PIPA585932
SCN10A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585932-Each-of-1 | In Stock | ₹ 43,592.82 |
PIPA585932 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,592.82
GST (18%): ₹ 7,846.708
Total Price: ₹ 51,439.528
Antigen
SCN10A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Scn10a
Gene Alias
FEPS2; hPN3; mPN3; Na(V)1.8; Nav1.8; peripheral nerve sodium channel 3; PN3; Scn10a; Sensory neuron sodium channel; SNS; Sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; sodium channel type X alpha polypeptide; sodium channel voltage-gated type X alpha polypeptide; sodium channel, voltage gated, type X alpha subunit; sodium channel, voltage-gated, type 10, alpha polypeptide; sodium channel, voltage-gated, type X, alpha; sodium channel, voltage-gated, type X, alpha polypeptide; sodium channel, voltage-gated, type X, alpha subunit; sodium voltage-gated channel alpha subunit 10; voltage gated sodium channel; voltage-gated sodium channel subunit alpha Nav1.8
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
20264, 29571
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q62968, Q6QIY3
Gene Symbols
Scn10a
Immunogen
Synthetic peptide within rat NaV18 aa 1,907-1,956
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Rabbit Polyclonal Antibody Scn10a is a tetrodotoxin-resistant voltage-gated sodium channel alpha subunit
- Epithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels
- Scn10a mediates the voltage-dependent sodium ion permeability of excitable membranes
- Assuming opened or closed conformations in response to the voltage difference across the membrane, Scn10a forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient
- Scn10a also plays a role in neuropathic pain mechanisms
- Structurally, members of Deg/ENaC superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region
- There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein
- ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance
- ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure
- ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel
- Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddels syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1)
- Diseases associated with SCN10A include Episodic Pain Syndrome, Familial, 2 and Sodium Channelopathy-Related Small Fiber Neuropathy.
Compare Similar Items
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Antigen: SCN10A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Scn10a
Gene Alias: FEPS2; hPN3; mPN3; Na(V)1.8; Nav1.8; peripheral nerve sodium channel 3; PN3; Scn10a; Sensory neuron sodium channel; SNS; Sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; sodium channel type X alpha polypeptide; sodium channel voltage-gated type X alpha polypeptide; sodium channel, voltage gated, type X alpha subunit; sodium channel, voltage-gated, type 10, alpha polypeptide; sodium channel, voltage-gated, type X, alpha; sodium channel, voltage-gated, type X, alpha polypeptide; sodium channel, voltage-gated, type X, alpha subunit; sodium voltage-gated channel alpha subunit 10; voltage gated sodium channel; voltage-gated sodium channel subunit alpha Nav1.8
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 20264, 29571
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q62968, Q6QIY3
Gene Symbols: Scn10a
Immunogen: Synthetic peptide within rat NaV18 aa 1,907-1,956
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SCN10A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Scn10a
Gene Alias:
FEPS2; hPN3; mPN3; Na(V)1.8; Nav1.8; peripheral nerve sodium channel 3; PN3; Scn10a; Sensory neuron sodium channel; SNS; Sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; sodium channel type X alpha polypeptide; sodium channel voltage-gated type X alpha polypeptide; sodium channel, voltage gated, type X alpha subunit; sodium channel, voltage-gated, type 10, alpha polypeptide; sodium channel, voltage-gated, type X, alpha; sodium channel, voltage-gated, type X, alpha polypeptide; sodium channel, voltage-gated, type X, alpha subunit; sodium voltage-gated channel alpha subunit 10; voltage gated sodium channel; voltage-gated sodium channel subunit alpha Nav1.8
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
20264, 29571
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q62968, Q6QIY3
Gene Symbols:
Scn10a
Immunogen:
Synthetic peptide within rat NaV18 aa 1,907-1,956
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ZIP12
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SLC39A12
Gene Alias: AW046938; bA570F3.1; Gm731; LIV-1 subfamily of ZIP zinc transporter 8; LZT-Hs8; Slc39a12; solute carrier family 39 (metal ion transporter), member 12; solute carrier family 39 (zinc transporter), member 12; solute carrier family 39 member 12; Zinc transporter ZIP12; Zip12; ZIP-12; Zrt- and Irt-like protein 12
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 221074, 277468, 291328
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q504Y0, Q5FWH7
Gene Symbols: SLC39A12
Immunogen: Synthetic peptide within human zip12 aa 685-691 (extracellular).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ZIP12
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SLC39A12
Gene Alias:
AW046938; bA570F3.1; Gm731; LIV-1 subfamily of ZIP zinc transporter 8; LZT-Hs8; Slc39a12; solute carrier family 39 (metal ion transporter), member 12; solute carrier family 39 (zinc transporter), member 12; solute carrier family 39 member 12; Zinc transporter ZIP12; Zip12; ZIP-12; Zrt- and Irt-like protein 12
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
221074, 277468, 291328
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q504Y0, Q5FWH7
Gene Symbols:
SLC39A12
Immunogen:
Synthetic peptide within human zip12 aa 685-691 (extracellular).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ATF6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ATF6
Gene Alias: 9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; Atf6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; Atf6b; ATF6beta; ATF6-beta; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; Crebl1; Creb-related protein; CREB-RP; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1388, 22926, 304962, 406169
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: G3V909, P18850, Q99941
Gene Symbols: ATF6, ATF6B
Immunogen: Recombinant protein within Human ATF6 aa 168-392
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ATF6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ATF6
Gene Alias:
9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; Atf6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; Atf6b; ATF6beta; ATF6-beta; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; Crebl1; Creb-related protein; CREB-RP; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1388, 22926, 304962, 406169
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
G3V909, P18850, Q99941
Gene Symbols:
ATF6, ATF6B
Immunogen:
Recombinant protein within Human ATF6 aa 168-392
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CD71 (Transferrin Receptor)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TFRC
Gene Alias: 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 22042, 7037
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P02786, Q62351
Gene Symbols: TFRC
Immunogen: Recombinant protein within Human CD71 aa 463-750
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CD71 (Transferrin Receptor)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TFRC
Gene Alias:
2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
22042, 7037
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P02786, Q62351
Gene Symbols:
TFRC
Immunogen:
Recombinant protein within Human CD71 aa 463-750
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG