PIPA585948
ROCK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585948-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA585948 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
ROCK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Rock1
Gene Alias
1110055K06Rik; Ac2-154; Liver regeneration-related protein LRRG199; MGC131603; MGC43611; p150 RhoA-binding kinase ROK beta; p160 ROCK-1; p160ROCK; p160-ROCK; PRO0435; Renal carcinoma antigen NY-REN-35; Rho associated coiled-coil containing protein kinase 1; Rho kinase; Rho-associated coiled-coil containing protein kinase 1; Rho-associated coiled-coil forming kinase 1; Rho-associated kinase beta; rho-associated protein kinase 1; Rho-associated, coiled-coil containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; Rho-associated, coiled-coil-containing protein kinase I; ROCK1; ROCK-I
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19877, 6093
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P70335, Q13464
Gene Symbols
Rock1
Immunogen
Synthetic peptide within residues of ROCK1 aa 1,305-1,354
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Rabbit Polyclonal Antibody ROCK1 is a serine/threonine kinase that regulates cell differentiation and migration
- The Rho/ROCK pathway is involved in the progression of various human cancers
- ROCK1 has been found to be a new Caspase-3 substrate
- ROCK, one of the effectors of the small GTPase Rho, has recently been shown to contribute significantly to myosin light chain (MLC) activation through two pathways: direct phosphorylation of MLC and phosphorylation of MLC phosphatase, leading to its inhibition
- The increase in cellular contractility that is necessary for apoptotic membrane blebbing implies sustained augmentation of MLC phosphorylation
- ROCK-1 consists of an amino-terminal kinase domain and an inhibitory cysteine/histidine-rich C-terminal domain that is located within a pleckstrin-homology region
- They are joined by a variable region that contains the Rho-binding domain
- During apoptosis, ROCK-I is cleaved by caspase-3 at a conserved DETD1113/G sequence and its carboxy-terminal inhibitory domain is removed, resulting in deregulated and constitutive kinase activity
- The caspase-3-mediated cleavage and activation of ROCK I induces phosphorylation of MLC and membrane blebbing, one of the first events in the execution phase of apoptosis.
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Antigen: ROCK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Rock1
Gene Alias: 1110055K06Rik; Ac2-154; Liver regeneration-related protein LRRG199; MGC131603; MGC43611; p150 RhoA-binding kinase ROK beta; p160 ROCK-1; p160ROCK; p160-ROCK; PRO0435; Renal carcinoma antigen NY-REN-35; Rho associated coiled-coil containing protein kinase 1; Rho kinase; Rho-associated coiled-coil containing protein kinase 1; Rho-associated coiled-coil forming kinase 1; Rho-associated kinase beta; rho-associated protein kinase 1; Rho-associated, coiled-coil containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; Rho-associated, coiled-coil-containing protein kinase I; ROCK1; ROCK-I
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19877, 6093
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P70335, Q13464
Gene Symbols: Rock1
Immunogen: Synthetic peptide within residues of ROCK1 aa 1,305-1,354
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ROCK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Rock1
Gene Alias:
1110055K06Rik; Ac2-154; Liver regeneration-related protein LRRG199; MGC131603; MGC43611; p150 RhoA-binding kinase ROK beta; p160 ROCK-1; p160ROCK; p160-ROCK; PRO0435; Renal carcinoma antigen NY-REN-35; Rho associated coiled-coil containing protein kinase 1; Rho kinase; Rho-associated coiled-coil containing protein kinase 1; Rho-associated coiled-coil forming kinase 1; Rho-associated kinase beta; rho-associated protein kinase 1; Rho-associated, coiled-coil containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; Rho-associated, coiled-coil-containing protein kinase I; ROCK1; ROCK-I
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19877, 6093
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P70335, Q13464
Gene Symbols:
Rock1
Immunogen:
Synthetic peptide within residues of ROCK1 aa 1,305-1,354
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: GAP43
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GAP43
Gene Alias: Axonal membrane protein GAP-43; B-50; Basp2; brain abundant, membrane attached signal protein 2; calmodulin-binding protein P-57; Gap43; GAP-43; growth accentuating protein 43; growth associated protein 43; growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; PP46; Protein F1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14432, 2596, 29423
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P06837, P07936, P17677
Gene Symbols: GAP43
Immunogen: Synthetic peptide within mouse GAP43 aa 178-227
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
GAP43
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GAP43
Gene Alias:
Axonal membrane protein GAP-43; B-50; Basp2; brain abundant, membrane attached signal protein 2; calmodulin-binding protein P-57; Gap43; GAP-43; growth accentuating protein 43; growth associated protein 43; growth-associated protein 43; MGC156666; nerve growth-related peptide GAP43; neural phosphoprotein B-50; Neuromodulin; neuron growth-associated protein 43; neuron protein F1; PP46; Protein F1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14432, 2596, 29423
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P06837, P07936, P17677
Gene Symbols:
GAP43
Immunogen:
Synthetic peptide within mouse GAP43 aa 178-227
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: c-Met
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MET
Gene Alias: AI838057; AUTS9; bHLHe59; CG1705; CG1705-PA; CG1705-PB; cmet; c-met; c-met proto-oncogene; c-Met receptor tyrosine kinase; c-Met/HGF receptor; D249; DFNB97; Dmel\CG1705; Dmel_CG1705; DmMet; EC 2.7.10.1; Hepatocyte growth factor receptor; HGF; HGF receptor; HGF receptor c-Met; HGF/SF receptor; HGFR; HGF-SF receptor; juvenile hormone resistance; met; met proto-oncogene; met proto-oncogene (hepatocyte growth factor receptor); met proto-oncogene tyrosine kinase; MET proto-oncogene, receptor tyrosine kinase; Met/Met1; Met; protein tyrosin kinase; methoprene tolerant; Methoprene-tolerant; Methoprene-tolerant protein; Met-PA; Met-PB; Mett; oncogene MET; Par4; Proto-oncogene c-Met; RCCP2; resistance (1) juvenile H; resistance to juvenile hormone; Rst(1)JH; sc MET; scatter factor receptor; SF receptor; soluble c met; tyrosine-protein kinase Met
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17295, 24553, 4233
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P08581, P16056, P97523
Gene Symbols: MET
Immunogen: Synthetic peptide within mouse cMet aa 641-690
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
c-Met
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MET
Gene Alias:
AI838057; AUTS9; bHLHe59; CG1705; CG1705-PA; CG1705-PB; cmet; c-met; c-met proto-oncogene; c-Met receptor tyrosine kinase; c-Met/HGF receptor; D249; DFNB97; Dmel\CG1705; Dmel_CG1705; DmMet; EC 2.7.10.1; Hepatocyte growth factor receptor; HGF; HGF receptor; HGF receptor c-Met; HGF/SF receptor; HGFR; HGF-SF receptor; juvenile hormone resistance; met; met proto-oncogene; met proto-oncogene (hepatocyte growth factor receptor); met proto-oncogene tyrosine kinase; MET proto-oncogene, receptor tyrosine kinase; Met/Met1; Met; protein tyrosin kinase; methoprene tolerant; Methoprene-tolerant; Methoprene-tolerant protein; Met-PA; Met-PB; Mett; oncogene MET; Par4; Proto-oncogene c-Met; RCCP2; resistance (1) juvenile H; resistance to juvenile hormone; Rst(1)JH; sc MET; scatter factor receptor; SF receptor; soluble c met; tyrosine-protein kinase Met
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17295, 24553, 4233
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P08581, P16056, P97523
Gene Symbols:
MET
Immunogen:
Synthetic peptide within mouse cMet aa 641-690
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: NALP5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NLRP5
Gene Alias: CLR19.8; MATER; Mater protein; Mater protein homolog; maternal antigen that embryos require; NACHT, leucine rich repeat and PYD containing 5; NACHT, LRR and PYD domains-containing protein 5; Nalp5; NLR family pyrin domain containing 5; NLR family, pyrin domain containing 5; NLRP5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5; Ooplasm-specific protein 1; OP1; PAN11; PYPAF8
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 126206, 23968
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P59047, Q9R1M5
Gene Symbols: NLRP5
Immunogen: Synthetic peptide within mouse MATER aa 1,114-1,163
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
NALP5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NLRP5
Gene Alias:
CLR19.8; MATER; Mater protein; Mater protein homolog; maternal antigen that embryos require; NACHT, leucine rich repeat and PYD containing 5; NACHT, LRR and PYD domains-containing protein 5; Nalp5; NLR family pyrin domain containing 5; NLR family, pyrin domain containing 5; NLRP5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 5; Ooplasm-specific protein 1; OP1; PAN11; PYPAF8
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
126206, 23968
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P59047, Q9R1M5
Gene Symbols:
NLRP5
Immunogen:
Synthetic peptide within mouse MATER aa 1,114-1,163
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG