PIPA585640

FOXO1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585640-Each-of-1 In Stock ₹ 44,277.30

PIPA585640 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

FOXO1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FOXO1

Gene Alias

Afxh, AI876417, FKH1, FKHR, Fkhr1, forkhead box O1, forkhead box O1 a, forkhead box O1a, forkhead box O1A (rhabdomyosarcoma), forkhead box protein O1, forkhead box protein O1, LOW QUALITY PROTEIN: forkhead box protein O1, forkhead box protein O1A, Forkhead box protein O1-A, Forkhead in rhabdomyosarcoma, forkhead protein 1, forkhead protein FKHR, forkhead, Drosophila, homolog of, in rhabdomyosarcoma, fox family transcription factor FoxO1a.1, FOX01A, foxhead box protein O1-A, foxo1, FOXO1A, FoxO1a.1, member of FKHR-subclass forkhead/winged helix family, zgc:153388

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2308, 56458

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

2.13 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.

Q12778, Q9R1E0

Gene Symbols

FOXO1

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human FOXO1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Keep as concentrated solution
  • Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Chicken (90%)
  • Positive Control: Mouse testis
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • FOXO1 (FKHR, ForKHead Box 01) is a member in a subfamily of the forkhead homeotic gene family of transcription factors
  • Recent experiments have shown that FOXO1 can act as either a coactivator or a corepressor of nuclear receptor activity that is mediated through the LXXLL motif found in the carboxyl terminal region of the FKHR protein
  • Association of FOXO1 with PAX3 has been implicated in alveolar rhabdomyosarcoma
  • Recent studies link the anti-tumor activity of FOXO1, the process of autophagy and myogenic growth and differentiation
  • FOXO1 is the main target of insulin signaling that regulated the metabolic homeostasis in response to oxidative stress
  • FOXO1 binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'- TT[G/A]TTTAC-3'
  • FOXO1 is a regulator of redox balance, osteoblast numbers and controls bone mass
  • Further, FOXO1 orchestrates the endocrine function of the skeleton in regulating glucose metabolism, and suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP
  • In hepatocytes, FOXO1 promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1
  • FOXO1 is an important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1.

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Thermo Scientific

PIPA585640

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Antigen:
FOXO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FOXO1

Gene Alias:
Afxh, AI876417, FKH1, FKHR, Fkhr1, forkhead box O1, forkhead box O1 a, forkhead box O1a, forkhead box O1A (rhabdomyosarcoma), forkhead box protein O1, forkhead box protein O1, LOW QUALITY PROTEIN: forkhead box protein O1, forkhead box protein O1A, Forkhead box protein O1-A, Forkhead in rhabdomyosarcoma, forkhead protein 1, forkhead protein FKHR, forkhead, Drosophila, homolog of, in rhabdomyosarcoma, fox family transcription factor FoxO1a.1, FOX01A, foxhead box protein O1-A, foxo1, FOXO1A, FoxO1a.1, member of FKHR-subclass forkhead/winged helix family, zgc:153388

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2308, 56458

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
2.13 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
Q12778, Q9R1E0

Gene Symbols:
FOXO1

Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human FOXO1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585643

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Antigen:
GM130

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Golga2

Gene Alias:
130 kDa cis-Golgi matrix protein, AW555139, cis-Golgi matrix protein GM130, Gm130, GM130 autoantigen, GOLGA2, golgi autoantigen, golgin subfamily a, 2, Golgi matrix protein GM130, golgin A2, Golgin subfamily A member 2, Golgin subfamily A member 2, LOW QUALITY PROTEIN: golgin subfamily A member 2, golgin-95, mKIAA4150, RP11-395P17.5, SY11 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2801

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot, Western Blot

Concentration:
0.45 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
Q08379

Gene Symbols:
Golga2

Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human GM130.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585644

--


Antigen:
STAG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAG1

Gene Alias:
AU045003; cohesin subunit SA-1; DKFZp781D1416; nuclear protein stromal antigen 1; SA1; SA-1; SCC3; SCC3 homolog 1; SCC3A; STAG1; Stromal antigen 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10274

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q8WVM7

Gene Symbols:
STAG1

Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human SA1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585645

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Antigen:
Phospho-CREB (Ser133)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CREB1

Gene Alias:
2310001E10Rik, 3526402H21Rik, active transcription factor CREB, AV083133, cAMP response element binding protein 1, cAMP responsive element binding protein 1, cAMP-response element-binding protein-1, cAMP-responsive element-binding protein 1, CREB, CREB1, Creb-1, cyclic adenosine 3',5'-monophosphate response element-binding protein CREB, cyclic AMP-responsive element-binding protein 1, htCREB, MGC9284, OTTHUMP00000206661, OTTHUMP00000206662, OTTHUMP00000206667, transactivator protein, Y protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12912, 1385, 81646

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.34 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
P15337, P16220, Q01147

Gene Symbols:
CREB1

Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human CREB (phospho Ser133).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG