PIPA586031
SHP-1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586031-Each-of-1 | In Stock | ₹ 43,592.82 |
PIPA586031 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,592.82
GST (18%): ₹ 7,846.708
Total Price: ₹ 51,439.528
Antigen
SHP-1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTPN6
Gene Alias
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
116689, 15170, 5777
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P29350, P29351, P81718
Gene Symbols
PTPN6
Immunogen
Recombinant protein within C-terminal Human SHP-1 aa 550-595
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Rabbit Polyclonal Antibody SHP-1 (PTPN6) is a non-receptor protein tyrosine phosphatase that is expressed primarily in hematopoietic cells
- The enzyme is composed of two SH2 domains, a tyrosine phosphatase catalytic domain, and a carboxy-terminal regulatory domain
- SHP-1 removes phosphates from target proteins to downregulate several tyrosine kinase-regulated pathways
- In hematopoietic cells, the amino-terminal SH2 domain of SHP-1 binds to tyrosine phosphorylated erythropoietin receptors (EpoR) to negatively regulate hematopoietic growth
- Overexpression of SHP-1 in epithelial cells results in dephosphorylation of the Ros receptor tyrosine kinase and subsequent downregulation of Ros-dependent cell proliferation and transformation
- Following ligand binding in myeloid cells, SHP-1 associates with the IL-3R beta chain and downregulates IL-3-induced tyrosine phosphorylation and cell proliferation.
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Antigen: SHP-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTPN6
Gene Alias: 70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 116689, 15170, 5777
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: P29350, P29351, P81718
Gene Symbols: PTPN6
Immunogen: Recombinant protein within C-terminal Human SHP-1 aa 550-595
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SHP-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTPN6
Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
116689, 15170, 5777
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P29350, P29351, P81718
Gene Symbols:
PTPN6
Immunogen:
Recombinant protein within C-terminal Human SHP-1 aa 550-595
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MYLK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYLK
Gene Alias: 155 kda myosin light chain kinase homolog; 9530072E15Rik; A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA; The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene.; A930019C19Rik; AAT7; AW489456; kinase related protein; kinase-related protein; KRP; KRP/Telokin; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; mylk; MYLK1; myosin light chain kinase; myosin light chain kinase, smooth muscle; Myosin light chain kinase, smooth muscle, deglutamylated form; myosin, light polypeptide kinase; nmMlck; smMLCK; smooth muscle myosin light chain kinase; smooth muscle myosin light chain kinase (61-kDa active fragment); smooth muscle myosin light chain kinase precursor (EC 2.7.2.37); telokin; unnamed protein product
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 107589, 4638
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q15746, Q6PDN3
Gene Symbols: MYLK
Immunogen: Recombinant protein with Human MYLK aa 230-470
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MYLK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MYLK
Gene Alias:
155 kda myosin light chain kinase homolog; 9530072E15Rik; A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA; The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene.; A930019C19Rik; AAT7; AW489456; kinase related protein; kinase-related protein; KRP; KRP/Telokin; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; mylk; MYLK1; myosin light chain kinase; myosin light chain kinase, smooth muscle; Myosin light chain kinase, smooth muscle, deglutamylated form; myosin, light polypeptide kinase; nmMlck; smMLCK; smooth muscle myosin light chain kinase; smooth muscle myosin light chain kinase (61-kDa active fragment); smooth muscle myosin light chain kinase precursor (EC 2.7.2.37); telokin; unnamed protein product
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
107589, 4638
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q15746, Q6PDN3
Gene Symbols:
MYLK
Immunogen:
Recombinant protein with Human MYLK aa 230-470
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: OOEP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ooep
Gene Alias: 2410146L05Rik; C6orf156; Factor located in oocytes permitting embryonic development; Floped; HOEP19; KH homology domain containing 2; KH homology domain-containing protein 2; KHDC2; Moep19; OEP19; oocyte and embryo protein 19; oocyte and embryo specific protein; oocyte- and embryo-specific protein 19; oocyte expressed protein; oocyte expressed protein homolog (dog); Oocyte-expressed protein homolog; OOEP; Sddr; STAT3 downstream gene and differentiation regulator
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 67968
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q9CWE6
Gene Symbols: Ooep
Immunogen: Synthetic peptide within mouse OOEP aa 51-100
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
OOEP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ooep
Gene Alias:
2410146L05Rik; C6orf156; Factor located in oocytes permitting embryonic development; Floped; HOEP19; KH homology domain containing 2; KH homology domain-containing protein 2; KHDC2; Moep19; OEP19; oocyte and embryo protein 19; oocyte and embryo specific protein; oocyte- and embryo-specific protein 19; oocyte expressed protein; oocyte expressed protein homolog (dog); Oocyte-expressed protein homolog; OOEP; Sddr; STAT3 downstream gene and differentiation regulator
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
67968
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q9CWE6
Gene Symbols:
Ooep
Immunogen:
Synthetic peptide within mouse OOEP aa 51-100
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: SIRT3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SIRT3
Gene Alias: 2310003L23Rik; AI848213; HGNC:14931; hSIRT3; mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase; mitochondrial protein lysine deacetylase; mSIR2L3; NAD-dependent deacetylase sirtuin-3; NAD-dependent deacetylase sirtuin-3, mitochondrial; NAD-dependent protein deacetylase sirtuin-3; NAD-dependent protein deacetylase sirtuin-3, mitochondrial; regulatory protein SIR2 homolog 3; silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3; silent mating type information regulation 2, S.cerevisiae, homolog 3; Sir2l3; sir2-like 3; SIR2-like protein 3; SIRT3; SIRT3L mitochondrial; sirtuin 3; sirtuin type 3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23410, 64384
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.: Q8R104, Q9NTG7
Gene Symbols: SIRT3
Immunogen: Synthetic peptide within residues of mouse SIRT3 aa 315-334
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SIRT3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SIRT3
Gene Alias:
2310003L23Rik; AI848213; HGNC:14931; hSIRT3; mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase; mitochondrial protein lysine deacetylase; mSIR2L3; NAD-dependent deacetylase sirtuin-3; NAD-dependent deacetylase sirtuin-3, mitochondrial; NAD-dependent protein deacetylase sirtuin-3; NAD-dependent protein deacetylase sirtuin-3, mitochondrial; regulatory protein SIR2 homolog 3; silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3; silent mating type information regulation 2, S.cerevisiae, homolog 3; Sir2l3; sir2-like 3; SIR2-like protein 3; SIRT3; SIRT3L mitochondrial; sirtuin 3; sirtuin type 3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23410, 64384
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.:
Q8R104, Q9NTG7
Gene Symbols:
SIRT3
Immunogen:
Synthetic peptide within residues of mouse SIRT3 aa 315-334
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG