PIPA585552

PROX1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585552-Each-of-1 In Stock ₹ 44,619.54

PIPA585552 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

PROX1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Prox1

Gene Alias

A230003G05Rik, homeobox prospero-like protein PROX1, prospero homeobox 1, prospero homeobox protein 1, prospero-related homeobox 1, Prox 1, PROX1, PROX-1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19130, 305066, 5629

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.

P48437, Q92786

Gene Symbols

Prox1

Immunogen

Recombinant protein encompassing a sequence within the center region of human PROX1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Keep as concentrated solution
  • Predicted reactivity: Mouse (97%), Rat (97%), Pig (97%), Chicken (89%), Rhesus Monkey (100%), Bovine (97%)
  • Positive Control: HepG2 nuclear extract, mouse hippocampus, mouse eye, fetal mouse forebrain
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • The expression pattern of the Prox1 homeo box gene suggests that it has a role in a variety of embryonic tissues, including lens
  • Analysis of mRNA reveals that Prox mRNA is present in many different human tissues and that lens demonstrated the highest level
  • Homozygous Prox1-null mice die at midgestation from multiple developmental defects, and a targeted effect on lens development has been reported
  • Prox1 inactivation caused abnormal cellular proliferation, downregulated expression of the cell cycle inhibitors Cdkn1b and Cdkn1c, misexpression of E-cadherin, and excessive apoptosis
  • Consequently, mutant lens cells failed to polarize and elongate properly, resulting in a hollow lens
  • The Prox1 gene is expressed in a subpopulation of endothelial cells that by budding and sprouting give rise to the lymphatic system
  • Prox1 appears to be a specific and required regulator of the development of the lymphatic system
  • Prox1 also has been document to be required for hepatocyte migration in the mouse
  • Loss of Prox1 results in a smaller liver with a reduced population of clustered hepatocytes
  • The homeodomain protein Prox1 regulates the egress of progenitor cells from the cell cycle in the embryonic mouse retina
  • Cells lacking Prox1 are less likely to stop dividing, and ectopic expression of Prox1 forces progenitor cells to exit the cell cycle
  • Prox1 acts as a key participant in progenitor-cell proliferation and cell-fate determination in the vertebrate retina.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA585552

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Antigen:
PROX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Prox1

Gene Alias:
A230003G05Rik, homeobox prospero-like protein PROX1, prospero homeobox 1, prospero homeobox protein 1, prospero-related homeobox 1, Prox 1, PROX1, PROX-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19130, 305066, 5629

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
P48437, Q92786

Gene Symbols:
Prox1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human PROX1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585553

--


Antigen:
SIRT2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIRT2

Gene Alias:
5730427M03Rik, 5E5 antigen, mSIR2L2, NAD-dependent deacetylase sirtuin-2, NAD-dependent protein deacetylase sirtuin-2, Regulatory protein SIR2 homolog 2, silent information regulator 2, silent mating type information regulation 2, (S.cerevisiae, homolog)-like, sirtuin 2, SIR2, SIR2L, SIR2L2, SIR2-like protein 2, sir2-related protein type 2, Sirt2, sirtuin 2, sirtuin type 2, sirtuin-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22933, 361532

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
Q5RJQ4, Q8IXJ6

Gene Symbols:
SIRT2

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human SIRT2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585554

--


Antigen:
SIN3A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIN3A

Gene Alias:
AW553200, Histone deacetylase complex subunit Sin3a, Kiaa4126, Mammalian Sin3A, mKIAA4126, mSin3A, Paired amphipathic helix protein Sin3a, SIN, Sin3, SIN3 homolog A, transcription regulator, SIN3 transcription regulator family member A, SIN3 transcription regulator homolog A, SIN3A, transcriptional corepressor Sin3a, transcriptional co-repressor Sin3A, transcriptional regulator, SIN3 yeast homolog A, transcriptional regulator, SIN3A, transcriptional regulator, SIN3A (yeast)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20466, 25942, 363067

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1.38 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
Q60520, Q96ST3

Gene Symbols:
SIN3A

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human SIN3A.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585559

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Antigen:
NFATC4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nfatc4

Gene Alias:
3110041H08Rik; AW107667; AW546455; Nfat3; NF-AT3; Nfatc4; NF-ATc4; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4; nuclear factor of activated T-cells 4; nuclear factor of activated T-cells, cytoplasmic 4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; T-cell transcription factor NFAT3; transcription complex subunit NF-ATc4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4776

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q14934

Gene Symbols:
Nfatc4

Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human NFATC4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG