PIPA585242

SPHK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA585242-Each-of-1 In Stock ₹ 44,705.10

PIPA585242 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SPHK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SPHK1

Gene Alias

1110006G24Rik, Acetyltransferase SPHK1, RP23-193A16.4, SK 1, Sk1, SKase, Sphingosine kinase 1, SPHK, SPHK1, SPK, SPK 1, Spk1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8877

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot, Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.

Q9NYA1

Gene Symbols

SPHK1

Immunogen

Recombinant protein encompassing a sequence within the center region of human SPHK1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Keep as concentrated solution
  • Positive Control: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P)
  • S1P signals through G-protein coupled receptors and controls diverse cellular processes
  • Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer
  • SPHK1 catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions
  • Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine
  • S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis
  • The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).

Compare Similar Items

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Img

Thermo Scientific

PIPA585242

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Antigen:
SPHK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPHK1

Gene Alias:
1110006G24Rik, Acetyltransferase SPHK1, RP23-193A16.4, SK 1, Sk1, SKase, Sphingosine kinase 1, SPHK, SPHK1, SPK, SPK 1, Spk1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8877

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot, Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
Q9NYA1

Gene Symbols:
SPHK1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human SPHK1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585243

--


Antigen:
PINK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PINK1

Gene Alias:
1190006F07Rik, AU042772, AW557854, BRPK, FLJ27236, mFLJ00387, PARK6, PINK 1, Pink1, PINK-1, protein kinase BRPK, PTEN induced putative kinase 1, PTEN-induced putative kinase protein 1, Serine/threonine-protein kinase PINK1, mitochondrial

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
65018, 68943

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot, Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
Q99MQ3, Q9BXM7

Gene Symbols:
PINK1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human PINK1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA585246

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Antigen:
IKK beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ikbkb

Gene Alias:
AI132552, AIM-1, FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, Ikbkb, IKK[b], IKK2, IKK-2, IKKB, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, nuclear factor NF-kappa-B inhibitor kinase beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3551

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Western Blot

Concentration:
0.96 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
O14920

Gene Symbols:
Ikbkb

Immunogen:
Recombinant protein encompassing a sequence within the center region of human IKK beta.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585247

--


Antigen:
TRIM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Trim2

Gene Alias:
CMT2R, E3 ubiquitin-protein ligase TRIM2, KIAA0517, mKIAA0517, narf, Neural activity-related RING finger protein, RING finger protein 86, RING-type E3 ubiquitin transferase TRIM2, RNF86, TRIM2, tripartite motif containing 2, tripartite motif protein 2, tripartite motif protein TRIM2, tripartite motif-containing 2, tripartite motif-containing protein 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23321

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.28 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
Q9C040

Gene Symbols:
Trim2

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TRIM2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG