PIPA585735

Phospho-JAK2 (Tyr1007, Tyr1008) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585735-Each-of-1 In Stock ₹ 44,705.10

PIPA585735 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-JAK2 (Tyr1007, Tyr1008)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3717

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.25 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.

O60674

Gene Symbols

JAK2

Immunogen

Carrier-protein conjugated synthetic peptide corresponding to residues around human JAK2 (phospho Tyr1007/1008).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA585740

--

Img

Thermo Scientific

PIPA585309

--

Img

Thermo Scientific

PIPA585714

--

Img

Thermo Scientific

PIPA585720

--

Img

Thermo Scientific

PIPA585694

--

Img

Thermo Scientific

PIPA585716

--

Img

Thermo Scientific

PIPA585671

--

Img

Thermo Scientific

PIPA585757

--

Description

  • Keep as concentrated solution
  • Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%)
  • Positive Control: K562
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera
  • This kinase contains the catalytic domain (JH1) of JAK2
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting JAK2 can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA585735

--


Antigen:
Phospho-JAK2 (Tyr1007, Tyr1008)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3717

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.25 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
O60674

Gene Symbols:
JAK2

Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human JAK2 (phospho Tyr1007/1008).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585736

--


Antigen:
Phospho-mTOR (Ser2448)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MTOR

Gene Alias:
2610315D21Rik, AI327068, angiopoietin-like factor CDT6, FK506 binding protein 12-rapamycin associated protein 1, FK506 binding protein 12-rapamycin associated protein 2, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, FKBP12-rapamycin complex-associated protein 1, FKBP-rapamycin associated protein, FKBP-rapamycin associated protein (FRAP), FKBP-rapamycin-associated protein FRAP, flat, FRAP, FRAP1, FRAP2, Mammalian target of rapamycin, mechanistic target of rapamycin, mechanistic target of rapamycin (serine/threonine kinase), mechanistic target of rapamycin kinase, Mtor, m-TOR, mTORC1, Raft1, Rapamycin and FKBP12 target 1, rapamycin and FKBP12 target-1 protein, rapamycin associated protein FRAP2, rapamycin target protein 1, RAPT1, serine/threonine-protein kinase mTOR, SKS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2475, 56717

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
P42345, Q9JLN9

Gene Symbols:
MTOR

Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human mTOR (phospho Ser2448).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585740

--


Antigen:
Phospho-Phospholamban (Ser16)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLN

Gene Alias:
cardiac CMH18; Cardiac phospholamban; CMD1P; CMH18; phospholamban; Plb; Plm; PLN; unnamed protein product

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18821, 5350

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.97 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P26678, P61014

Gene Symbols:
PLN

Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human Phospholamban (phospho Ser16).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585743

--


Antigen:
LC3A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP1LC3A

Gene Alias:
1010001H21Rik, 4922501H04Rik, ATG8E, Autophagy-related protein LC3 A, autophagy-related ubiquitin-like modifier LC3 A, LC3, LC3a, MAP1 light chain 3-like protein 1, MAP1A/1B light chain 3 A, MAP1A/MAP1B LC3 A, MAP1A/MAP1B light chain 3 A, MAP1ALC3, MAP1BLC3, map1lc3a, microtubule associated protein 1 light chain 3 alpha, Microtubule-asso, microtubule-associated protein 1 light chain 3 alpha, microtubule-associated protein 1-light chain 3A, microtubule-associated proteins 1A/1B light chain 3, microtubule-associated proteins 1A/1B light chain 3A, MLP3A, RP11-346K17.1, similar to microtubule-associated protein 1 light chain 3 alpha, zgc:77094

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
66734, 84557

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.2 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
Q91VR7, Q9H492

Gene Symbols:
MAP1LC3A

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human LC3A.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG