PIPA587378

c-Raf Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587378-Each-of-1 In Stock ₹ 44,191.74

PIPA587378 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

c-Raf

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Raf1

Gene Alias

6430402F14Rik, AA990557, BB129353, CMD1NN, CRAF, C-RAF, C-Raf proto-oncogene, serine/threonine kinase, Craf1, Craf1 transforming, D830050J10Rik, EC 2.7.11.1, kinase Raf1, murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV), murine sarcoma 3611 oncogene 1, NS5, Oncogene RAF1, OTTHUMP00000207813, OTTHUMP00000209389, proto-oncogene c-RAF, RAF, raf proto-oncogene serine/threonine protein kinase, RAF proto-oncogene serine/threonine-protein kinase, RAF1, Raf-1, Raf-1 proto-oncogene, serine/threonine kinase, sarcoma 3611 oncogene, v-Raf, v-raf-1 leukemia viral oncogene 1, vraf1 murine le, v-raf-1 murine leukemia viral oncogene homolog 1, v-raf-1 murine leukemia viral oncogene-like protein 1, v-raf-leukemia viral oncogene 1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

110157, 5894

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.99 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P04049, Q99N57

Gene Symbols

Raf1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 190-350 of human Raf1 (NP_0028711)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: IRQLLLFPNS TIGDSGVPAL PSLTMRRMRE SVSRMPVSSQ HRYSTPHAFT FNTSSPSSEG SLSQRQRSTS TPNVHMVSTT LPVDSRMIED AIRSHSESAS PSALSSSPNN LSPTGWSQPK TPVPAQRERA PVSGTQEKNK IRPRGQRDSS YYWEIEASEV M; Positive Samples: 293T, Jurkat, HeLa, MCF7, HepG2, NIH/3T3, Mouse liver, Rat skeletal muscle; Cellular Location: Cell membrane, Cytoplasm, Mitochondrion, Nucleus Raf-1 (c-Raf) is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly
  • Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2
  • Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration
  • Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA587378

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Antigen:
c-Raf

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Raf1

Gene Alias:
6430402F14Rik, AA990557, BB129353, CMD1NN, CRAF, C-RAF, C-Raf proto-oncogene, serine/threonine kinase, Craf1, Craf1 transforming, D830050J10Rik, EC 2.7.11.1, kinase Raf1, murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV), murine sarcoma 3611 oncogene 1, NS5, Oncogene RAF1, OTTHUMP00000207813, OTTHUMP00000209389, proto-oncogene c-RAF, RAF, raf proto-oncogene serine/threonine protein kinase, RAF proto-oncogene serine/threonine-protein kinase, RAF1, Raf-1, Raf-1 proto-oncogene, serine/threonine kinase, sarcoma 3611 oncogene, v-Raf, v-raf-1 leukemia viral oncogene 1, vraf1 murine le, v-raf-1 murine leukemia viral oncogene homolog 1, v-raf-1 murine leukemia viral oncogene-like protein 1, v-raf-leukemia viral oncogene 1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110157, 5894

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.99 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P04049, Q99N57

Gene Symbols:
Raf1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 190-350 of human Raf1 (NP_0028711)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587381

--


Antigen:
DOK4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DOK4

Gene Alias:
docking protein 4, Dok4, Downstream of tyrosine kinase 4, insulin receptor substrate 5, IRS5, IRS-5

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114255, 361364, 55715

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.09 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q8TEW6, Q99KE3

Gene Symbols:
DOK4

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human DOK4 (NP_0605802)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587382

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Antigen:
ERK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPK1

Gene Alias:
9030612K14Rik, AA407128, AU018647, C78273, ERK, ERK2, ERK-2, ERT1, extracellular signal-regulated kinase 2, extracellular signal-regulated kinase-2, extracellular-signal-regulated kinase 2, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, Mapk, MAPK 1, MAPK 2, Mapk1, MAPK2, mitogen activated protein kinase 1, mitogen-activated protein kinase 1, Mitogen-activated protein kinase 2, p38, p40, p41, p41mapk, P42MAPK, p42-MAPK, Prkm1, PRKM2, protein tyrosine kinase ERK2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116590, 26413, 5594

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
2.29 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P28482, P63085, P63086

Gene Symbols:
MAPK1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ERK2 (NP_0027363)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587383

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Antigen:
SIRT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SIRT1

Gene Alias:
75SirT1, AA673258, hSIR2, hSIRT1, mSIR2a, NAD-dependent deacetylase sirtuin-1, NAD-dependent protein deacetylase sirtuin-1, OTTHUMP00000198111, OTTHUMP00000198112, Regulatory protein SIR2 homolog 1, RP11-57G10.3, SIR2, Sir2a, SIR2alpha, SIR2L1, sir2-like 1, SIR2-like protein 1, SIRT 1, SIRT1, SIRT-1, SirtT1 75 kDa fragment, sirtuin 1, sirtuin 1 ((silent mating type information regulation 2, homolog) 1, sirtuin type 1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23411, 93759

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot, Western Blot

Concentration:
2.68 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
Q923E4, Q96EB6

Gene Symbols:
SIRT1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 201-300 of human SIRT1 (NP_0363702)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG