The presence of DRB4 is linked with allelic variants of DRB1, otherwise it is omitted
- There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9
- HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
Compare Similar Items
Show Difference
Antigen: HLA-DRB4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HLA-DRB4
Gene Alias: DR4, DR-4, DRB1 transplantation antigen, DRB4, HLA class II histocompatibility antigen, DR beta 4 chain, HLA-DR4B, HLA-DRB4, human leucocyte antigen DRB4, leukocyte antigen, major histocompatibility complex, class II, DR beta 4, MHC class II antigen DRB4, MHC class II antigen HLA-DR-beta, MHC class2 antigen, MHC HLA DR-beta chain
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3126
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.49 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P13762
Gene Symbols: HLA-DRB4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-227 of human HLA-DRB4 (NP_0688184)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
HLA-DRB4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HLA-DRB4
Gene Alias:
DR4, DR-4, DRB1 transplantation antigen, DRB4, HLA class II histocompatibility antigen, DR beta 4 chain, HLA-DR4B, HLA-DRB4, human leucocyte antigen DRB4, leukocyte antigen, major histocompatibility complex, class II, DR beta 4, MHC class II antigen DRB4, MHC class II antigen HLA-DR-beta, MHC class2 antigen, MHC HLA DR-beta chain
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3126
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.49 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P13762
Gene Symbols:
HLA-DRB4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-227 of human HLA-DRB4 (NP_0688184)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: NMDAR2D
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GRIN2D
Gene Alias: EB11, estrogen receptor binding CpG island, GluN2D, glur epsilon 4, GluRepsilon4, glutamate [NMDA] receptor subunit epsilon-4, glutamate ionotropic receptor NMDA type subunit 2D, glutamate receptor, glutamate receptor ionotropic, NMDA 2D, glutamate receptor, ionotropic, NMDA2D, glutamate receptor, ionotropic, NMDA2D (epsilon 4), glutamate receptor, ionotropic, N-methyl D-aspartate 2D, GRIN2D, ionotropic NMDA glutamate receptor epsilon 4 subunit type 2, NMDAR2D, N-methyl D-aspartate receptor subtype 2D, N-methyl-d-aspartate receptor subunit 2D, NR2D
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14814, 2906
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 3.07 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O15399, Q03391
Gene Symbols: GRIN2D
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 330-480 of human GRIN2D (NP_0008272)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NMDAR2D
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GRIN2D
Gene Alias:
EB11, estrogen receptor binding CpG island, GluN2D, glur epsilon 4, GluRepsilon4, glutamate [NMDA] receptor subunit epsilon-4, glutamate ionotropic receptor NMDA type subunit 2D, glutamate receptor, glutamate receptor ionotropic, NMDA 2D, glutamate receptor, ionotropic, NMDA2D, glutamate receptor, ionotropic, NMDA2D (epsilon 4), glutamate receptor, ionotropic, N-methyl D-aspartate 2D, GRIN2D, ionotropic NMDA glutamate receptor epsilon 4 subunit type 2, NMDAR2D, N-methyl D-aspartate receptor subtype 2D, N-methyl-d-aspartate receptor subunit 2D, NR2D
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14814, 2906
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
3.07 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O15399, Q03391
Gene Symbols:
GRIN2D
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 330-480 of human GRIN2D (NP_0008272)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MEP1B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mep1b
Gene Alias: EC 3.4.24.63, Endopeptidase-2, MEP1B, Mep-1b, meprin 1 beta, meprin A, meprin A subunit beta, meprin A, beta, meprin B, meprin beta, N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta subunit, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta, PABA peptide hydrolase, PPH beta
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17288
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.63 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q61847
Gene Symbols: Mep1b
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 480-652 of human MEP1B (NP_0059162)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MEP1B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mep1b
Gene Alias:
EC 3.4.24.63, Endopeptidase-2, MEP1B, Mep-1b, meprin 1 beta, meprin A, meprin A subunit beta, meprin A, beta, meprin B, meprin beta, N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta subunit, N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta, PABA peptide hydrolase, PPH beta
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17288
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.63 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q61847
Gene Symbols:
Mep1b
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 480-652 of human MEP1B (NP_0059162)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: IL1RL2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL1RL2
Gene Alias: AI481289, AW551444, IL-1 receptor-related protein 2, IL1RL2, IL1RRP2, IL-1Rrp2, IL1R-rp2, IL-36 receptor, IL-36R, interleukin 1 receptor like 2, interleukin 1 receptor-like 2, interleukin-1 receptor related protein 2, interleukin-1 receptor-like 2, Interleukin-1 receptor-related protein 2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 107527, 8808
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.28 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q9ERS7, Q9HB29
Gene Symbols: IL1RL2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-116 of human IL36R (NP_0038452)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
IL1RL2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL1RL2
Gene Alias:
AI481289, AW551444, IL-1 receptor-related protein 2, IL1RL2, IL1RRP2, IL-1Rrp2, IL1R-rp2, IL-36 receptor, IL-36R, interleukin 1 receptor like 2, interleukin 1 receptor-like 2, interleukin-1 receptor related protein 2, interleukin-1 receptor-like 2, Interleukin-1 receptor-related protein 2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
107527, 8808
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.28 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q9ERS7, Q9HB29
Gene Symbols:
IL1RL2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-116 of human IL36R (NP_0038452)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG