PIPA585494
HIF1A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585494-Each-of-1 | In Stock | ₹ 46,844.10 |
PIPA585494 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,844.10
GST (18%): ₹ 8,431.938
Total Price: ₹ 55,276.038
Antigen
HIF1A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
HIF1A
Gene Alias
AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L homeolog; hypoxia-inducible factor 1-alpha; hypoxia-inducible factor-1 alpha; hypoxia-inducible factor1alpha; member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8; XELAEV_18039792mg; XELAEV_18041137mg; xhif1a
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100009579, 15251, 281814, 29560, 3091
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1.44 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
O35800, Q16665, Q61221, Q9XTA5
Gene Symbols
HIF1A
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human HIF1 alpha.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Human, Mouse, Rabbit, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Keep as concentrated solution
- Predicted reactivity: Mouse (90%), Rat (90%), Dog (97%), Pig (95%), Rabbit (95%), Bovine (97%)
- Positive Control: MCF-7, HeLa(500uM CoCl for 24hr), NIH-3T3 (500 uM CoCl2 treatment for 24 hr), HepG2 whole cell lysate/extract (1% O2 treatment for 24hr), 293T transfected HIF1A, HepG2 ( 200 uM CoCl2 treatment for 24 hr), HepG2 (500 uM CoCl2 treatment for 24 hr)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- HIF1-alpha (HIF1A) is a subunit of HIF1, which is a transcription factor found in mammalian cells cultured under reduced oxygen tension
- HIF-1 is a heterodimer consisting of an alpha and beta subunit, both belonging to the basic-helix-loop-helix Per-aryl hydrocarbon receptor nuclear translocator-Sim (PAS) family of transcription factors
- HIF1 functions as a transcriptional regulator of the adaptive response to hypoxia
- Under hypoxic conditions, HIF-1 activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia
- HIF1-alpha regulates hypoxia-mediated apoptosis, cell proliferation and tumor angiogenesis
- Hypoxia which induces p53 protein accumulation, directly interacts with HIF1-alpha and reduces hypoxia-induced expression of HIF1-alpha by promoting MDM2-mediated ubiquitination and proteasomal degradation under hypoxic conditions
- Recent studies suggest that induction of NOX4 by HIF1-alpha contributes to maintain ROS levels after hypoxia and hypoxia-induced proliferation
- In humans, it is located on the q arm of chromosome 14
- The C-terminal of HIF1A binds to p300
- p300/CBP-HIF complexes participate in the induction of hypoxia-responsive genes, including VEGF
- Hypoxia contributes significantly to the pathophysiology of major categories of human disease, including myocardial and cerebral ischemia, cancer, pulmonary hypertension, congenital heart disease and chronic obstructive pulmonary disease.
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Antigen: HIF1A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HIF1A
Gene Alias: AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L homeolog; hypoxia-inducible factor 1-alpha; hypoxia-inducible factor-1 alpha; hypoxia-inducible factor1alpha; member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8; XELAEV_18039792mg; XELAEV_18041137mg; xhif1a
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100009579, 15251, 281814, 29560, 3091
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: ChIP Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1.44 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: O35800, Q16665, Q61221, Q9XTA5
Gene Symbols: HIF1A
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human HIF1 alpha.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Human, Mouse, Rabbit, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HIF1A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HIF1A
Gene Alias:
AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; bHLHe78; Class E basic helix-loop-helix protein 78; HIF; hif 1; hif 1a; HIF1; HIF1 alpha; HIF-1 alpha; HIF1a; hif-1a; hif1a.L; HIF1alpha; HIF-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia inducible factor-1 alpha; hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1 alpha subunit; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L homeolog; hypoxia-inducible factor 1-alpha; hypoxia-inducible factor-1 alpha; hypoxia-inducible factor1alpha; member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8; XELAEV_18039792mg; XELAEV_18041137mg; xhif1a
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100009579, 15251, 281814, 29560, 3091
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1.44 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
O35800, Q16665, Q61221, Q9XTA5
Gene Symbols:
HIF1A
Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human HIF1 alpha.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Mouse, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Galectin 9
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Lgals9
Gene Alias: 36 kDa beta-galactoside-binding lectin; AA407335; AI194909; AI265545; ecalectin; Gal9; gal-9; galectin 9; Galectin9; galectin-9; HOM HD 21; HUAT; Lectin galactose binding soluble 9 (Galectin-9); lectin, galactose binding, soluble 5; lectin, galactose binding, soluble 9; Lectin, galactose binding, soluble 9 (Galectin-9); lectin, galactoside binding soluble 9; lectin, galactoside-binding, soluble, 9; LGALS35; Lgals5; LGALS9; LGALS9A; tumor antigen HOM-HD-21; UAT; urate transporter/channel; urate transporter/channel protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3965
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal, 0.025% ProClin 300; pH 7
Gene Accession No.: O00182
Gene Symbols: Lgals9
Immunogen: Recombinant protein encompassing a sequence within the center region of human Galectin 9.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Galectin 9
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Lgals9
Gene Alias:
36 kDa beta-galactoside-binding lectin; AA407335; AI194909; AI265545; ecalectin; Gal9; gal-9; galectin 9; Galectin9; galectin-9; HOM HD 21; HUAT; Lectin galactose binding soluble 9 (Galectin-9); lectin, galactose binding, soluble 5; lectin, galactose binding, soluble 9; Lectin, galactose binding, soluble 9 (Galectin-9); lectin, galactoside binding soluble 9; lectin, galactoside-binding, soluble, 9; LGALS35; Lgals5; LGALS9; LGALS9A; tumor antigen HOM-HD-21; UAT; urate transporter/channel; urate transporter/channel protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3965
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal, 0.025% ProClin 300; pH 7
Gene Accession No.:
O00182
Gene Symbols:
Lgals9
Immunogen:
Recombinant protein encompassing a sequence within the center region of human Galectin 9.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: IL17RB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL17RB
Gene Alias: CRL4; cytokine receptor CRL4; cytokine receptor-like 4; ecotropic viral integration site 27; EVI27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B; IL-17B receptor; IL17BR; IL-17ER; Il17rb; IL-17RB; IL17RH1; IL-17Rh1; IL-20; interleukin 17 receptor B; interleukin 17 receptor homolog 1; interleukin 17B receptor; interleukin-17 receptor B; Interleukin-17B receptor; MGC138900; MGC138901; MGC5245; UNQ2501/PRO19612; ZCYTO7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55540
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9NRM6
Gene Symbols: IL17RB
Immunogen: Recombinant protein corresponding to human IL17B Receptor.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
IL17RB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL17RB
Gene Alias:
CRL4; cytokine receptor CRL4; cytokine receptor-like 4; ecotropic viral integration site 27; EVI27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B; IL-17B receptor; IL17BR; IL-17ER; Il17rb; IL-17RB; IL17RH1; IL-17Rh1; IL-20; interleukin 17 receptor B; interleukin 17 receptor homolog 1; interleukin 17B receptor; interleukin-17 receptor B; Interleukin-17B receptor; MGC138900; MGC138901; MGC5245; UNQ2501/PRO19612; ZCYTO7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
55540
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9NRM6
Gene Symbols:
IL17RB
Immunogen:
Recombinant protein corresponding to human IL17B Receptor.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: HMGCS2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HMGCS2
Gene Alias: 1300002P16; 3-hydroxy-3-methylglutary-Coenzyme A synthase 2; 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl-CoA synthase 2; 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); 3-hydroxy-3-methylglutaryl-coenzyme A synthase; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial); hmgCoA; HMG-CoA synthase; Hmgcs1; Hmgcs2; hydroxymethylglutaryl-CoA synthase 2; hydroxymethylglutaryl-CoA synthase, mitochondrial; mHS; Mt3h3mg; testicular tissue protein Li 88
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3158
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: P54868
Gene Symbols: HMGCS2
Immunogen: Recombinant protein encompassing a sequence within the center region of human HMGCS2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HMGCS2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HMGCS2
Gene Alias:
1300002P16; 3-hydroxy-3-methylglutary-Coenzyme A synthase 2; 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl-CoA synthase 2; 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial); 3-hydroxy-3-methylglutaryl-coenzyme A synthase; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial); hmgCoA; HMG-CoA synthase; Hmgcs1; Hmgcs2; hydroxymethylglutaryl-CoA synthase 2; hydroxymethylglutaryl-CoA synthase, mitochondrial; mHS; Mt3h3mg; testicular tissue protein Li 88
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3158
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
P54868
Gene Symbols:
HMGCS2
Immunogen:
Recombinant protein encompassing a sequence within the center region of human HMGCS2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG