PIPA586013

TSC2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586013-Each-of-1 In Stock ₹ 43,592.82

PIPA586013 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

TSC2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TSC2

Gene Alias

LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22084, 7249

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry

Concentration

1 mg/mL

Formulation

PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P49815, Q61037

Gene Symbols

TSC2

Immunogen

Synthetic peptide within Human TSC2 aa 1,758-1,807

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Rabbit Polyclonal Antibody TSC2 (Tuberin, Tuberous sclerosis complex, TSC Complex Subunit 2), is implicated as a tumor suppressor and may function in vesicular transport, play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin
  • Phosphorylation of tuberin on Ser 939 and Thr 1462 regulates its interaction with hamartin, and is stimulated by various growth factors through the phosphoinositide 3-kinase/Akt pathway
  • TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • Interaction between TSC1 and TSC2 may facilitate vesicular docking
  • TSC2 specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth
  • Mutations in TSC2 lead to constitutive activation of RAP1A in tumors and are involved in diseases such as lymphangioleiomyomatosis and TSC2 angiomyolipoma
  • Alternative splicing results in transcript variants of three different isoforms of TSC2.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA586013

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Antigen:
TSC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSC2

Gene Alias:
LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22084, 7249

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P49815, Q61037

Gene Symbols:
TSC2

Immunogen:
Synthetic peptide within Human TSC2 aa 1,758-1,807

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA586015

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Antigen:
PYGO2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PYGO2

Gene Alias:
1190004M21Rik; mpygo2; PP7910; PYGO2; pygopus 2; pygopus family PHD finger 2; pygopus homolog 2; RGD1308535

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
68911, 90780

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9BRQ0

Gene Symbols:
PYGO2

Immunogen:
Synthetic peptide within Human Pygopus aa 31-80

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA586017

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Antigen:
MSH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Msh2

Gene Alias:
AI788990; COCA1; DNA mismatch repair protein MSH2; FCC1; hMSH2; HNPCC; HNPCC1; LCFS2; mismatch repair ATPase MSH2; mismatch repair protein; MSH2; Msh2p; mutS homolog 2; mutS homolog 2 (E. coli); mutS homolog 2, colon cancer, nonpolyposis type 1; mutS protein homolog 2; O0935; PMS5; YOL090W

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17685, 4436, 81709

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P43246, P43247, P54275

Gene Symbols:
Msh2

Immunogen:
Synthetic peptide within Human MSH2 aa 21-70

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA586019

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Antigen:
PRDX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRDX2

Gene Alias:
AL022839; Band-8; Calpromotin; epididymis secretory sperm binding protein Li 2a; HEL-S-2a; HGNC:9353; MGC4104; Natural killer cell-enhancing factor B; NkefB; NKEF-B; peroxiredoxin 2; peroxiredoxin-2; Prdx2; protector protein; PRP; Prx II-1; PRX2; PRXII; PTX1; Tdpx1; TDX1; thiol specific antioxidant protein; thiol-specific antioxidant 1; thiol-specific antioxidant protein; thioredoxin dependent peroxide reductase 1; thioredoxin peroxidase 1; thioredoxin reductase; thioredoxin-dependent peroxide reductase 1; Torin; TPx; TPX1; TPx-B; TR; Trx dependent peroxide reductase 1; TSA

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21672, 29338, 7001

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P32119, P35704, Q61171

Gene Symbols:
PRDX2

Immunogen:
Synthetic peptide within Human Peroxiredoxin 2 aa 149-198

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG