PIPA585714

CRY1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585714-Each-of-1 In Stock ₹ 44,705.10

PIPA585714 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CRY1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CRY1

Gene Alias

AU020726, AU021000, Cry1, cryptochrome 1 (photolyase-like), cryptochrome circadian clock 1, cryptochrome-1, PHLL1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1407

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1.19 mg/mL

Formulation

PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.

Q16526

Gene Symbols

CRY1

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CRY1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Keep as concentrated solution
  • Predicted reactivity: Rat (100%), Sheep (100%), Rhesus Monkey (100%), Bovine (100%)
  • Positive Control: HeLa
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Various biochemical, physiological and behavioral processes display circadian rhythms controlled by an internal biological clock
  • The central &quotegears&quote driving this clock appear to be composed of an autoregulatory transcription/post translation-based feedback loop
  • Cryptochrome 1 (CRY1) and 2 (CRY2) are DNA-binding flavoproteins that bear some homology to blue-light receptors and photolyases
  • In Drosophila, CRY is a photoreceptor for the circadian clock where it binds to the clock component TIM in a light-dependent fashion and blocks its function
  • Mammalian CRY1 and CRY2 function via light-independent interactions with circadian genes CLOCK and BMAL1, as well as with PER1, PER2, and TIM
  • They seem to act as light-independent components of the circadian clock and likely regulate Per1 transcriptional cycling via interactions with both the activator and its feedback inhibitors
  • Mutant mice not expressing the Cry1 or Cry2 protein display accelerated and delayed periodicity of locomotor activity, respectively
  • It appears that the combination of both proteins working together is essential to synchronize the organism to circadian phases
  • A critical balance between Cry1 and Cry2 is required for proper clock function; in complete darkness, double-mutant mice present with instantaneous arrhythmicity, indicating the absence of an internal circadian clock.

Compare Similar Items

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Thermo Scientific

PIPA585714

--


Antigen:
CRY1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CRY1

Gene Alias:
AU020726, AU021000, Cry1, cryptochrome 1 (photolyase-like), cryptochrome circadian clock 1, cryptochrome-1, PHLL1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1407

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1.19 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
Q16526

Gene Symbols:
CRY1

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CRY1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA585715

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Antigen:
PTGER1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ptger1

Gene Alias:
42kDa, EP1, EP1 prostanoid receptor, PGE receptor EP1 subtype, PGE receptor, EP1 subtype, PGE2 receptor EP1 subtype, prostaglandin E receptor 1, prostaglandin E receptor 1 (subtype EP1), prostaglandin E receptor 1 (subtype EP1), 42kD, prostaglandin E receptor 1 (subtype EP1), 42kDa, prostaglandin E receptor 1, subtype EP1, prostaglandin E receptor EP1 subtype, prostaglandin E2 receptor EP1 subtype, Prostanoid EP1 receptor, PTGER1, Ptgerep1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5731

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1.03 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
P34995

Gene Symbols:
Ptger1

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Prostaglandin E Receptor EP1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA585716

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Antigen:
Caspase 12

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CASP12

Gene Alias:
CASP12, CASP-12, CASP12P1, caspase 12, caspase 12 (gene/pseudogene), caspase 12 pseudogene 1, caspase-12, Inactive caspase-12, OTTMUSP00000045799, OTTMUSP00000045802, OTTMUSP00000045803, UNQ9415, UNQ9415/PRO34398

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100506742

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
Q6UXS9

Gene Symbols:
CASP12

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Caspase 12.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA585717

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Antigen:
Raptor

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPTOR

Gene Alias:
4932417H02Rik; KIAA1303; KOG1; Mip1; mKIAA1303; p150 target of rapamycin (TOR)-scaffold protein; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; Rap; RAPTOR; regulatory associated protein of MTOR complex 1; regulatory associated protein of MTOR, complex 1; regulatory-associated protein of mTOR; RGD1311784; RPTOR

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
287871, 57521

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.56 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q8N122

Gene Symbols:
RPTOR

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Raptor.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG