PIPA585366

IL-1 alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585366-Each-of-1 In Stock ₹ 45,560.70

PIPA585366 - Each of 1

₹ 45,560.70

In Stock

Quantity

1

Base Price: ₹ 45,560.70

GST (18%): ₹ 8,200.926

Total Price: ₹ 53,761.626

Antigen

IL-1 alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Il1a

Gene Alias

CTLA8, hematopoietin-1, IL 1 a, IL 1a, IL1, IL-1 alpha, IL17, IL1A, Il-1a, IL-1alpha, IL1-ALPHA, IL1F1, IL1a, ILN, Interleukin, interleukin 1 alpha, interleukin 1, alpha, interleukin 17, interleukin 1a, interleukin 1-alpha, interleukin 1-alpha (AA 1 - 152), Interleukin1 alpha, interleukin-1 alpha, interleukin-1 alpha precursor, Interleukin-17A, preinterleukin 1 alpha, pre-interleukin-1 alpha, pro-interleukin-1-alpha, RP23-160G19.8

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3552

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot

Concentration

1.09 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.

P01583

Gene Symbols

Il1a

Immunogen

Recombinant protein encompassing a sequence within the center region of human IL1 alpha.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Keep as concentrated solution
  • Predicted reactivity: Rhesus Monkey (89%)
  • Positive Control: HepG2
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • IL-1 alpha (Interleukin-1 alpha) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells
  • IL-1 alpha is coded by the IL1A gene and signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 beta
  • IL1A is located on the q arm on chromosome 2 at position 13
  • IL-1 alpha plays an important role in innate host defense by triggering the production of other proinflammatory cytokines in target cells and initiating acute-phase responses
  • IL-1 alpha activity can be moderated by IL-1 Receptor Antagonist (IL-1RA), a protein produced by many cell types that blocks receptor binding through competitive inhibition
  • IL-1 alpha is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis
  • Further, IL-1 alpha is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury and induces apoptosis
  • The IL1A gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2
  • IL1 alpha regulates the activities of NF-kappaB and mitogen-activated protein kinases
  • IL-1 alpha can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO)
  • High levels of IL-1 alpha are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA585366

--


Antigen:
IL-1 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il1a

Gene Alias:
CTLA8, hematopoietin-1, IL 1 a, IL 1a, IL1, IL-1 alpha, IL17, IL1A, Il-1a, IL-1alpha, IL1-ALPHA, IL1F1, IL1a, ILN, Interleukin, interleukin 1 alpha, interleukin 1, alpha, interleukin 17, interleukin 1a, interleukin 1-alpha, interleukin 1-alpha (AA 1 - 152), Interleukin1 alpha, interleukin-1 alpha, interleukin-1 alpha precursor, Interleukin-17A, preinterleukin 1 alpha, pre-interleukin-1 alpha, pro-interleukin-1-alpha, RP23-160G19.8

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3552

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot

Concentration:
1.09 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
P01583

Gene Symbols:
Il1a

Immunogen:
Recombinant protein encompassing a sequence within the center region of human IL1 alpha.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585368

--


Antigen:
alpha Actinin 4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Actn4

Gene Alias:
actinin alpha 4, ACTININ-4, actinin-Alpha-4, Actn4, alpha actinin 4, alpha-actinin-4, C77391, F-actin cross-linking protein, focal segmental glomerulosclerosis 1, FSGS, FSGS1, non-muscle alpha-actinin 4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
60595, 63836, 81

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
O43707, P57780, Q9QXQ0

Gene Symbols:
Actn4

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human alpha Actinin 4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585369

--


Antigen:
BMPR1A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BMPR1A

Gene Alias:
10q23del, 1110037I22Rik, activin A receptor, type II-like kinase 3, activin receptor-like kinase 3, ACVRLK3, ALK3, ALK-3, AU045487, BMP type-1A receptor, BMP-2/BMP-4 receptor, Bmpr, Bmpr1a, BMPR-1A, BMPRIA, BMPR-IA, Bone morphogenetic protein 4 receptor, bone morphogenetic protein receptor type 1A, bone morphogenetic protein receptor type IA, bone morphogenetic protein receptor type-1A, bone morphogenetic protein receptor, type 1A, bone morphogenetic protein receptor, type IA, CD292, Serine/threonine-protein kinase receptor R5, SKR5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
657

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
P36894

Gene Symbols:
BMPR1A

Immunogen:
Recombinant protein encompassing a sequence within the center region of human BMPR1A.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA585370

--


Antigen:
CEA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ceacam5

Gene Alias:
1600029H12Rik; Carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; carcinoembryonic antigen-related cell adhesion molecule 5; CD66e; CEA; CEACAM5; Meconium antigen 100; OTTHUMP00000199033; pregnancy-specific glycoprotein 30; Psg30; sCD66e; soluble CD66e

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1048

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.71 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P06731

Gene Symbols:
Ceacam5

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human CD66e.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG