PIPA586077

c-Abl Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586077-Each-of-1 In Stock ₹ 44,277.30

PIPA586077 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

c-Abl

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ABL1

Gene Alias

Abelson murine leukemia oncogene, Abelson murine leukemia viral (v-abl) oncogene homolog 1, abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Abl, Abl 1 antib, ABL proto-oncogene 1, non-receptor tyrosine kinase, Abl1, ABL2, ABLL, AI325092, ARG, B30, bcr/abl, bcr/c-abl oncogene protein, c-ABL, c-abl oncogene 1, non-receptor tyrosine kinase, c-abl oncogene 1, receptor tyrosine kinase, c-ABL1, E430008G22Rik, JTK7, p150, Proto-oncogene c-Abl, proto-oncogene tyrosine-protein kinase ABL1, RP11-83J21.1, Tyrosine kinase ARG, tyrosine-protein kinase ABL1, v-abl, v-abl Abelson murine leukemia oncogene 1, v-abl Abelson murine leukemia viral oncogene 1, v-abl Abelson murine leukemia viral oncogene homolog 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11350, 25, 311860

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

P00519, P00520

Gene Symbols

ABL1

Immunogen

Synthetic peptide, corresponding to amino acids 171-120 of Human ABL1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response
  • Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns c-Abl into an oncogene
  • The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for c-Abl
  • In chronic myelogenous leukemia and a subset of acute lymphoblastic leukemias, the c-Abl proto oncogene undergoes a (9;22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome)
  • As the result of the fusion of c-Abl sequences from chromosome 9 to the Bcr gene on chromosome 22
  • The c-Abl oncogene was initially identified as the viral transforming gene of Abelson murine leukemia virus (A-MuLV)
  • c-ABL potentially regulates DNA repair by activating the proapoptotic pathway when the DNA damage is too severe to be repaired.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA586077

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Antigen:
c-Abl

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABL1

Gene Alias:
Abelson murine leukemia oncogene, Abelson murine leukemia viral (v-abl) oncogene homolog 1, abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Abl, Abl 1 antib, ABL proto-oncogene 1, non-receptor tyrosine kinase, Abl1, ABL2, ABLL, AI325092, ARG, B30, bcr/abl, bcr/c-abl oncogene protein, c-ABL, c-abl oncogene 1, non-receptor tyrosine kinase, c-abl oncogene 1, receptor tyrosine kinase, c-ABL1, E430008G22Rik, JTK7, p150, Proto-oncogene c-Abl, proto-oncogene tyrosine-protein kinase ABL1, RP11-83J21.1, Tyrosine kinase ARG, tyrosine-protein kinase ABL1, v-abl, v-abl Abelson murine leukemia oncogene 1, v-abl Abelson murine leukemia viral oncogene 1, v-abl Abelson murine leukemia viral oncogene homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11350, 25, 311860

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P00519, P00520

Gene Symbols:
ABL1

Immunogen:
Synthetic peptide, corresponding to amino acids 171-120 of Human ABL1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586079

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Antigen:
Fyn

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fyn

Gene Alias:
AI448320, AW552119, C syn protooncogene, c-syn protooncogene, EC 2.7.10.2, Fyn, fyn {ECO:0000312, FYN oncogene related to SRC, FGR, YES, Fyn proto-oncogene, FYN proto-oncogene, Src family tyrosine kinase, kinase Fyn, MGC45350, OKT3-induced calcium influx regulator, OTTHUMP00000017916, OTTHUMP00000017917, P59 p59-Fyn, p59-Fyn, Proto-oncogene c-Fyn, Protooncogene Syn, proto-oncogene Syn, proto-oncogene tyrosine-protein kinase Fyn, RGD:2641}, RP1-66H14.1, SLK, Src Kinase p59, Src like kinase, src/yes-related novel, src-like kinase, SYN, tyrosine kinase p59fyn(T), tyrosine-protein kinase Fyn

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14360, 25150, 2534

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P06241, P39688, Q62844

Gene Symbols:
Fyn

Immunogen:
Synthetic peptide, corresponding to amino acids 501-550 of Human Fyn.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586080

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Antigen:
ETS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ETS1

Gene Alias:
AI196000, AI448617, Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1, avian erythroblastosis virus E26 oncogene 1, c-ets protein, c-ets1, c-ets-1, c-ets-1 oncogene, c-ets-1 protein, c-ets-alpha, c-ets-beta, D230050P06, E26 avian leukemia oncogene 1, 5' domain, Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1), ets protein, ETS proto-oncogene 1, transcription factor, Ets1, ETS-1, ETS-1A, ETS-1B, Ets-1Delta(III-VI), Etsoncb, EWSR2, FLJ10768, oncoprotein, p54, p54 transcription factor, protein C-ets-1, TNFAIP3 interacting protein 1, TNIP1, Tpl1, transforming protein p54/c-ets-1, transforming protein p68/c-ets-1, tumor progression locus 1, unnamed protein product, v-ets avian erythroblastosis virus E2 oncogene homolog 1, v-ets avian erythroblastosis virus E26 oncogene homolog 1, v-ets erythroblastosis virus E26 oncogene homolog 1, virion-associated nuclear-shuttling protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2113, 23871, 24356

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P14921, P27577, P41156

Gene Symbols:
ETS1

Immunogen:
Synthetic peptide, corresponding to the N-terminus of Human ETS1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586081

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Antigen:
PKC alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKCA

Gene Alias:
AAG6, aging-associated gene 6, AI875142, EC 2.7.11.13, FHC, FTH, FTHL6, im:7139045, kinase PKC-alpha, KPCA, MGC104426, PIG15, PKC III, Pkca, PKC-A, PKC-alpha, PKC-III, PKRCA, PLIF, PRKACA, Prkca, prkcaa, protein kinase C, protein kinase C alpha, protein kinase C alpha type, protein kinase C alpha type, protein kinase C, alpha, a, protein kinase C, alpha, protein kinase C, alpha, a, protein kinase c-alpha, si:dkey-8l19.1, Unknown (protein for IMAGE:7139045), unnamed protein product

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18750, 24680, 5578

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P05696, P17252, P20444

Gene Symbols:
PRKCA

Immunogen:
Synthetic peptide, corresponding to amino acids 600-650 of Human PKC alpha.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG