PIPA586583
ROCK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586583-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586583 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
ROCK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Rock1
Gene Alias
1110055K06Rik, Ac2-154, Liver regeneration-related protein LRRG199, MGC131603, MGC43611, p150 RhoA-binding kinase ROK beta, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho associated coiled-coil containing protein kinase 1, Rho kinase, Rho-associated coiled-coil containing protein kinase 1, Rho-associated coiled-coil forming kinase 1, Rho-associated kinase beta, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, rho-associated, coiled-coil-containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase I, ROCK1, ROCK-I
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19877, 6093, 81762
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P70335, Q13464, Q63644
Gene Symbols
Rock1
Immunogen
Synthetic peptide, corresponding to amino acids 280-331 of Human Rock-1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- ROCK1 is a serine/threonine kinase that regulates cell differentiation and migration
- The Rho/ROCK pathway is involved in the progression of various human cancers
- ROCK1 has been found to be a new Caspase-3 substrate
- ROCK, one of the effectors of the small GTPase Rho, has recently been shown to contribute significantly to myosin light chain (MLC) activation through two pathways: direct phosphorylation of MLC and phosphorylation of MLC phosphatase, leading to its inhibition
- The increase in cellular contractility that is necessary for apoptotic membrane blebbing implies sustained augmentation of MLC phosphorylation
- ROCK-1 consists of an amino-terminal kinase domain and an inhibitory cysteine/histidine-rich C-terminal domain that is located within a pleckstrin-homology region
- They are joined by a variable region that contains the Rho-binding domain
- During apoptosis, ROCK-I is cleaved by caspase-3 at a conserved DETD1113/G sequence and its carboxy-terminal inhibitory domain is removed, resulting in deregulated and constitutive kinase activity
- The caspase-3-mediated cleavage and activation of ROCK I induces phosphorylation of MLC and membrane blebbing, one of the first events in the execution phase of apoptosis.
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Antigen: ROCK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Rock1
Gene Alias: 1110055K06Rik, Ac2-154, Liver regeneration-related protein LRRG199, MGC131603, MGC43611, p150 RhoA-binding kinase ROK beta, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho associated coiled-coil containing protein kinase 1, Rho kinase, Rho-associated coiled-coil containing protein kinase 1, Rho-associated coiled-coil forming kinase 1, Rho-associated kinase beta, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, rho-associated, coiled-coil-containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase I, ROCK1, ROCK-I
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19877, 6093, 81762
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P70335, Q13464, Q63644
Gene Symbols: Rock1
Immunogen: Synthetic peptide, corresponding to amino acids 280-331 of Human Rock-1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ROCK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Rock1
Gene Alias:
1110055K06Rik, Ac2-154, Liver regeneration-related protein LRRG199, MGC131603, MGC43611, p150 RhoA-binding kinase ROK beta, p160 ROCK-1, p160ROCK, p160-ROCK, PRO0435, Renal carcinoma antigen NY-REN-35, Rho associated coiled-coil containing protein kinase 1, Rho kinase, Rho-associated coiled-coil containing protein kinase 1, Rho-associated coiled-coil forming kinase 1, Rho-associated kinase beta, rho-associated protein kinase 1, Rho-associated, coiled-coil containing protein kinase 1, rho-associated, coiled-coil-containing protein kinase 1, Rho-associated, coiled-coil-containing protein kinase I, ROCK1, ROCK-I
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19877, 6093, 81762
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P70335, Q13464, Q63644
Gene Symbols:
Rock1
Immunogen:
Synthetic peptide, corresponding to amino acids 280-331 of Human Rock-1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CCL3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ccl3
Gene Alias: AI323804, C-C motif chemokine 3, C-C motif chemokine ligand 3, CCL3, chemokine (C-C motif) ligand 3, G0/G1 switch regulatory protein 19-1, G0S19-1, Heparin-binding chemotaxis protein, H-MIP-1-alpha, L2G25B, LD78ALPHA, LD78-alpha, LD78-alpha(4-69), Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3), macrophage inflammatory protein 1-alpha, macrophage inflammatory protein-1alpha, MIP1 (a), mip1 alpha, MIP-1 alpha, MIP1-(a), MIP1A, MIP-1a, MIP-1alpha, MIP-1-alpha, MIP1-alpha, MIP-1-alpha(4-69), PAT 464.1, RP23-320E6.7, Scya3, SIS-alpha, SIS-beta, small inducible cytokine A3, small inducible cytokine A3 (homologous to mouse Mip-1a), small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein, TY-5
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20302, 25542, 6348
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P10147, P10855, P50229
Gene Symbols: Ccl3
Immunogen: Synthetic peptide, corresponding to amino acids 41-90 of Human MIP-1alpha.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CCL3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ccl3
Gene Alias:
AI323804, C-C motif chemokine 3, C-C motif chemokine ligand 3, CCL3, chemokine (C-C motif) ligand 3, G0/G1 switch regulatory protein 19-1, G0S19-1, Heparin-binding chemotaxis protein, H-MIP-1-alpha, L2G25B, LD78ALPHA, LD78-alpha, LD78-alpha(4-69), Macrophage inflammatory protein 1 alpha (Small inducible cytokine A3), macrophage inflammatory protein 1-alpha, macrophage inflammatory protein-1alpha, MIP1 (a), mip1 alpha, MIP-1 alpha, MIP1-(a), MIP1A, MIP-1a, MIP-1alpha, MIP-1-alpha, MIP1-alpha, MIP-1-alpha(4-69), PAT 464.1, RP23-320E6.7, Scya3, SIS-alpha, SIS-beta, small inducible cytokine A3, small inducible cytokine A3 (homologous to mouse Mip-1a), small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein, TY-5
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20302, 25542, 6348
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P10147, P10855, P50229
Gene Symbols:
Ccl3
Immunogen:
Synthetic peptide, corresponding to amino acids 41-90 of Human MIP-1alpha.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: BNIP3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BNIP3
Gene Alias: BCL2 interacting protein 3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BCL2/adenovirus E1B 19 kDa-interacting protein 1, NIP3, BCL2/adenovirus E1B 19 kDa-interacting protein 3, BCL2/adenovirus E1B 19kDa interacting protein 3, BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3, BCL2/adenovirus E1B interacting protein 1, NIP3, BCL2/adenovirus E1B interacting protein 3, Bnip3, NIP3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12176, 664, 84480
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: O55003, Q12983
Gene Symbols: BNIP3
Immunogen: Synthetic peptide, corresponding to amino acids 70-120 of Human BNIP-3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
BNIP3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BNIP3
Gene Alias:
BCL2 interacting protein 3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, BCL2/adenovirus E1B 19 kDa-interacting protein 1, NIP3, BCL2/adenovirus E1B 19 kDa-interacting protein 3, BCL2/adenovirus E1B 19kDa interacting protein 3, BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3, BCL2/adenovirus E1B interacting protein 1, NIP3, BCL2/adenovirus E1B interacting protein 3, Bnip3, NIP3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12176, 664, 84480
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
O55003, Q12983
Gene Symbols:
BNIP3
Immunogen:
Synthetic peptide, corresponding to amino acids 70-120 of Human BNIP-3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Lamin B1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Lmnb1
Gene Alias: 0710005A05Rik, ADLD, C-flanking peptide of NPY, CPON, fc06g01, I79_003938, lamin B1, lamin B1 L homeolog, lamin B1 protein, lamin-b, lamin-B1, Lamin-L(I), LMN, LMN2, LMNB, LMNB1, lmnb1 protein, lmnb1.L, MGC111419, Neuropeptide tyrosine, Neuropeptide Y, NPY, NPY02, prepro-neuropeptide Y, pro-neuropeptide Y, PYY4, RATNPY, RATNPY02, unnamed protein product, wu:fc06g01, XELAEV_18007951mg
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116685, 16906, 4001
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P14733, P20700, P70615
Gene Symbols: Lmnb1
Immunogen: Synthetic peptide, corresponding to amino acids 50-100 of Human Lamin B1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Lamin B1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Lmnb1
Gene Alias:
0710005A05Rik, ADLD, C-flanking peptide of NPY, CPON, fc06g01, I79_003938, lamin B1, lamin B1 L homeolog, lamin B1 protein, lamin-b, lamin-B1, Lamin-L(I), LMN, LMN2, LMNB, LMNB1, lmnb1 protein, lmnb1.L, MGC111419, Neuropeptide tyrosine, Neuropeptide Y, NPY, NPY02, prepro-neuropeptide Y, pro-neuropeptide Y, PYY4, RATNPY, RATNPY02, unnamed protein product, wu:fc06g01, XELAEV_18007951mg
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116685, 16906, 4001
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P14733, P20700, P70615
Gene Symbols:
Lmnb1
Immunogen:
Synthetic peptide, corresponding to amino acids 50-100 of Human Lamin B1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG