PIPA586128

TPL2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586128-Each-of-1 In Stock ₹ 44,705.10

PIPA586128 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TPL2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP3K8

Gene Alias

augmented in rheumatoid arthritis 2, AURA2, Cancer Osaka thyroid oncogene, cancer Osaka thyroid, oncogene, CCOT, c-COT, COT, cot (cancer Osaka thyroid) oncogene, COT proto-oncogene serine/threonine-protein kinase, Cot/Tpl2, D17TPL2, EC 1.14.16.2, Est, Estf, Ewing sarcoma transformant, FLJ10486, M3K8, MAP3K 8, Map3k8, MEKK8, mitogen activated protein kinase kinase kinase 8, mitogen-activated protein kinase kinase kinase 8, Protein kinase cot, Proto-oncogene c-Cot, proto-oncogene serine/threoine protein kinase, serine/threonine kinase (Tpl-2), serine/threonine-protein kinase cot, TH isoform 3, TH isoform a, TH-4, TPL 2, Tpl2, TPL-2, Tumor progression locus 2, TY3H, TYH

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

116596, 1326, 26410

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

P41279, Q07174, Q63562

Gene Symbols

MAP3K8

Immunogen

Synthetic peptide, corresponding to amino acids 250-300 of Human Cot.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • MAP3K8 (COT) is a serine/threonine kinase which can activate both the MAP and JNK kinase pathways and plays a role in the cell cycle
  • Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase (MAPKKK or MEKK)
  • MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK
  • The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells
  • MEKK8 is able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105
  • This cytoplasmic protein is expressed in several normal tissues and human tumor-derived cell lines
  • The 58 kDa form is activated specifically during the S and G2/M phases of the cell cycle
  • The longer form undergoes phosphorylation on Ser residues mainly, and the shorter form on both Ser and Thr residues.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA586128

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Antigen:
TPL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K8

Gene Alias:
augmented in rheumatoid arthritis 2, AURA2, Cancer Osaka thyroid oncogene, cancer Osaka thyroid, oncogene, CCOT, c-COT, COT, cot (cancer Osaka thyroid) oncogene, COT proto-oncogene serine/threonine-protein kinase, Cot/Tpl2, D17TPL2, EC 1.14.16.2, Est, Estf, Ewing sarcoma transformant, FLJ10486, M3K8, MAP3K 8, Map3k8, MEKK8, mitogen activated protein kinase kinase kinase 8, mitogen-activated protein kinase kinase kinase 8, Protein kinase cot, Proto-oncogene c-Cot, proto-oncogene serine/threoine protein kinase, serine/threonine kinase (Tpl-2), serine/threonine-protein kinase cot, TH isoform 3, TH isoform a, TH-4, TPL 2, Tpl2, TPL-2, Tumor progression locus 2, TY3H, TYH

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116596, 1326, 26410

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P41279, Q07174, Q63562

Gene Symbols:
MAP3K8

Immunogen:
Synthetic peptide, corresponding to amino acids 250-300 of Human Cot.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586130

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Antigen:
CAS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CSE1L

Gene Alias:
2610100P18Rik, AA407533, Capts, CAS, Cellular apoptosis susceptibility protein, chromosome segregation 1 like, chromosome segregation 1-like (S. cerevisiae), chromosome segregation 1-like protein, CSE1, CSE1 chromosome segregation 1 like, CSE1 chromosome segregation 1-like, CSE1 chromosome segregation 1-like (yeast), CSE1L, Exp2, exportin-2, Importin-alpha re-exporter, MGC117283, MGC130036, MGC130037, XPO2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110750, 1434, 362273

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P55060, Q9ERK4

Gene Symbols:
CSE1L

Immunogen:
Synthetic peptide, corresponding to amino acids N-terminus of Human CSE1L.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586131

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Antigen:
Cytochrome C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cycs

Gene Alias:
CG17903, CG17903-PA, CG17903-PB, CRF, CYC, CYC2, Cycs, CYCSA, Cyct-c-p, Cyt c, cyt c-p, cyt.c, CytC, Cyt-c, CYTC2, Cyt-c2, CytC-2, cyt-c-p, cytC-p, Cyt-c-p-PA, Cyt-c-p-PB, Cytochrome c, cytochrome c DC4, Cytochrome c proximal, Cytochrome C, expressed in somatic tissues, cytochrome c, somatic, Cytochrome c-2, cytochrome c-like, cytochrome c-like protein, Cytochrome c-proximal, cytochrome-c-p, Cytochrome-c-proximal, DC4, dCyt.C-p, DMc01, Dmel\CG17903, Dmel_CG17903, hc1, HCS, l(2)k13905, lethal (2) k13905, LOC100341175, LOC100357840, MGC128356 protein, pDMc01, RH17228p, THC4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13063, 25309, 54205

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P62897, P62898, P99999

Gene Symbols:
Cycs

Immunogen:
Synthetic peptide, corresponding to the N-terminal of Human Cytochrome c.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA586135

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Antigen:
DP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TFDP1

Gene Alias:
AS1, ASRT1, cell cycle regulatory transcription factor DP1, DILC, down-regulated in liver cancer stem cells, DP, DP1, Dp-1, DRTF1, DRTF1-polypeptide 1, E2F dimerization partner 1, E2F-related transcription factor, MGC49004, OTTHUMP00000018767, Tfdp1, transcription factor Dp 1, transcription factor Dp-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100360176, 21781, 361178, 7027

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q08639, Q14186

Gene Symbols:
LOC100360176, TFDP1

Immunogen:
Synthetic peptide, corresponding to amino acids 360-418 of Human TFDP1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG