PIPA586238
SHP-1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586238-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586238 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
SHP-1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTPN6
Gene Alias
70Z-SHP, EC 3.1.3.48, hcp, Hcph, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, HPTP1C, me, motheaten, protein tyrosine phosphatase, non-receptor type 6, protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, PTN6, Ptp1C, PTP-1C, Ptph6, PTPN6, PTPTY-42, SH2 phosphatase 1, SHP1, Shp-1, SHP-1L, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116689, 15170, 5777
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P29350, P29351, P81718
Gene Symbols
PTPN6
Immunogen
Synthetic peptide, corresponding to amino acids 500-550 of Human SHP-1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- SHP-1 (PTPN6) is a non-receptor protein tyrosine phosphatase that is expressed primarily in hematopoietic cells
- The enzyme is composed of two SH2 domains, a tyrosine phosphatase catalytic domain, and a carboxy-terminal regulatory domain
- SHP-1 removes phosphates from target proteins to downregulate several tyrosine kinase-regulated pathways
- In hematopoietic cells, the amino-terminal SH2 domain of SHP-1 binds to tyrosine phosphorylated erythropoietin receptors (EpoR) to negatively regulate hematopoietic growth
- Overexpression of SHP-1 in epithelial cells results in dephosphorylation of the Ros receptor tyrosine kinase and subsequent downregulation of Ros-dependent cell proliferation and transformation
- Following ligand binding in myeloid cells, SHP-1 associates with the IL-3R beta chain and downregulates IL-3-induced tyrosine phosphorylation and cell proliferation.
Compare Similar Items
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Antigen: SHP-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTPN6
Gene Alias: 70Z-SHP, EC 3.1.3.48, hcp, Hcph, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, HPTP1C, me, motheaten, protein tyrosine phosphatase, non-receptor type 6, protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, PTN6, Ptp1C, PTP-1C, Ptph6, PTPN6, PTPTY-42, SH2 phosphatase 1, SHP1, Shp-1, SHP-1L, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116689, 15170, 5777
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P29350, P29351, P81718
Gene Symbols: PTPN6
Immunogen: Synthetic peptide, corresponding to amino acids 500-550 of Human SHP-1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SHP-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTPN6
Gene Alias:
70Z-SHP, EC 3.1.3.48, hcp, Hcph, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, HPTP1C, me, motheaten, protein tyrosine phosphatase, non-receptor type 6, protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, PTN6, Ptp1C, PTP-1C, Ptph6, PTPN6, PTPTY-42, SH2 phosphatase 1, SHP1, Shp-1, SHP-1L, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116689, 15170, 5777
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P29350, P29351, P81718
Gene Symbols:
PTPN6
Immunogen:
Synthetic peptide, corresponding to amino acids 500-550 of Human SHP-1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: gamma Synuclein
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SNCG
Gene Alias: BCSG1, Breast cancer-specific gene 1 protein, C79089, Gamma-synuclein, persyn, PRSN, Sensory neuron synuclein, SNCG, SR, Synoretin, synuclein gamma, synuclein, gamma, synuclein, gamma (breast cancer-specific protein 1)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20618, 64347, 6623
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: O76070, Q63544, Q9Z0F7
Gene Symbols: SNCG
Immunogen: Synthetic peptide, corresponding to amino acids 81-130 of Human Synoretin.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
gamma Synuclein
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SNCG
Gene Alias:
BCSG1, Breast cancer-specific gene 1 protein, C79089, Gamma-synuclein, persyn, PRSN, Sensory neuron synuclein, SNCG, SR, Synoretin, synuclein gamma, synuclein, gamma, synuclein, gamma (breast cancer-specific protein 1)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20618, 64347, 6623
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
O76070, Q63544, Q9Z0F7
Gene Symbols:
SNCG
Immunogen:
Synthetic peptide, corresponding to amino acids 81-130 of Human Synoretin.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TrkA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ntrk1
Gene Alias: C80751, DKFZp781I14186, EC 2.7.10.1, gp140trk, high affinity nerve growth factor receptor, kinase TrkA, MTC, neurotrophic receptor tyrosine kinase 1, Neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase, receptor, type 1, Ntrk1, Oncogene TRK, p140-TrkA, Slow nerve growth factor receptor, Tkr, TRK, TRK1, TRK1-transforming tyrosine kinase protein, Trka, Trk-A, TrkA neurotrophin receptor, trkA proto-oncogene receptor, tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4914
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P04629
Gene Symbols: Ntrk1
Immunogen: Synthetic peptide, corresponding to amino acids 751-800 of Human Trk A.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TrkA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ntrk1
Gene Alias:
C80751, DKFZp781I14186, EC 2.7.10.1, gp140trk, high affinity nerve growth factor receptor, kinase TrkA, MTC, neurotrophic receptor tyrosine kinase 1, Neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase, receptor, type 1, Ntrk1, Oncogene TRK, p140-TrkA, Slow nerve growth factor receptor, Tkr, TRK, TRK1, TRK1-transforming tyrosine kinase protein, Trka, Trk-A, TrkA neurotrophin receptor, trkA proto-oncogene receptor, tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4914
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P04629
Gene Symbols:
Ntrk1
Immunogen:
Synthetic peptide, corresponding to amino acids 751-800 of Human Trk A.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TrkB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ntrk2
Gene Alias: AI848316, BDNF/NT-3 growth factors receptor, BDNF-tropomyosine receptor kinase B, C030027L06Rik, EC 2.7.10.1, GP145 TrkB, GP145TrkB, GP145-TrkB, GP145-TrkB/GP95-TrkB, GP95 TrkB, GP95-TrkB, hyperphagia, kinase TrkB, neural receptor protein-tyrosine kinase (trkB), neurotrophic receptor tyrosine kinase 2, neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, neurotrophic tyrosine receptor kinase type 2, NTRK 2, Ntrk2, OTTHUMP00000021573, OTTHUMP00000021574, OTTHUMP00000021576, OTTHUMP00000021577, RATTRKB1, Tkrb, Trk B, TRKB, trk-B, trkB protein, trkB tyrosine kinase, TRKB1, Tropomyosin-related kinase B, tyrosine kinase receptor B
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18212, 25054, 4915
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P15209, Q16620, Q63604
Gene Symbols: Ntrk2
Immunogen: Synthetic peptide corresponding to amino acids 480-530 of Human TrkB.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TrkB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ntrk2
Gene Alias:
AI848316, BDNF/NT-3 growth factors receptor, BDNF-tropomyosine receptor kinase B, C030027L06Rik, EC 2.7.10.1, GP145 TrkB, GP145TrkB, GP145-TrkB, GP145-TrkB/GP95-TrkB, GP95 TrkB, GP95-TrkB, hyperphagia, kinase TrkB, neural receptor protein-tyrosine kinase (trkB), neurotrophic receptor tyrosine kinase 2, neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, neurotrophic tyrosine receptor kinase type 2, NTRK 2, Ntrk2, OTTHUMP00000021573, OTTHUMP00000021574, OTTHUMP00000021576, OTTHUMP00000021577, RATTRKB1, Tkrb, Trk B, TRKB, trk-B, trkB protein, trkB tyrosine kinase, TRKB1, Tropomyosin-related kinase B, tyrosine kinase receptor B
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18212, 25054, 4915
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P15209, Q16620, Q63604
Gene Symbols:
Ntrk2
Immunogen:
Synthetic peptide corresponding to amino acids 480-530 of Human TrkB.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG