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PIPA588265

CD8 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA588265-Each-of-1 In Stock ₹ 44,619.54

PIPA588265 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

CD8

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CD8B

Gene Alias

BB154331, CD8, CD8 alpha, CD8 alpha chain, CD8 alpha chain precursor, CD8 antigen, CD8 antigen 32 kDa chain, CD8 antigen 37 kDa chain, CD8 antigen alpha polypeptide, CD8 antigen alpha protein, CD8 antigen alpha protein precursor, CD8 antigen alpha-chain, CD8 antigen beta polypeptide, CD8 antigen beta polypeptide precursor, CD8 antigen beta-chain, CD8 antigen, alpha chain, CD8 antigen, alpha polypeptide, CD8 antigen, alpha polypeptide (p32), CD8 antigen, alpha-chain, CD8 antigen, beta chain, CD8 antigen, beta chain 1, CD8 antigen, beta polypeptide, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta-chain, CD8 beta, CD8 beta chain, CD8 beta-2, CD8a, CD8A antigen alpha, CD8a molecule, CD8A, T-cell surface glycoprotein, CD8alpha, CD8B, CD8b antigen, CD8b molecule, CD8b molecule pseudogene, Cd8b1, CD8beta, CD8BP, fCD8, LEU2, Leu-2, Leu2 T-lymphocyte antigen, leu-2a, Ly-2, LY3, Ly-3, Ly-35, Ly-B, Ly-C, Lymphocyte antigen 3, Lyt2, Lyt-2, Lyt-2.1 lymphocyte differentiation antigen (AA at 100), Lyt3, Lyt-3, MAL, membrane glycoprotein, membrane protein, OKT8 T-cell antigen, OX-8 membrane antigen, p32, P37, RHACD8-4, T cell co-receptor, T lymphocyte surface glycoprotein beta chain, T8 T-cell antigen, T-cell antigen Leu2, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein Lyt-2, T-cell surface glycoprotein Lyt-3, T-cell surface molecule, T-lymphocyte differentiation antigen T8/Leu-2, type I transmembrane glycoprotein

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12525, 12526, 925, 926

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot, Western Blot

Concentration

2.59 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.

P01731, P01732, P10300, P10966

Gene Symbols

Cd8a, CD8B, Cd8b1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 22-182 of human CD8A (NP_001759.3).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: SQFRVSPLDR TWNLGETVEL KCQVLLSNPT SGCSWLFQPR GAAASPTFLL YLSQNKPKAA EGLDTQRFSG KRLGDTFVLT LSDFRRENEG YYFCSALSNS IMYFSHFVPV FLPAKPTTTP APRPPTPAPT IASQPLSLRP EACRPAAGGA VHTRGLDFAC D Positive Samples: Mouse pancreas; Cellular Location: Cell membrane, Single-pass type I membrane protein Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation
  • CD8 is predominantly expressed on T cells as a disulfide-linked heterodimer of CD8alpha and CD8beta, where it functions as a co-receptor, along with T cell receptor (TCR), for major histocompatibilty complex class I (MHC-I) molecules; whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules
  • CD8 exists on the cell surface, where the CD8alpha chain is essential for binding to MHC-I
  • CD8 is also expressed on a subset of T cells, NK cells, monocytes and dendritic cells as disulfide-linked homodimers of CD8alpha
  • Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation
  • Once activated, CTLs play a crucial role in the clearance of pathogens and tumor cells
  • Differentiation of naive CD8+ T cells into CTLs is strongly enhanced by IL-2, IL-12 and TGF-beta1.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA588265

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Antigen:
CD8
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CD8B
Gene Alias:
BB154331, CD8, CD8 alpha, CD8 alpha chain, CD8 alpha chain precursor, CD8 antigen, CD8 antigen 32 kDa chain, CD8 antigen 37 kDa chain, CD8 antigen alpha polypeptide, CD8 antigen alpha protein, CD8 antigen alpha protein precursor, CD8 antigen alpha-chain, CD8 antigen beta polypeptide, CD8 antigen beta polypeptide precursor, CD8 antigen beta-chain, CD8 antigen, alpha chain, CD8 antigen, alpha polypeptide, CD8 antigen, alpha polypeptide (p32), CD8 antigen, alpha-chain, CD8 antigen, beta chain, CD8 antigen, beta chain 1, CD8 antigen, beta polypeptide, CD8 antigen, beta polypeptide 1 (p37), CD8 antigen, beta-chain, CD8 beta, CD8 beta chain, CD8 beta-2, CD8a, CD8A antigen alpha, CD8a molecule, CD8A, T-cell surface glycoprotein, CD8alpha, CD8B, CD8b antigen, CD8b molecule, CD8b molecule pseudogene, Cd8b1, CD8beta, CD8BP, fCD8, LEU2, Leu-2, Leu2 T-lymphocyte antigen, leu-2a, Ly-2, LY3, Ly-3, Ly-35, Ly-B, Ly-C, Lymphocyte antigen 3, Lyt2, Lyt-2, Lyt-2.1 lymphocyte differentiation antigen (AA at 100), Lyt3, Lyt-3, MAL, membrane glycoprotein, membrane protein, OKT8 T-cell antigen, OX-8 membrane antigen, p32, P37, RHACD8-4, T cell co-receptor, T lymphocyte surface glycoprotein beta chain, T8 T-cell antigen, T-cell antigen Leu2, T-cell membrane glycoprotein Ly-3, T-cell surface glycoprotein, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 beta chain, T-cell surface glycoprotein Lyt-2, T-cell surface glycoprotein Lyt-3, T-cell surface molecule, T-lymphocyte differentiation antigen T8/Leu-2, type I transmembrane glycoprotein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12525, 12526, 925, 926
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration:
2.59 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P01731, P01732, P10300, P10966
Gene Symbols:
Cd8a, CD8B, Cd8b1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-182 of human CD8A (NP_001759.3).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA588269

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Antigen:
K-Ras
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KRAS
Gene Alias:
AI929937, cellular c-Ki-ras2, cellular c-Ki-ras2 proto-oncogene, CFC2, c-Ki-ras, c-Kirsten-ras protein, c-Kirsten-ras proto-oncogene, c-K-ras, c-K-ras2 protein, fa04e08, fc14b12, fc23g10, fj89d12, GTPase KRas, GTPase KRas, N-terminally processed, hypothetical protein LOC445289, K RAS, ki-Ras, Kirsten rat sarcoma oncogene 2, expressed, Kirsten rat sarcoma viral (Kras-2) oncogene homolog, Kirsten rat sarcoma viral oncogene, Kirsten rat sarcoma viral oncogene homolog, Kirsten rat sarcoma viral oncogene homologue 2 (active), KRAS, K-ras, K-Ras 2, K-ras p21 protein, KRAS proto-oncogene, GTPase, KRAS1, Kras2, Kras-2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, NS, NS3, oncogene KRAS2, p21, p21 protein, p21B, p21ras, PR310 c-K-ras oncogene, RALD, ras, ras p21, RASK, RASK2, ras-like protein, transforming protein p21, Unknown, v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog, v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, wu:fa04e08, wu:fc14b12, wu:fc23g10, wu:fj89d12, xRAS2, zgc:85725
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16653, 24525, 3845
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot, Immunoprecipitation, Western Blot
Concentration:
1.51 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P01116, P08644, P32883
Gene Symbols:
KRAS
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 30-189 of human KRAS (NP_2035241)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA588271

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Antigen:
VEGFD
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
VEGFD
Gene Alias:
AI325264, c-fos induced growth factor, c-fos induced growth factor (vascular endothelial growth factor D), c-fos-induced growth factor, FIGF, Vascular endothelial growth factor D, vascular endothelial growth factor-D, VEGF4, VEGFD, VEGF-D, VEGFR2 and -3 ligand
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2277
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.74 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O43915
Gene Symbols:
VEGFD
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-220 of human VEGF-D (NP_0044601)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG

Img

Thermo Scientific

PIPA588272

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Antigen:
PDGF-BB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDGFB
Gene Alias:
becaplermin, c-sis, FLJ12858, H-PDGF-BB, IBGC5, PDGF, pdgf protein, PDGF subunit B, PDGF, B chain, PDGF2, PDGF-2, PDGFB, PDGF-B, platelet derived growth factor subunit B, platelet derived growth factor, B polypeptide, platelet-derived growth factor 2, platelet-derived growth factor B, platelet-derived growth factor B chain, platelet-derived growth factor beta, platelet-derived growth factor beta polypeptide, platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog), platelet-derived growth factor subunit B, platelet-derived growth factor, beta polypeptide (oncogene SIS), Platelet-derived growth factor, same as Sis (Simian sarcoma viral oncogene homologue, c-sis), proto-oncogene c-Sis, Sis, SSV
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
24628, 5155
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.22 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P01127, Q05028
Gene Symbols:
PDGFB
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 140-241 of human PDGFB (NP_0025991)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat, Rat
Product Type:
Antibody
Isotype:
IgG