PIPA588078
IL-1 beta Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588078-Each-of-1 | In Stock | ₹ 44,619.54 |
PIPA588078 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,619.54
GST (18%): ₹ 8,031.517
Total Price: ₹ 52,651.057
Antigen
IL-1 beta
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IL1B
Gene Alias
catabolin, cytokine, Hematopoietin 1 (H1), IFN beta inducing factor, il 1b, IL 1β, IL-1, IL1 B, IL-1 beta, IL-1 precursor, IL1B, IL-1B, IL1B1, IL1beta, IL-1beta, IL1-BETA, IL1F2, IL1β, ILN, Interleukin, interleukin 1 beta, Interleukin 1 beta precursor, interleukin 1, beta, interleukin 1, beta 1, interleukin 1-beta, interleukin*1*beta, Interleukin1 beta, interleukin-1 beta, interleukin-1 beta precursor, interleukin-1 beta precursor (AA -113 to 153), interleukin-1 beta proprotein, interleukin-1b, interleukin-1beta, interleukin-beta, LAF, lymphocyte proliferation-potentiating factor, Osteoclast activating factor (OAF), preinterleukin 1 beta, Pro interleukin 1 beta, prointerleukin-1 beta, pro-interleukin-1-beta
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16176, 24494, 3553
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.97 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P01584, P10749, Q63264
Gene Symbols
IL1B
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-269 of human IL1beta (NP_0005671)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MAEVPELASE MMAYYSGNED DLFFEADGPK QMKCSFQDLD LCPLDGGIQL RISDHHYSKG FRQAASVVVA MDKLRKMLVP CPQTFQENDL STFFPFIFEE EPIFFDTWDN EAYVHDAPVR SLNCTLRDSQ QKSLVMSGPY ELKALHLQGQ DMEQQVVFSM SFVQGEESND KIPVALGLKE KNLYLSCVLK DDKPTLQLES VDPKNYPKKK MEKRFVFNKI EINNKLEFES AQFPNWYIST SQAENMPVFL GGTKGGQDIT DFTMQFVSS; Positive Samples: Mouse liver; Cellular Location: Cytoplasm, Cytoplasmic vesicle, Lysosome, autophagosome, cytosol, exosome Interleukin-1 beta (IL-1 beta) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells
- IL-1 beta is synthesized in response to inflammatory stimuli as a 31 kDa inactive pro-form that accumulates in the cytosol
- Cleavage of pro-IL-1 beta into the active 17 kDa protein requires the activation of inflammasomes, which are multi-protein complexes that respond to pathogens, stress conditions, and other danger signals
- Inflammasome activation triggers the processing of the caspase-1 precursor into its active form, which in turn cleaves pro-IL-1 beta
- IL-1 beta lacks a signal sequence peptide for classical ER/Golgi pathway and is secreted alongside caspase-1 via an alternate and incompletely understood mechanism
- Although IL-1 beta is most often secreted in its active form, secretion of the uncleaved protein may be detectable under some biological conditions
- IL-1 beta signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 alpha
- IL-1 beta activity can be moderated by IL-1 Receptor Antagonist (IL-1RA), a protein produced by many cell types that blocks receptor binding through competitive inhibition
- IL-1 beta play an important role in innate host defense by triggering the production of other proinflammatory cytokines in target cells and initiating acute-phase responses to infection and injury
- Elevated levels of IL-1 beta have been associated with many chronic inflammatory conditions IL-1 beta neutralizing antibodies potential therapeutic value.
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Antigen: IL-1 beta
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL1B
Gene Alias: catabolin, cytokine, Hematopoietin 1 (H1), IFN beta inducing factor, il 1b, IL 1β, IL-1, IL1 B, IL-1 beta, IL-1 precursor, IL1B, IL-1B, IL1B1, IL1beta, IL-1beta, IL1-BETA, IL1F2, IL1β, ILN, Interleukin, interleukin 1 beta, Interleukin 1 beta precursor, interleukin 1, beta, interleukin 1, beta 1, interleukin 1-beta, interleukin*1*beta, Interleukin1 beta, interleukin-1 beta, interleukin-1 beta precursor, interleukin-1 beta precursor (AA -113 to 153), interleukin-1 beta proprotein, interleukin-1b, interleukin-1beta, interleukin-beta, LAF, lymphocyte proliferation-potentiating factor, Osteoclast activating factor (OAF), preinterleukin 1 beta, Pro interleukin 1 beta, prointerleukin-1 beta, pro-interleukin-1-beta
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16176, 24494, 3553
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.97 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P01584, P10749, Q63264
Gene Symbols: IL1B
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-269 of human IL1beta (NP_0005671)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IL-1 beta
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL1B
Gene Alias:
catabolin, cytokine, Hematopoietin 1 (H1), IFN beta inducing factor, il 1b, IL 1β, IL-1, IL1 B, IL-1 beta, IL-1 precursor, IL1B, IL-1B, IL1B1, IL1beta, IL-1beta, IL1-BETA, IL1F2, IL1β, ILN, Interleukin, interleukin 1 beta, Interleukin 1 beta precursor, interleukin 1, beta, interleukin 1, beta 1, interleukin 1-beta, interleukin*1*beta, Interleukin1 beta, interleukin-1 beta, interleukin-1 beta precursor, interleukin-1 beta precursor (AA -113 to 153), interleukin-1 beta proprotein, interleukin-1b, interleukin-1beta, interleukin-beta, LAF, lymphocyte proliferation-potentiating factor, Osteoclast activating factor (OAF), preinterleukin 1 beta, Pro interleukin 1 beta, prointerleukin-1 beta, pro-interleukin-1-beta
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16176, 24494, 3553
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.97 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P01584, P10749, Q63264
Gene Symbols:
IL1B
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-269 of human IL1beta (NP_0005671)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: DAZL
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DAZL
Gene Alias: DAZ homolog, DAZH, DAZL, DAZL1, Dazla, Daz-like, DAZ-like autosomal, deleted in azoospermia like, deleted in azoospermia protein 3, deleted in azoospermia-like, Deleted in azoospermia-like 1, deleted in azoospermia-like protein, germline specific RNA binding protein, HGNC:2685, MGC26406, spermatogenesis gene on the Y-like autosomal, SPGYLA, SPGY-like-autosomal, testis secretory sperm-binding protein Li 204a, Tpx2, Tpx-2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13164, 1618
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.99 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q64368, Q92904
Gene Symbols: DAZL
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 186-295 of human DAZL (NP_0013422)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
DAZL
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DAZL
Gene Alias:
DAZ homolog, DAZH, DAZL, DAZL1, Dazla, Daz-like, DAZ-like autosomal, deleted in azoospermia like, deleted in azoospermia protein 3, deleted in azoospermia-like, Deleted in azoospermia-like 1, deleted in azoospermia-like protein, germline specific RNA binding protein, HGNC:2685, MGC26406, spermatogenesis gene on the Y-like autosomal, SPGYLA, SPGY-like-autosomal, testis secretory sperm-binding protein Li 204a, Tpx2, Tpx-2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13164, 1618
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.99 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q64368, Q92904
Gene Symbols:
DAZL
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 186-295 of human DAZL (NP_0013422)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: MRP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ABCC1
Gene Alias: ABC29, ABCC, Abcc1, Abcc1a, Abcc1b, ATP binding cassette subfamily C member 1, ATP-binding cassette sub-family C ( CFTR/MRP) member 1a, ATP-binding cassette sub-family C member 1, ATP-binding cassette transporter variant ABCC1delta-ex13, ATP-binding cassette transporter variant ABCC1delta-ex13&14, ATP-binding cassette transporter variant ABCC1delta-ex25, ATP-binding cassette transporter variant ABCC1delta-ex25&26, ATP-binding cassette, subfamily C (CFTR/MRP), member 1, ATP-binding cassette, sub-family C (CFTR/MRP), member 1, ATP-binding cassette, sub-family C (CFTR/MRP), member 1a, ATP-binding cassette, sub-family C (CFTR/MRP), member 1b, Avcc1a, DKFZp686N04233, DKFZp781G125, Glutathione-S-conjugate-translocating ATPase ABCC1, GS-X, leuk, leukotriene C(4) transporter, LTC4 transporter, Mdrap, MRP, Mrp1, multidrug resistance protein 1, multidrug resistance-associated protein 1, multiple drug resistance-associated protein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4363
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.06 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P33527
Gene Symbols: ABCC1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 850-960 of human MRP1/ABCC1 (NP_0049872)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MRP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABCC1
Gene Alias:
ABC29, ABCC, Abcc1, Abcc1a, Abcc1b, ATP binding cassette subfamily C member 1, ATP-binding cassette sub-family C ( CFTR/MRP) member 1a, ATP-binding cassette sub-family C member 1, ATP-binding cassette transporter variant ABCC1delta-ex13, ATP-binding cassette transporter variant ABCC1delta-ex13&14, ATP-binding cassette transporter variant ABCC1delta-ex25, ATP-binding cassette transporter variant ABCC1delta-ex25&26, ATP-binding cassette, subfamily C (CFTR/MRP), member 1, ATP-binding cassette, sub-family C (CFTR/MRP), member 1, ATP-binding cassette, sub-family C (CFTR/MRP), member 1a, ATP-binding cassette, sub-family C (CFTR/MRP), member 1b, Avcc1a, DKFZp686N04233, DKFZp781G125, Glutathione-S-conjugate-translocating ATPase ABCC1, GS-X, leuk, leukotriene C(4) transporter, LTC4 transporter, Mdrap, MRP, Mrp1, multidrug resistance protein 1, multidrug resistance-associated protein 1, multiple drug resistance-associated protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4363
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.06 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P33527
Gene Symbols:
ABCC1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 850-960 of human MRP1/ABCC1 (NP_0049872)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Nrf2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NFE2L2
Gene Alias: AI194320, E4TF1-60, E4TF1A, HEBP1, Nfe2l2, NF-E2-related factor 2, NFE2-related factor 2, NF-E2-related factor-2, NFT2, NRF2, NRF2A, nuclear factor (erythroid-derived 2)-like 2, nuclear factor erythroid 2-like 2, nuclear factor erythroid 2-related factor 2, nuclear factor erythroid-derived 2-like 2, nuclear factor, erythroid 2 like 2, nuclear factor, erythroid 2-like 2, nuclear factor, erythroid derived 2, like 2, Unknown (protein for IMAGE:7945830)
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18024, 4780, 83619
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O54968, Q16236, Q60795
Gene Symbols: NFE2L2
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 366-605 of human NRF2 (NP_0061552)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Nrf2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NFE2L2
Gene Alias:
AI194320, E4TF1-60, E4TF1A, HEBP1, Nfe2l2, NF-E2-related factor 2, NFE2-related factor 2, NF-E2-related factor-2, NFT2, NRF2, NRF2A, nuclear factor (erythroid-derived 2)-like 2, nuclear factor erythroid 2-like 2, nuclear factor erythroid 2-related factor 2, nuclear factor erythroid-derived 2-like 2, nuclear factor, erythroid 2 like 2, nuclear factor, erythroid 2-like 2, nuclear factor, erythroid derived 2, like 2, Unknown (protein for IMAGE:7945830)
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18024, 4780, 83619
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
O54968, Q16236, Q60795
Gene Symbols:
NFE2L2
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 366-605 of human NRF2 (NP_0061552)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG