PIPA585373
CD11a Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585373-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA585373 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
CD11a
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ITGAL
Gene Alias
(p180), alpha L integrin, antigen CD11A (p180), antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide, antigen CD11A p180, CD11 antigen-like family member A, CD11a, integrin alpha L, integrin alphaL, integrin alpha-L, integrin alpha-L precursor, integrin gene promoter, integrin subunit alpha L, integrin surface receptor, integrin, alpha L, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide), ITGAL, Leukocyte adhesion glycoprotein LFA-1 alpha chain, leukocyte function-associated molecule 1 alpha chain, LFA-1, LFA-1 alpha, LFA1A, LFA-1A, Ly-15, Ly-21, lymphocyte antigen 15, lymphocyte function associated antigen 1, alpha polypeptide, lymphocyte function-associated antigen 1, lymphocyte function-associated antigen 1, alpha polypeptide, lymphocyte function-associated antigen-1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3683
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot, Western Blot
Concentration
0.87 mg/mL
Formulation
0.1M tris glycine with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.
P20701
Gene Symbols
ITGAL
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human CD11a.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Keep as concentrated solution
- Predicted reactivity: Sheep (84%), Chimpanzee (97%), Bovine (83%)
- Positive Control: THP-1
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- CD11a (LFA-1 alpha, ITGAL) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin
- CD11a is implicated in activation of LFA-1 complex
- CD11a plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling
- CD11a is expressed on the plasma membrane of leukocytes in a low-affinity conformation
- Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of CD11a to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3
- CD11a is thus involved in interaction of various immune cells and in their tissue-specific settlement, but participates also in control of cell differentiation and proliferation and of T-cell effector functions
- Blocking of CD11a function by specific antibodies or small molecules has become an important therapeutic approach in treatment of multiple inflammatory diseases
- For example, humanized anti- CD11a antibody Efalizumab (Raptiva) is being used to interfere with T cell migration to sites of inflammation, binding of cholesterol-lowering drug simvastatin to CD11a allosteric site leads to immunomodulation and increase in lymphocytic cholinergic activity
- Two transcript variants encoding different isoforms of CD11a have been found
- Diseases associated with CD11a dysfunction include benign cephalic histiocytosis and leukocyte adhesion deficiency.
Compare Similar Items
Show Difference
Antigen: CD11a
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ITGAL
Gene Alias: (p180), alpha L integrin, antigen CD11A (p180), antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide, antigen CD11A p180, CD11 antigen-like family member A, CD11a, integrin alpha L, integrin alphaL, integrin alpha-L, integrin alpha-L precursor, integrin gene promoter, integrin subunit alpha L, integrin surface receptor, integrin, alpha L, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide), ITGAL, Leukocyte adhesion glycoprotein LFA-1 alpha chain, leukocyte function-associated molecule 1 alpha chain, LFA-1, LFA-1 alpha, LFA1A, LFA-1A, Ly-15, Ly-21, lymphocyte antigen 15, lymphocyte function associated antigen 1, alpha polypeptide, lymphocyte function-associated antigen 1, lymphocyte function-associated antigen 1, alpha polypeptide, lymphocyte function-associated antigen-1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3683
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot, Western Blot
Concentration: 0.87 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.: P20701
Gene Symbols: ITGAL
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human CD11a.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CD11a
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ITGAL
Gene Alias:
(p180), alpha L integrin, antigen CD11A (p180), antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide, antigen CD11A p180, CD11 antigen-like family member A, CD11a, integrin alpha L, integrin alphaL, integrin alpha-L, integrin alpha-L precursor, integrin gene promoter, integrin subunit alpha L, integrin surface receptor, integrin, alpha L, integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide), ITGAL, Leukocyte adhesion glycoprotein LFA-1 alpha chain, leukocyte function-associated molecule 1 alpha chain, LFA-1, LFA-1 alpha, LFA1A, LFA-1A, Ly-15, Ly-21, lymphocyte antigen 15, lymphocyte function associated antigen 1, alpha polypeptide, lymphocyte function-associated antigen 1, lymphocyte function-associated antigen 1, alpha polypeptide, lymphocyte function-associated antigen-1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3683
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot, Western Blot
Concentration:
0.87 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.:
P20701
Gene Symbols:
ITGAL
Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human CD11a.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PAX6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PAX6
Gene Alias: 1500038E17Rik, AEY11, AN, AN2, Aniridia, aniridia type II protein, D11S812E, Dey, Dickie's small eye, FVH1, Gsfaey11, Keratitis, MGC17209, MGDA, oculorhombin, paired box 6, paired box gene 6, Paired Box Gene-6, paired box homeotic gene 6, paired box homeotic gene-6, paired box protein Pax-6, Pax6, Pax-6, PAX6 protein, Sey, small eye, transcription factor, WAGR
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18508, 25509, 5080
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1.28 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: P26367, P63015, P63016
Gene Symbols: PAX6
Immunogen: Recombinant protein encompassing a sequence within the center region of human PAX6.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PAX6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PAX6
Gene Alias:
1500038E17Rik, AEY11, AN, AN2, Aniridia, aniridia type II protein, D11S812E, Dey, Dickie's small eye, FVH1, Gsfaey11, Keratitis, MGC17209, MGDA, oculorhombin, paired box 6, paired box gene 6, Paired Box Gene-6, paired box homeotic gene 6, paired box homeotic gene-6, paired box protein Pax-6, Pax6, Pax-6, PAX6 protein, Sey, small eye, transcription factor, WAGR
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18508, 25509, 5080
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1.28 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
P26367, P63015, P63016
Gene Symbols:
PAX6
Immunogen:
Recombinant protein encompassing a sequence within the center region of human PAX6.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: c-Rel
Classification: Polyclonal
Conjugate: Unconjugated
Gene: REL
Gene Alias: BCD541; C-Rel; C-Rel protein; C-Rel proto-oncogene protein; gemin 1; gemin-1; LOW QUALITY PROTEIN: proto-oncogene c-Rel; oncogene REL, avian reticuloendotheliosis; proto-oncogene c-Rel; REL; REL proto-oncogene, NF-kB subunit; reticuloendotheliosis oncogene; SMA; SMA1; SMA2; SMA3; SMA4; SMN; SMN2; SMNT; v-rel avian reticuloendotheliosis viral oncogene homolog; v-rel reticuloendotheliosis viral oncogene homolog
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5966
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q04864
Gene Symbols: REL
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human c-Rel.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
c-Rel
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
REL
Gene Alias:
BCD541; C-Rel; C-Rel protein; C-Rel proto-oncogene protein; gemin 1; gemin-1; LOW QUALITY PROTEIN: proto-oncogene c-Rel; oncogene REL, avian reticuloendotheliosis; proto-oncogene c-Rel; REL; REL proto-oncogene, NF-kB subunit; reticuloendotheliosis oncogene; SMA; SMA1; SMA2; SMA3; SMA4; SMN; SMN2; SMNT; v-rel avian reticuloendotheliosis viral oncogene homolog; v-rel reticuloendotheliosis viral oncogene homolog
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5966
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q04864
Gene Symbols:
REL
Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human c-Rel.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: SHC
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SHC1
Gene Alias: FLJ26504; OTTHUMP00000035472; p66; P66shc; RP11-307C12.1; SH2 domain protein C1; SHC; SHC (Src homology 2 domain containing) transforming protein 1; SHC (Src homology 2 domain-containing) transforming protein 1; SHC adaptor protein 1; SHC1; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; src homology 2 domain-containing transforming protein C1; src homology 2 domain-containing-transforming protein C1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20416, 6464
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: P29353, P98083
Gene Symbols: SHC1
Immunogen: Recombinant protein encompassing a sequence within the center region of human SHC1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SHC
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SHC1
Gene Alias:
FLJ26504; OTTHUMP00000035472; p66; P66shc; RP11-307C12.1; SH2 domain protein C1; SHC; SHC (Src homology 2 domain containing) transforming protein 1; SHC (Src homology 2 domain-containing) transforming protein 1; SHC adaptor protein 1; SHC1; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; src homology 2 domain-containing transforming protein C1; src homology 2 domain-containing-transforming protein C1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20416, 6464
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
P29353, P98083
Gene Symbols:
SHC1
Immunogen:
Recombinant protein encompassing a sequence within the center region of human SHC1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG