PIPA586305

TSC2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586305-Each-of-1 In Stock ₹ 44,191.74

PIPA586305 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

TSC2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TSC2

Gene Alias

LAM, Nafld, OTTHUMP00000198394, PPP1R160, protein phosphatase 1, regulatory subunit 160, Rc, renal carcinoma, Tcs2, Tsc2, TSC4, Tuberin, tuberous sclerosis 2, tuberous sclerosis 2 homolog protein, tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein homolog

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22084, 24855, 7249

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

P49815, P49816, Q61037

Gene Symbols

TSC2

Immunogen

Synthetic peptide, corresponding to amino acids 900-950 of Human Tuberin.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • TSC2 (Tuberin, Tuberous sclerosis complex, TSC Complex Subunit 2), is implicated as a tumor suppressor and may function in vesicular transport, play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin
  • Phosphorylation of tuberin on Ser 939 and Thr 1462 regulates its interaction with hamartin, and is stimulated by various growth factors through the phosphoinositide 3-kinase/Akt pathway
  • TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • Interaction between TSC1 and TSC2 may facilitate vesicular docking
  • TSC2 specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth
  • Mutations in TSC2 lead to constitutive activation of RAP1A in tumors and are involved in diseases such as lymphangioleiomyomatosis and TSC2 angiomyolipoma
  • Alternative splicing results in transcript variants of three different isoforms of TSC2.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586305

--


Antigen:
TSC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSC2

Gene Alias:
LAM, Nafld, OTTHUMP00000198394, PPP1R160, protein phosphatase 1, regulatory subunit 160, Rc, renal carcinoma, Tcs2, Tsc2, TSC4, Tuberin, tuberous sclerosis 2, tuberous sclerosis 2 homolog protein, tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22084, 24855, 7249

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P49815, P49816, Q61037

Gene Symbols:
TSC2

Immunogen:
Synthetic peptide, corresponding to amino acids 900-950 of Human Tuberin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586306

--


Antigen:
TSC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSC2

Gene Alias:
LAM, Nafld, OTTHUMP00000198394, PPP1R160, protein phosphatase 1, regulatory subunit 160, Rc, renal carcinoma, Tcs2, Tsc2, TSC4, Tuberin, tuberous sclerosis 2, tuberous sclerosis 2 homolog protein, tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24855, 7249

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P49815, P49816

Gene Symbols:
TSC2

Immunogen:
Synthetic peptide, corresponding to amino acids 1400-1500 of Human Tuberin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA586307

--


Antigen:
XIAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
XIAP

Gene Alias:
1110015C02Rik, Aipa, Api3, apoptosis inhibitor protein 3, baculoviral IAP repeat-containing 4, baculoviral IAP repeat-containing protein 4, BIR4, Birc4, E3 ubiquitin-protein ligase XIAP, hIAP3, hIAP-3, HILP, IAP homolog A, IAP3, IAP-3, IAP-like protein, ILP, ILP1, ILP-1, Inhibitor of apoptosis protein 3, MIHA, riap3, RIAP-3, RING-type E3 ubiquitin transferase XIAP, RP1-315G1.5, XIAP, X-linked IAP, X-linked inhibitor of apoptosis, X-linked inhibitor of apoptosis protein, X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase, XLP2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11798, 331, 63879

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P98170, Q60989, Q9R0I6

Gene Symbols:
XIAP

Immunogen:
Synthetic peptide, corresponding to amino acids 50-100 of Human XIAP.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA586308

--


Antigen:
Zap-70

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZAP70

Gene Alias:
70 kDa zeta-associated protein, 70 kDa zeta-chain associated protein, ADMIO2, EC 2.7.10.2, FLJ17670, FLJ17679, I79_004087, IMD48, kinase ZAP70, mrtle, mur, Selective T cell defect, Srk, STCD, STD, syk-related protein tyrosine kinase, syk-related tyrosine kinase, Tyrosine-protein kinase ZAP-70, Tyrosine-protein kinase ZAP-70;TZK, TZK, ZA70, Zap70, ZAP-70, Zeta chain associated protein kinase 70kDa, zeta chain of T cell receptor associated protein kinase, zeta chain of T cell receptor associated protein kinase 70, zeta chain of T cell receptor associated protein kinase 70kDa, zeta-chain (TCR) associated protein kinase, zeta-chain (TCR) associated protein kinase 70, zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain associated protein kinase 70kDa, zeta-chain associated protein kinase, 70kD

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
301348, 7535

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P43403

Gene Symbols:
ZAP70

Immunogen:
Synthetic peptide, corresponding to amino acids 250-300 of Human ZAP70.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG