PIPA587047
MST1 (STK4) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587047-Each-of-1 | In Stock | ₹ 50,565.96 |
PIPA587047 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,565.96
GST (18%): ₹ 9,101.873
Total Price: ₹ 59,667.833
Antigen
MST1 (STK4)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Stk4
Gene Alias
AI447339, AU020804, EC 2.7.11.1, Kas-2, kinase MST1, kinase responsive to stress 2, KRS2, Mammalian STE20-like protein kinase 1, mammalian sterile 20-like 1, MST1, MST-1, MST1/C, MST1/N, serine/threonine kinase 4, serine/threonine-protein kinase 4, Serine/threonine-protein kinase 4 18kDa subunit, Serine/threonine-protein kinase 4 37kDa subunit, Serine/threonine-protein kinase Krs-2, STE20-like kinase MST1, sterile 20-like kinase 1, STK4, TIIAC, Yeast Sps1/Ste20-related kinase 3, Ysk3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
311622, 58231, 6789
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
Q13043, Q9JI11
Gene Symbols
Stk4
Immunogen
Recombinant protein of human STK4.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- STK4 (MST1) is a serine/threonine kinase which may be involved in apoptosis
- It is possible that this protein induces the chromatin condensation observed in this process
- STK4 is a stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation
- It is a key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
- The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
- Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration
- STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation.
Compare Similar Items
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Antigen: MST1 (STK4)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Stk4
Gene Alias: AI447339, AU020804, EC 2.7.11.1, Kas-2, kinase MST1, kinase responsive to stress 2, KRS2, Mammalian STE20-like protein kinase 1, mammalian sterile 20-like 1, MST1, MST-1, MST1/C, MST1/N, serine/threonine kinase 4, serine/threonine-protein kinase 4, Serine/threonine-protein kinase 4 18kDa subunit, Serine/threonine-protein kinase 4 37kDa subunit, Serine/threonine-protein kinase Krs-2, STE20-like kinase MST1, sterile 20-like kinase 1, STK4, TIIAC, Yeast Sps1/Ste20-related kinase 3, Ysk3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 311622, 58231, 6789
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q13043, Q9JI11
Gene Symbols: Stk4
Immunogen: Recombinant protein of human STK4.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MST1 (STK4)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Stk4
Gene Alias:
AI447339, AU020804, EC 2.7.11.1, Kas-2, kinase MST1, kinase responsive to stress 2, KRS2, Mammalian STE20-like protein kinase 1, mammalian sterile 20-like 1, MST1, MST-1, MST1/C, MST1/N, serine/threonine kinase 4, serine/threonine-protein kinase 4, Serine/threonine-protein kinase 4 18kDa subunit, Serine/threonine-protein kinase 4 37kDa subunit, Serine/threonine-protein kinase Krs-2, STE20-like kinase MST1, sterile 20-like kinase 1, STK4, TIIAC, Yeast Sps1/Ste20-related kinase 3, Ysk3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
311622, 58231, 6789
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q13043, Q9JI11
Gene Symbols:
Stk4
Immunogen:
Recombinant protein of human STK4.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: HMGCL
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HMGCL
Gene Alias: 3-hydroxy-3-methylglutarate-CoA lyase, 3-hydroxy-3-methylglutaryl-CoA lyase, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase, 3-hydroxymethyl-3-methylglutaryl-CoA lyase, 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase, AW476067, HL, Hmgcl, HMG-CoA lyase, hydroxymethylglutaricaciduria, hydroxymethylglutaryl-CoA lyase, mitochondrial, mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15356, 3155, 79238
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P35914, P38060, P97519
Gene Symbols: HMGCL
Immunogen: Recombinant protein of human HMGCL.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HMGCL
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HMGCL
Gene Alias:
3-hydroxy-3-methylglutarate-CoA lyase, 3-hydroxy-3-methylglutaryl-CoA lyase, 3-hydroxy-3-methylglutaryl-Coenzyme A lyase, 3-hydroxymethyl-3-methylglutaryl-CoA lyase, 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase, AW476067, HL, Hmgcl, HMG-CoA lyase, hydroxymethylglutaricaciduria, hydroxymethylglutaryl-CoA lyase, mitochondrial, mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15356, 3155, 79238
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P35914, P38060, P97519
Gene Symbols:
HMGCL
Immunogen:
Recombinant protein of human HMGCL.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Cytochrome P450 Reductase
Classification: Polyclonal
Conjugate: Unconjugated
Gene: POR
Gene Alias: 4933424M13Rik, CCR, CPR, CY DKFZp686G04235, CYPOR, cytochrome p450 oxidoreductase, cytochrome P450 reductase, DKFZp686G04235, FLJ26468, I79_007261, LOC101115252, NADPH Cytochrome, NADPH-cytochrome P450 oxidoreductase, NADPH-cytochrome P-450 oxidoreductase, NADPH-cytochrome P450 reductase, NADPH--cytochrome P450 reductase, NADPH-cytochrome P-450 reductase, NADPH-dependent cytochrome P450 reductase, P450 (cytochrome) oxidoreductase, P450 Reductase, P450R, Por, unnamed protein product
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18984, 29441, 5447
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P00388, P16435, P37040
Gene Symbols: POR
Immunogen: Recombinant protein of human POR.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Cytochrome P450 Reductase
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
POR
Gene Alias:
4933424M13Rik, CCR, CPR, CY DKFZp686G04235, CYPOR, cytochrome p450 oxidoreductase, cytochrome P450 reductase, DKFZp686G04235, FLJ26468, I79_007261, LOC101115252, NADPH Cytochrome, NADPH-cytochrome P450 oxidoreductase, NADPH-cytochrome P-450 oxidoreductase, NADPH-cytochrome P450 reductase, NADPH--cytochrome P450 reductase, NADPH-cytochrome P-450 reductase, NADPH-dependent cytochrome P450 reductase, P450 (cytochrome) oxidoreductase, P450 Reductase, P450R, Por, unnamed protein product
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18984, 29441, 5447
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P00388, P16435, P37040
Gene Symbols:
POR
Immunogen:
Recombinant protein of human POR.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: UCHL3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: UCHL3
Gene Alias: RGD1561196, testicular tissue protein Li 221, ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L3, ubiquitin C-terminal hydrolase L3, Ubiquitin thioesterase L3, ubiquitin thiolesterase, UCHL3, UCH-L3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 498560, 50933, 7347
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P15374, Q91Y78, Q9JKB1
Gene Symbols: UCHL3
Immunogen: Recombinant protein of human UCHL3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
UCHL3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
UCHL3
Gene Alias:
RGD1561196, testicular tissue protein Li 221, ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L3, ubiquitin C-terminal hydrolase L3, Ubiquitin thioesterase L3, ubiquitin thiolesterase, UCHL3, UCH-L3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
498560, 50933, 7347
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P15374, Q91Y78, Q9JKB1
Gene Symbols:
UCHL3
Immunogen:
Recombinant protein of human UCHL3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG