PIPA585456

SKA1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585456-Each-of-1 In Stock ₹ 45,047.34

PIPA585456 - Each of 1

₹ 45,047.34

In Stock

Quantity

1

Base Price: ₹ 45,047.34

GST (18%): ₹ 8,108.521

Total Price: ₹ 53,155.861

Antigen

SKA1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SKA1

Gene Alias

2810433K01Rik, AV117428, C18orf24, RGD1310784, SKA1, spindle and kinetochore associated complex subunit 1, spindle and kinetochore-associated protein 1, spindle and KT (kinetochore) associated 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

220134, 291441, 66468

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.

B0BN28, Q96BD8, Q9CPV1

Gene Symbols

SKA1

Immunogen

Recombinant protein encompassing a sequence within the center region of human SKA1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Keep as concentrated solution
  • Predicted reactivity: Rhesus Monkey (94%), Bovine (87%)
  • Positive Control: Target recombinant protein
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Upon entry into mitosis, the cell's microtubule (MT) network forms the mitotic spindle, allowing the segregation of paired chromosomes
  • Proteinaceous structures on centromeric chromatin termed kinetochores (KT) are essential for the proper attachment of the chromosomes to the spindle MTs
  • A recently discovered spindle and kinetochore complex, comprised of proteins SKA1, SKA2, and SKA3, has been found to be required for stable KT-MT interactions and timely anaphase onset
  • Depletion of either SKA1 or SKA2 by siRNA results in the loss of both proteins from the KT, but does not impact overall KT structure
  • Cells depleted of the SKA complex undergo a prolonged checkpoint-dependent delay in a metaphase-like state, indicating the importance of the SKA complex in the maintenance of the metaphase plate and spindle checkpoint silencing.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA585456

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Antigen:
SKA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SKA1

Gene Alias:
2810433K01Rik, AV117428, C18orf24, RGD1310784, SKA1, spindle and kinetochore associated complex subunit 1, spindle and kinetochore-associated protein 1, spindle and KT (kinetochore) associated 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
220134, 291441, 66468

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
B0BN28, Q96BD8, Q9CPV1

Gene Symbols:
SKA1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human SKA1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585459

--


Antigen:
KANSL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KANSL1

Gene Alias:
1700081L11Rik, 9430041J06Rik, CENP-36, centromere protein 36, centromere protein 36 antibody, DKFZp686P06109 antibody, DKFZp727C091 antibody, hMSL1v1, Kansl1, KAT8 regulatory NSL complex subunit 1, KAT8 regulatory NSL complex subunit 1 antibody, KDVS, KIAA1267, KIAA1267 antibody, male-specific lethal 1 homolog, MGC102843 antibody, mKIAA1267, MLL1/MLL complex subunit KANSL1, MLL1/MLL complex subunit male-specific lethal 1 homolog antibody, MSL1 homolog 1, MSL1V1, MSL1v1 antibody, non-specific lethal 1 homolog, NSL complex protein NSL1, NSL1, RGD1311429

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
284058

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.82 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal, pH 7

Gene Accession No.:
Q7Z3B3

Gene Symbols:
KANSL1

Immunogen:
Recombinant protein encompassing a sequence within the N-terminus region of human KIAA1267.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585460

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Antigen:
EFCAB4B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cracr2a

Gene Alias:
Ca2+ release-activated Ca2+ (CRAC) channel regulator 2A; calcium release activated channel regulator 2A; calcium release-activated calcium channel regulator 2A; Calcium release-activated channel regulator 2A; CRAC channel regulator 2A; CRAC regulator 2A; Cracr2a; Efcab4b; EF-hand calcium binding domain 4B; EF-hand calcium-binding domain-containing protein 4B; Gm1073; Gm462; RGD1563719

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84766

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.56 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q9BSW2

Gene Symbols:
Cracr2a

Immunogen:
Recombinant protein encompassing a sequence within the center region of human EFCAB4B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585461

--


Antigen:
KLHL34

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KLHL34

Gene Alias:
FLJ34960 antibody; kelch like family member 34; kelch-like 34; kelch-like 34 (Drosophila) antibody; kelch-like family member 34; kelch-like protein 34; kelch-like protein 34 antibody; KLHL34; KLHL34 antibody; MGC125650 antibody; RGD1560439; RP11-450P7.3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
257240

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
Q8N239

Gene Symbols:
KLHL34

Immunogen:
Recombinant protein encompassing a sequence within the center region of human KLHL34.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG