PIPA587657

HLA-C Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587657-Each-of-1 In Stock ₹ 44,705.10

PIPA587657 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

HLA-C

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HLA-C

Gene Alias

alpha chain of MHC class II, D6S204, HLA C, HLA class I histocompatibility antigen C alpha chain, HLA class I histocompatibility antigen Cw-1 alpha chain, HLA class I histocompatibility antigen, C alpha chain, HLA class I histocompatibility antigen, Cw-1 alpha chain, HLA class I histocompatibility antigen, Cw-15 alpha chain, HLA class I histocompatibility antigen, Cw-18 alpha chain, HLAC, HLA-C, HLA-C alpha chain, HLA-C alpha chain (HLA-Cw*15v), HLA-C alpha chain for Cw*18GB, HLA-C alpha-chain, HLA-C antigen, HLA-Cw, HLA-Cw*04GB, HLA-Cw*1702, HLA-Cw*18GB, HLA-Cw-1503, HLA-JY3, HLC-C, Human leukocyte antigen C, human leukocyte antigen-C alpha chain, leukocyte antigen C, major histocompatibility antigen HLA-C, major histocompatibility complex, class I, C, MHC, MHC clas I antigen, MHC class 1 antigen, MHC Class I antigen, MHC class I antigen Cw*15, MHC class I antigen Cw*18, MHC class I antigen heavy chain HLA-C, MHC class I histocompatibility antigen, MHC class I molecule, MHC class II antigen, PSORS1, surface antigen, truncated MHC class I antigen

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3107

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.93 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P10321

Gene Symbols

HLA-C

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 25-308 of human HLA-C (P30499)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: LO2, HL-60, BT-474, Jurkat, Mouse liver; Cellular Location: Membrane, Single-pass type I membrane protein Immunogen sequence: CSHSMKYFFT SVSRPGRGEP RFISVGYVDD TQFVRFDSDA ASPRGEPRAP WVEQEGPEYW DRETQKYNRQ AQTDRVSLRN LRGYYNQSEA GSHTLQWMCG CDLGPDGRLL RGYDQYAYDG KDYIALNEDL RSWTAADTAA QITQRKWEAA REAEERRAYL EGTCVEWLRR YLENGKESLQ RAEHPKTHVT HHPVSDHEAT LRCWALGFYP AEITLTWQWD GEDQTQDTEL VETRPAGDGT FQKWAAVMVP SGEEQRYTCH VQHEGLPEPL TLRWEPSSQP TIPI HLA-C belongs to the HLA class I heavy chain paralogues
  • This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin)
  • The heavy chain is anchored in the membrane
  • Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen
  • They are expressed in nearly all cells
  • The heavy chain is approximately 45 kDa and its gene contains 8 exons
  • Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail
  • Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule
  • Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation
  • Over one hundred HLA-C alleles have been described
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA587657

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Antigen:
HLA-C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLA-C

Gene Alias:
alpha chain of MHC class II, D6S204, HLA C, HLA class I histocompatibility antigen C alpha chain, HLA class I histocompatibility antigen Cw-1 alpha chain, HLA class I histocompatibility antigen, C alpha chain, HLA class I histocompatibility antigen, Cw-1 alpha chain, HLA class I histocompatibility antigen, Cw-15 alpha chain, HLA class I histocompatibility antigen, Cw-18 alpha chain, HLAC, HLA-C, HLA-C alpha chain, HLA-C alpha chain (HLA-Cw*15v), HLA-C alpha chain for Cw*18GB, HLA-C alpha-chain, HLA-C antigen, HLA-Cw, HLA-Cw*04GB, HLA-Cw*1702, HLA-Cw*18GB, HLA-Cw-1503, HLA-JY3, HLC-C, Human leukocyte antigen C, human leukocyte antigen-C alpha chain, leukocyte antigen C, major histocompatibility antigen HLA-C, major histocompatibility complex, class I, C, MHC, MHC clas I antigen, MHC class 1 antigen, MHC Class I antigen, MHC class I antigen Cw*15, MHC class I antigen Cw*18, MHC class I antigen heavy chain HLA-C, MHC class I histocompatibility antigen, MHC class I molecule, MHC class II antigen, PSORS1, surface antigen, truncated MHC class I antigen

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3107

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.93 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P10321

Gene Symbols:
HLA-C

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-308 of human HLA-C (P30499)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587659

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Antigen:
P2X6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
P2RX6

Gene Alias:
ATP receptor, P2RX6, P2RXL1, P2X purinoceptor 6, P2x6, P2X6 receptor, P2XM, Purinergic receptor, purinergic receptor P2X 6, purinergic receptor P2X, ligand gated ion channel, 6, purinergic receptor P2X, ligand-gated ion channel, 6, purinergic receptor P2X6, Purinergic receptor P2X-like 1, purinergic receptor P2X-like 1 orphan receptor, purinergic receptor P2X-like 1, orphan receptor, purinoceptor P2X6, purinoreceptor P2X6, Rnap2x6, skeletal muscle-expressed P2X

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18440

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.47 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O54803

Gene Symbols:
P2RX6

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human P2RX6 (NP_0011530261)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587660

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Antigen:
TMPRSS11D

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMPRSS11D

Gene Alias:
Adrenal secretory serine protease, airway spesific trypsin-like protease, airway trypsin like protease, airway trypsin-like protease, AsP, AST, AT, BC020151, HAT, Mat, MGC150587, MGC150588, Rat, TMPRSS11D, Transmembrane protease serine 11D, Transmembrane protease serine 11D catalytic chain, Transmembrane protease serine 11D non-catalytic chain, transmembrane protease, serine 11D, transmembrane serine protease 11D

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
231382, 64565, 9407

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.24 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O60235, Q8VHJ4, Q8VHK8

Gene Symbols:
TMPRSS11D

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 42-292 of human TMPRSS11D (NP_0042531)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587661

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Antigen:
CIR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CIR1

Gene Alias:
1700023b02rik, 2810021A19Rik, CBF1 (RBPJ) interacting corepressor 1, CBF1 interacting corepressor, CBF1-interacting corepressor, Cicr, Cir, CIR1, Corepressor interacting with RBPJ 1, corepressor interacting with RBPJ, 1, corepressor interacting with RBPJ, CIR1, recepin, RGD1309199

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9541

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.22 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q86X95

Gene Symbols:
CIR1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human CIR1 (NP_0048733)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG