PIPA588262
ISG15 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588262-Each-of-1 | In Stock | ₹ 45,646.26 |
PIPA588262 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
ISG15
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ISG15
Gene Alias
G1P2, hUCRP, IFI15, IGI15, IMD38, interferon, alpha-inducible protein, interferon, alpha-inducible protein (clone IFI-15K), interferon-induced 15 kDa protein, interferon-induced 15-KDa protein, interferon-induced 17 kDa protein, interferon-induced 17-kDa/15-kDa protein, interferon-stimulated protein (15 kDa), interferon-stimulated protein 15, interferon-stimulated protein, 15 kDa, IP17, Irfp, Isg15, ISG15 ubiquitin like modifier, ISG15 ubiquitin-like modifier, ubiquitin cross-reactive protein, Ubiquitin-like protein ISG15, UCRP
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
298693, 9636
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.74 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
P05161
Gene Symbols
ISG15
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human ISG15 (NP_0050921)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MGWDLTVKML AGNEFQVSLS SSMSVSELKA QITQKIGVHA FQQRLAVHPS GVALQDRVPL ASQGLGPGST VLLVVDKCDE PLSILVRNNK GRSSTYEVRL TQTVAHLKQQ VSGLEGVQDD LFWLTFEGKP LEDQLPLGEY GLKPLSTVFM NLRLRGGGTE PGGRS; Positive Samples: HeLa, PC-3, SW620, HCT116; Cellular Location: Cytoplasm Ubiquitin-like protein ISG15 plays a key role in the innate immune response to viral infection either via its conjugation to a target protein (ISGylation) or via its action as a free or unconjugated protein
- It is secreted from monocytes in response to type I interferons and causes natural killer (NK)-cell proliferation and an augmentation of non-MCH (major histocompatibility complex)-restricted cytotoxicity
- Synthesis is stimulated by IFN-alpha or IFN-beta or IFN-omega, but not IFN-gamma
- ISG15 expression is also induced by overexpression of interferon regulatory factors that participate in transcriptional regulation of IFN genes, and by influenza B virus
- ISG15 is secreted by cell lines of monocyte, T-lymphocyte, B-lymphocyte, human fibroblasts, and epithelial origins
- Enhancement of NK cell proliferation, augmentation of non-major histocompatibility complex-restricted cytotoxicity, and induction of IFN-gamma from T cells identify ISG15 as a member of the cytokine cascade and suggest that it may be responsible for amplifying and directing some of the immunomodulatory effects of IFN-alpha or IFN-beta
- ISG15 has has also been shown to function intracellularly as a ubiquitin homolog
- Mutations affecting the gene can result in Immunodeficiency 38, with basal ganglia calcification (IMD38).
Compare Similar Items
Show Difference
Antigen: ISG15
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ISG15
Gene Alias: G1P2, hUCRP, IFI15, IGI15, IMD38, interferon, alpha-inducible protein, interferon, alpha-inducible protein (clone IFI-15K), interferon-induced 15 kDa protein, interferon-induced 15-KDa protein, interferon-induced 17 kDa protein, interferon-induced 17-kDa/15-kDa protein, interferon-stimulated protein (15 kDa), interferon-stimulated protein 15, interferon-stimulated protein, 15 kDa, IP17, Irfp, Isg15, ISG15 ubiquitin like modifier, ISG15 ubiquitin-like modifier, ubiquitin cross-reactive protein, Ubiquitin-like protein ISG15, UCRP
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 298693, 9636
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.74 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P05161
Gene Symbols: ISG15
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human ISG15 (NP_0050921)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ISG15
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ISG15
Gene Alias:
G1P2, hUCRP, IFI15, IGI15, IMD38, interferon, alpha-inducible protein, interferon, alpha-inducible protein (clone IFI-15K), interferon-induced 15 kDa protein, interferon-induced 15-KDa protein, interferon-induced 17 kDa protein, interferon-induced 17-kDa/15-kDa protein, interferon-stimulated protein (15 kDa), interferon-stimulated protein 15, interferon-stimulated protein, 15 kDa, IP17, Irfp, Isg15, ISG15 ubiquitin like modifier, ISG15 ubiquitin-like modifier, ubiquitin cross-reactive protein, Ubiquitin-like protein ISG15, UCRP
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
298693, 9636
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.74 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P05161
Gene Symbols:
ISG15
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human ISG15 (NP_0050921)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PML
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PML
Gene Alias: 1200009E24Rik, AI661194, MYL, Pml, PML/RARA fusion, pml1, PP8675, probable transcription factor PML, promyelocytic leukemia, promyelocytic leukemia protein, promyelocytic leukemia, inducer of, protein PML, RGD1562602, RING finger protein 71, RNF71, TRIM19, tripartite motif protein TRIM19, tripartite motif-containing protein 19
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5371
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration: 2.42 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P29590
Gene Symbols: PML
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human PML (NP_1502412)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PML
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PML
Gene Alias:
1200009E24Rik, AI661194, MYL, Pml, PML/RARA fusion, pml1, PP8675, probable transcription factor PML, promyelocytic leukemia, promyelocytic leukemia protein, promyelocytic leukemia, inducer of, protein PML, RGD1562602, RING finger protein 71, RNF71, TRIM19, tripartite motif protein TRIM19, tripartite motif-containing protein 19
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5371
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration:
2.42 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P29590
Gene Symbols:
PML
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human PML (NP_1502412)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CD8
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CD8B
Gene Alias: BB154331, CD8, CD8 alpha, CD8 alpha chain, CD8 alpha chain precursor, CD8 antigen, CD8 antigen 32 kDa chain, CD8 antigen 37 kDa chain, CD8 antigen alpha polypeptide, CD8 antigen alpha protein, CD8 antigen alpha protein precursor, CD8 antigen alpha-chain, CD8 antigen beta polypeptide, CD8 antigen beta polypeptide precursor, CD8 antigen beta-chain, CD8 antigen, alpha chain, CD8 antigen, alpha polypeptide, CD8 antigen, alpha polypeptide (p32), CD8 antigen, alpha-chain, CD8 antigen, beta chain, CD8 antigen, beta chain 1, CD8 antigen, beta polypeptide, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta-chain, CD8 beta, CD8 beta chain, CD8 beta-2, CD8a, CD8A antigen alpha, CD8a molecule, CD8A, T-cell surface glycoprotein, CD8alpha, CD8B, CD8b antigen, CD8b molecule, CD8b molecule pseudogene, Cd8b1, CD8beta, CD8BP, fCD8, LEU2, Leu-2, Leu2 T-lymphocyte antigen, leu-2a, Ly-2, LY3, Ly-3, Ly-35, Ly-B, Ly-C, Lymphocyte antigen 3, Lyt2, Lyt-2, Lyt-2.1 lymphocyte differentiation antigen (AA at 100), Lyt3, Lyt-3, MAL, membrane glycoprotein, membrane protein, OKT8 T-cell antigen, OX-8 membrane antigen, p32, P37, RHACD8-4, T cell co-receptor, T lymphocyte surface glycoprotein beta chain, T8 T-cell antigen, T-cell antigen Leu2, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein Lyt-2, T-cell surface glycoprotein Lyt-3, T-cell surface molecule, T-lymphocyte differentiation antigen T8/Leu-2, type I transmembrane glycoprotein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12525, 12526, 925, 926
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration: 2.59 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P01731, P01732, P10300, P10966
Gene Symbols: Cd8a, CD8B, Cd8b1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-182 of human CD8A (NP_001759.3).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CD8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CD8B
Gene Alias:
BB154331, CD8, CD8 alpha, CD8 alpha chain, CD8 alpha chain precursor, CD8 antigen, CD8 antigen 32 kDa chain, CD8 antigen 37 kDa chain, CD8 antigen alpha polypeptide, CD8 antigen alpha protein, CD8 antigen alpha protein precursor, CD8 antigen alpha-chain, CD8 antigen beta polypeptide, CD8 antigen beta polypeptide precursor, CD8 antigen beta-chain, CD8 antigen, alpha chain, CD8 antigen, alpha polypeptide, CD8 antigen, alpha polypeptide (p32), CD8 antigen, alpha-chain, CD8 antigen, beta chain, CD8 antigen, beta chain 1, CD8 antigen, beta polypeptide, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta-chain, CD8 beta, CD8 beta chain, CD8 beta-2, CD8a, CD8A antigen alpha, CD8a molecule, CD8A, T-cell surface glycoprotein, CD8alpha, CD8B, CD8b antigen, CD8b molecule, CD8b molecule pseudogene, Cd8b1, CD8beta, CD8BP, fCD8, LEU2, Leu-2, Leu2 T-lymphocyte antigen, leu-2a, Ly-2, LY3, Ly-3, Ly-35, Ly-B, Ly-C, Lymphocyte antigen 3, Lyt2, Lyt-2, Lyt-2.1 lymphocyte differentiation antigen (AA at 100), Lyt3, Lyt-3, MAL, membrane glycoprotein, membrane protein, OKT8 T-cell antigen, OX-8 membrane antigen, p32, P37, RHACD8-4, T cell co-receptor, T lymphocyte surface glycoprotein beta chain, T8 T-cell antigen, T-cell antigen Leu2, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein Lyt-2, T-cell surface glycoprotein Lyt-3, T-cell surface molecule, T-lymphocyte differentiation antigen T8/Leu-2, type I transmembrane glycoprotein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12525, 12526, 925, 926
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration:
2.59 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P01731, P01732, P10300, P10966
Gene Symbols:
Cd8a, CD8B, Cd8b1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-182 of human CD8A (NP_001759.3).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: K-Ras
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KRAS
Gene Alias: AI929937, cellular c-Ki-ras2, cellular c-Ki-ras2 proto-oncogene, CFC2, c-Ki-ras, c-Kirsten-ras protein, c-Kirsten-ras proto-oncogene, c-K-ras, c-K-ras2 protein, fa04e08, fc14b12, fc23g10, fj89d12, GTPase KRas, GTPase KRas, N-terminally processed, hypothetical protein LOC445289, K RAS, ki-Ras, Kirsten rat sarcoma oncogene 2, expressed, Kirsten rat sarcoma viral (Kras-2) oncogene homolog, Kirsten rat sarcoma viral oncogene, Kirsten rat sarcoma viral oncogene homolog, Kirsten rat sarcoma viral oncogene homologue 2 (active), KRAS, K-ras, K-Ras 2, K-ras p21 protein, KRAS proto-oncogene, GTPase, KRAS1, Kras2, Kras-2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, NS, NS3, oncogene KRAS2, p21, p21 protein, p21B, p21ras, PR310 c-K-ras oncogene, RALD, ras, ras p21, RASK, RASK2, ras-like protein, transforming protein p21, Unknown, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, wu:fa04e08, wu:fc14b12, wu:fc23g10, wu:fj89d12, xRAS2, zgc:85725
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16653, 24525, 3845
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot, Immunoprecipitation, Western Blot
Concentration: 1.51 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P01116, P08644, P32883
Gene Symbols: KRAS
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 30-189 of human KRAS (NP_2035241)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
K-Ras
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KRAS
Gene Alias:
AI929937, cellular c-Ki-ras2, cellular c-Ki-ras2 proto-oncogene, CFC2, c-Ki-ras, c-Kirsten-ras protein, c-Kirsten-ras proto-oncogene, c-K-ras, c-K-ras2 protein, fa04e08, fc14b12, fc23g10, fj89d12, GTPase KRas, GTPase KRas, N-terminally processed, hypothetical protein LOC445289, K RAS, ki-Ras, Kirsten rat sarcoma oncogene 2, expressed, Kirsten rat sarcoma viral (Kras-2) oncogene homolog, Kirsten rat sarcoma viral oncogene, Kirsten rat sarcoma viral oncogene homolog, Kirsten rat sarcoma viral oncogene homologue 2 (active), KRAS, K-ras, K-Ras 2, K-ras p21 protein, KRAS proto-oncogene, GTPase, KRAS1, Kras2, Kras-2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, NS, NS3, oncogene KRAS2, p21, p21 protein, p21B, p21ras, PR310 c-K-ras oncogene, RALD, ras, ras p21, RASK, RASK2, ras-like protein, transforming protein p21, Unknown, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, wu:fa04e08, wu:fc14b12, wu:fc23g10, wu:fj89d12, xRAS2, zgc:85725
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16653, 24525, 3845
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot, Immunoprecipitation, Western Blot
Concentration:
1.51 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P01116, P08644, P32883
Gene Symbols:
KRAS
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 30-189 of human KRAS (NP_2035241)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG