PIPA585345

CDK4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585345-Each-of-1 In Stock ₹ 44,705.10

PIPA585345 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CDK4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cdk4

Gene Alias

Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1019

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.82 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P11802

Gene Symbols

Cdk4

Immunogen

Recombinant protein encompassing a sequence within the center region of human CDK4.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Keep as concentrated solution
  • Predicted reactivity: Mouse (95%), Rat (95%), Pig (98%), Sheep (96%), Rhesus Monkey (100%), Bovine (96%)
  • Positive Control: 293T
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • CDK4/cyclin D3 serine/threonine kinase is dimeric protein complex
  • CDK4 is a member of the cyclin-dependent protein kinase family and is involved in the control of cell proliferation during the G1 phase of cell cycle
  • CDK4 forms a complex with the D-type cyclins and is inhibited by p16 (cyclin-dependent kinase inhibitor-2)
  • CDK4 can mediate phosphorylation of the C-terminal region of Rb protein leading to an active transcriptional repression of E2F complex
  • CDC37 and HSP90 can preferentially associate with the fraction of CDK4 not bound to D-type cyclins
  • SMAD3 is a major physiologic substrate of the G1 cyclin-dependent kinases CDK4 and CDK2
  • Although CDK6 and CDK4 can both phosphorylate multiple residues in the Rb protein, they do so with different residue selectivity in vitro; CDK6 phosphorylates Thr821 while CDK4 phosphorylates Thr826 on Rb protein.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA585345

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Antigen:
CDK4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cdk4

Gene Alias:
Cdk4; Cell division protein kinase 4; CMM3; Crk3; cyclin dependent kinase 4; cyclin-dependent kinase 4; MGC14458; p34<PSK-J3>/cdk4; PSK-J3; serine/threonine kinase; Unknown (protein for MGC:133903)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1019

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.82 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P11802

Gene Symbols:
Cdk4

Immunogen:
Recombinant protein encompassing a sequence within the center region of human CDK4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585346

--


Antigen:
CREB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CREB1

Gene Alias:
2310001E10Rik, 3526402H21Rik, active transcription factor CREB, AV083133, cAMP response element binding protein 1, cAMP responsive element binding protein 1, cAMP-response element-binding protein-1, cAMP-responsive element-binding protein 1, CREB, CREB1, Creb-1, cyclic adenosine 3',5'-monophosphate response element-binding protein CREB, cyclic AMP-responsive element-binding protein 1, htCREB, MGC9284, OTTHUMP00000206661, OTTHUMP00000206662, OTTHUMP00000206667, transactivator protein, Y protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12912, 1385, 81646

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.28 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
P15337, P16220, Q01147

Gene Symbols:
CREB1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human CREB.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585347

--


Antigen:
ERCC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERCC1

Gene Alias:
COFS4, DNA excision repair protein ERCC-1, ERCC excision repair 1, endonuclease non-catalytic subunit, Ercc1, Ercc-1, excision repair cross-complementation group 1, excision repair cross-complementing 1, excision repair cross-complementing rodent repair deficiency, complementation group 1, excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence), hypothetical protein LOC405807, RAD10, UV20, zgc:77511

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2067

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.86 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
P07992

Gene Symbols:
ERCC1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human ERCC1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585348

--


Antigen:
ARF6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARF6

Gene Alias:
ADP ribosylation factor 6; ADP-ribosylation factor 6; AI788669; ARF6; AW496366; DKFZp564M0264

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11845, 382, 79121

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.89 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P62330, P62331, P62332

Gene Symbols:
ARF6

Immunogen:
Recombinant protein encompassing a sequence within the center region of human ARF6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG