PIPA585716

Caspase 12 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585716-Each-of-1 In Stock ₹ 46,330.74

PIPA585716 - Each of 1

₹ 46,330.74

In Stock

Quantity

1

Base Price: ₹ 46,330.74

GST (18%): ₹ 8,339.533

Total Price: ₹ 54,670.273

Antigen

Caspase 12

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CASP12

Gene Alias

CASP12, CASP-12, CASP12P1, caspase 12, caspase 12 (gene/pseudogene), caspase 12 pseudogene 1, caspase-12, Inactive caspase-12, OTTMUSP00000045799, OTTMUSP00000045802, OTTMUSP00000045803, UNQ9415, UNQ9415/PRO34398

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100506742

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.13 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.

Q6UXS9

Gene Symbols

CASP12

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Caspase 12.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Keep as concentrated solution
  • Positive Control: 293T, A431, HeLa, HepG2
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Three distinct signaling pathways lead to programmed cell death (apoptosis)
  • The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved
  • The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved
  • Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion
  • Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis
  • Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including -gamma-secretase presenilin and beta-amyloid precursor protein (APP)
  • Caspase-12 mediates cytotoxicity induced by amyloid-beta
  • Caspase-12 is ubiquitously expressed in mouse tissues.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA585716

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Antigen:
Caspase 12

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CASP12

Gene Alias:
CASP12, CASP-12, CASP12P1, caspase 12, caspase 12 (gene/pseudogene), caspase 12 pseudogene 1, caspase-12, Inactive caspase-12, OTTMUSP00000045799, OTTMUSP00000045802, OTTMUSP00000045803, UNQ9415, UNQ9415/PRO34398

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100506742

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
Q6UXS9

Gene Symbols:
CASP12

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Caspase 12.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585717

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Antigen:
Raptor

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPTOR

Gene Alias:
4932417H02Rik; KIAA1303; KOG1; Mip1; mKIAA1303; p150 target of rapamycin (TOR)-scaffold protein; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; Rap; RAPTOR; regulatory associated protein of MTOR complex 1; regulatory associated protein of MTOR, complex 1; regulatory-associated protein of mTOR; RGD1311784; RPTOR

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
287871, 57521

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.56 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
Q8N122

Gene Symbols:
RPTOR

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Raptor.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585718

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Antigen:
ATG2B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATG2B

Gene Alias:
2410024A21Rik, AI047755, AI503411, ATG2 autophagy related 2 homolog B, Atg2b, autophagy related 2B, autophagy-related protein 2 homolog B, AW558123, C030004M05Rik, C14orf103, C630028L02Rik, mKIAA4067, RGD1304878

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55102

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.97 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
Q96BY7

Gene Symbols:
ATG2B

Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human ATG2B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585720

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Antigen:
Phospho-Paxillin (Ser273)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PXN

Gene Alias:
adaptor protein, AW108311, AW123232, FLJ16691, hCG_1778014, I79_001229, myocardial ischemic preconditioning associated protein 7, Pax, PAX-1, PAXI, Paxillin, paxillin a, paxillin alpha, pxn, pxna, testicular tissue protein Li 134, TGFB1I1, transforming growth factor beta 1 induced transcript 1, wu:fw71f12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19303, 5829

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1.04 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
P49023, Q8VI36

Gene Symbols:
PXN

Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human Paxillin (phospho Ser273).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG