PIPA586039

B7-H4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586039-Each-of-1 In Stock ₹ 44,191.74

PIPA586039 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

B7-H4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Vtcn1

Gene Alias

B7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7s1; B7x; BC032925; EMBL:AAH95842.1}; FLJ22418; immune costimulatory protein B7-H4; PRO1291; Protein B7S1; RGD1311204; RP11-229A19.4; t cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; UNQ659/PRO1291; VCTN1; V-set domain containing T cell activation inhibitor 1; V-set domain containing T-cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; Vtcn1; vtcn1 {ECO:0000312

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

242122, 79679

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q7TSP5, Q7Z7D3

Gene Symbols

Vtcn1

Immunogen

Recombinant protein within Human B7-H4 aa 65-226

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Rabbit Polyclonal Antibody B7-H4 (B7x, VTCN1) a costimulatory protein which is reported to function as a negative regulator of T-cell mediated immunity
  • Although B7-H4 binds an unknown receptor, it is thought to deliver an inhibitory signal to T-cells preventing their proliferation, cell cycle progression and interleukin-2 production
  • B7-H4 deficient mice are only minimally affected; suggesting B7-H4 is important in the fine tuning of the T-cell mediated immune response
  • B7-H4 is expressed on activated T-cells, B-cells, monocytes and dendritic cells
  • Aberrant expression has been associated with cancers of the lung, breast and ovary in humans
  • B7-H4 is expressed primarily on the membrane of lymphoid cells, and as an immunoinhibitory protein that interacts with receptors on the surface of T lymphocytes, it is involved in mediating cellular and humoral immune responses
  • Overexpression of B7-H4 is associated with certain malignancies, including ovarian and breast cancer, which may be a mechanism by which tumor cells suppress T cell immunity and facilitate tumor progression
  • Further, VTCN1 may be a useful biomarker for the early detection of ovarian cancer and Renal Cell Carcinoma (RCC).

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA586039

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Antigen:
B7-H4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Vtcn1

Gene Alias:
B7 family member, H4; B7 homolog 4; B7 superfamily member 1; B7h.5; B7H4; B7-H4; B7s1; B7x; BC032925; EMBL:AAH95842.1}; FLJ22418; immune costimulatory protein B7-H4; PRO1291; Protein B7S1; RGD1311204; RP11-229A19.4; t cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; UNQ659/PRO1291; VCTN1; V-set domain containing T cell activation inhibitor 1; V-set domain containing T-cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; Vtcn1; vtcn1 {ECO:0000312

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
242122, 79679

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q7TSP5, Q7Z7D3

Gene Symbols:
Vtcn1

Immunogen:
Recombinant protein within Human B7-H4 aa 65-226

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA586041

--


Antigen:
AKR1C1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AKR1C1

Gene Alias:
17-beta-HSD 5; 17HSD type 5; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); 20-ALPHA-HSD; 20-alpha-hydroxysteroid dehydrogenase; 2-ALPHA-HSD; 3alpha-HSD; Akr1c1; Akr1c6; aldo-keto reductase C; aldo-keto reductase family 1 member C1; aldo-keto reductase family 1, member C1; aldo-keto reductase family 1, member C1 (aldehyde reductase); aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase); aldo-keto reductase family 1, member C6; C9; chlordecone reductase homolog HAKRC; DD1; DD1/DD2; DDH; DDH1; dihydrodiol dehydrogenase 1; dihydrodiol dehydrogenase 1/2; dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase; dihydrodiol dehydrogenase isoform DD1; estradiol 17 beta-dehydrogenase 5; estradiol 17-beta-dehydrogenase (A-specific); H-37; HAKRC; HBAB; hepatic dihydrodiol dehydrogenase; high-affinity

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1645, 83702

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P70694, Q04828

Gene Symbols:
AKR1C1, Akr1c6

Immunogen:
Recombinant protein within Human AKR1C1 aa 180-323

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA586043

--


Antigen:
Glypican 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GPC1

Gene Alias:
AI462976; glypican; glypican 1; glypican proteoglycan 1; glypican-1; Gpc1; GPI-anchored cell surface heparan sulfate proteoglycan; HSPG M12; HSPGM12; Secreted glypican-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2817

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P35052

Gene Symbols:
GPC1

Immunogen:
Synthetic peptide corresponding toHuman GPC1 aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA586048

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Antigen:
Cathepsin D

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ctsd

Gene Alias:
CatD; Cathepsin D; Cathepsin D heavy chain; Cathepsin D light chain; CathepsinD; CD; Ceroid lipofuscinosis neuronal 10; ceroid-lipofuscinosis, neuronal 10; CLN10; CPSD; CTSD; epididymis secretory sperm binding protein Li 130P; HEL-S-130P; lysosomal aspartyl peptidase; lysosomal aspartyl protease; MGC2311; OTTHUMP00000196039; OTTHUMP00000198692

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13033, 1509

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P07339, P18242

Gene Symbols:
Ctsd

Immunogen:
Synthetic peptide within Human Cathepsin D aa 373-412

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG