PIPA586075
STAT3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586075-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586075 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
STAT3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STAT3
Gene Alias
1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20848, 25125, 6774
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P40763, P42227, P52631
Gene Symbols
STAT3
Immunogen
Synthetic peptide, corresponding to amino acids 700-750 of Human Stat3.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
- Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
- STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
- Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
- In humans, the STAT3 gene is located on the q arm of chromosome 17
- STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
- The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
- STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
- The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
- Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
- Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.
Compare Similar Items
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Antigen: STAT3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT3
Gene Alias: 1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20848, 25125, 6774
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P40763, P42227, P52631
Gene Symbols: STAT3
Immunogen: Synthetic peptide, corresponding to amino acids 700-750 of Human Stat3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
STAT3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT3
Gene Alias:
1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20848, 25125, 6774
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P40763, P42227, P52631
Gene Symbols:
STAT3
Immunogen:
Synthetic peptide, corresponding to amino acids 700-750 of Human Stat3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Syk
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Syk
Gene Alias: DKFZp313N1010, EC 2.7.10.2, FLJ25043, FLJ37489, HGNC:11205, kinase Syk, KSYK, p72Syk, p72-Syk, ptk72, SP1, spleen associated tyrosine kinase, spleen tyrosine kinase, SYK, syk signaling, Sykb, tyrosine-kinase syk, tyrosine-protein kinase SYK
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20963, 25155, 6850
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P43405, P48025, Q64725
Gene Symbols: Syk
Immunogen: Synthetic peptide, corresponding to amino acids 300-350 of Human Syk.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Syk
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Syk
Gene Alias:
DKFZp313N1010, EC 2.7.10.2, FLJ25043, FLJ37489, HGNC:11205, kinase Syk, KSYK, p72Syk, p72-Syk, ptk72, SP1, spleen associated tyrosine kinase, spleen tyrosine kinase, SYK, syk signaling, Sykb, tyrosine-kinase syk, tyrosine-protein kinase SYK
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20963, 25155, 6850
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P43405, P48025, Q64725
Gene Symbols:
Syk
Immunogen:
Synthetic peptide, corresponding to amino acids 300-350 of Human Syk.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: c-Abl
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ABL1
Gene Alias: Abelson murine leukemia oncogene, Abelson murine leukemia viral (v-abl) oncogene homolog 1, abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Abl, Abl 1 antib, ABL proto-oncogene 1, non-receptor tyrosine kinase, Abl1, ABL2, ABLL, AI325092, ARG, B30, bcr/abl, bcr/c-abl oncogene protein, c-ABL, c-abl oncogene 1, non-receptor tyrosine kinase, c-abl oncogene 1, receptor tyrosine kinase, c-ABL1, E430008G22Rik, JTK7, p150, Proto-oncogene c-Abl, proto-oncogene tyrosine-protein kinase ABL1, RP11-83J21.1, Tyrosine kinase ARG, tyrosine-protein kinase ABL1, v-abl, v-abl Abelson murine leukemia oncogene 1, v-abl Abelson murine leukemia viral oncogene 1, v-abl Abelson murine leukemia viral oncogene homolog 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11350, 25, 311860
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P00519, P00520
Gene Symbols: ABL1
Immunogen: Synthetic peptide, corresponding to amino acids 171-120 of Human ABL1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
c-Abl
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABL1
Gene Alias:
Abelson murine leukemia oncogene, Abelson murine leukemia viral (v-abl) oncogene homolog 1, abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Abl, Abl 1 antib, ABL proto-oncogene 1, non-receptor tyrosine kinase, Abl1, ABL2, ABLL, AI325092, ARG, B30, bcr/abl, bcr/c-abl oncogene protein, c-ABL, c-abl oncogene 1, non-receptor tyrosine kinase, c-abl oncogene 1, receptor tyrosine kinase, c-ABL1, E430008G22Rik, JTK7, p150, Proto-oncogene c-Abl, proto-oncogene tyrosine-protein kinase ABL1, RP11-83J21.1, Tyrosine kinase ARG, tyrosine-protein kinase ABL1, v-abl, v-abl Abelson murine leukemia oncogene 1, v-abl Abelson murine leukemia viral oncogene 1, v-abl Abelson murine leukemia viral oncogene homolog 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11350, 25, 311860
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P00519, P00520
Gene Symbols:
ABL1
Immunogen:
Synthetic peptide, corresponding to amino acids 171-120 of Human ABL1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Fyn
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Fyn
Gene Alias: AI448320, AW552119, C syn protooncogene, c-syn protooncogene, EC 2.7.10.2, Fyn, fyn {ECO:0000312, FYN oncogene related to SRC, FGR, YES, Fyn proto-oncogene, FYN proto-oncogene, Src family tyrosine kinase, kinase Fyn, MGC45350, OKT3-induced calcium influx regulator, OTTHUMP00000017916, OTTHUMP00000017917, P59 p59-Fyn, p59-Fyn, Proto-oncogene c-Fyn, Protooncogene Syn, proto-oncogene Syn, proto-oncogene tyrosine-protein kinase Fyn, RGD:2641}, RP1-66H14.1, SLK, Src Kinase p59, Src like kinase, src/yes-related novel, src-like kinase, SYN, tyrosine kinase p59fyn(T), tyrosine-protein kinase Fyn
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14360, 25150, 2534
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P06241, P39688, Q62844
Gene Symbols: Fyn
Immunogen: Synthetic peptide, corresponding to amino acids 501-550 of Human Fyn.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Fyn
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Fyn
Gene Alias:
AI448320, AW552119, C syn protooncogene, c-syn protooncogene, EC 2.7.10.2, Fyn, fyn {ECO:0000312, FYN oncogene related to SRC, FGR, YES, Fyn proto-oncogene, FYN proto-oncogene, Src family tyrosine kinase, kinase Fyn, MGC45350, OKT3-induced calcium influx regulator, OTTHUMP00000017916, OTTHUMP00000017917, P59 p59-Fyn, p59-Fyn, Proto-oncogene c-Fyn, Protooncogene Syn, proto-oncogene Syn, proto-oncogene tyrosine-protein kinase Fyn, RGD:2641}, RP1-66H14.1, SLK, Src Kinase p59, Src like kinase, src/yes-related novel, src-like kinase, SYN, tyrosine kinase p59fyn(T), tyrosine-protein kinase Fyn
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14360, 25150, 2534
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P06241, P39688, Q62844
Gene Symbols:
Fyn
Immunogen:
Synthetic peptide, corresponding to amino acids 501-550 of Human Fyn.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG